Layered collagen materials and methods of making the same
The present disclosure provides layered collagen materials comprising one or more collagen/polymer matrix layers. The collagen/polymer matrix layer(s) are formed of a collagen blended with one or more polymers. The collagen blended within the polymer(s) can be dissolved within the polymer(s). The one or more collagen/polymer matrix layers can be attached to a substrate layer, for example a fabric layer.
1. A layered collagen material, comprising:
a substrate layer; and
a collagen/polymer matrix layer attached to a surface of the substrate layer, the collagen/polymer matrix layer comprising collagen dissolved within a polymeric matrix material.
2. The layered collagen material of claim 1 , wherein the collagen/polymer matrix layer is transparent.
3. The layered collagen material of claim 1 , wherein the collagen is natural collagen, recombinant collagen, or a combination thereof.
4. The layered collagen material of claim 1 , further comprising a second collagen/polymer matrix layer disposed between the collagen/polymer matrix layer and the substrate layer.
5. The layered collagen material of claim 4 , wherein the collagen/polymer matrix layer has a first density and the second collagen/polymer matrix layer has a second density, and wherein the first density is greater than the second density.
6. The layered collagen material of claim 4 , wherein the collagen/polymer matrix layer has a first dry weight and the second collagen/polymer matrix layer has a second dry weight, and wherein the first dry weight is less than the second dry weight.
7. The layered collagen material of claim 4 , wherein the second collagen/polymer matrix layer comprises a foam stabilizer.
8. The layered collagen material of claim 4 , further comprising a third collagen/polymer matrix layer disposed between the second collagen/polymer matrix layer and the substrate layer.
9. The layered collagen material of claim 8 , wherein the collagen/polymer matrix layer has a first density, the second collagen/polymer matrix layer has a second density, and the third collagen/polymer matrix layer has a third density, and wherein the first density is greater than the second density and the third density.
10. The layered collagen material of claim 8 , wherein the collagen/polymer matrix layer has a first dry weight, the second collagen/polymer matrix layer has a second dry weight, and the third collagen/polymer matrix layer has a third dry weight, and wherein the first dry weight is less than the second dry weight and the third dry weight.
11. The layered collagen material of claim 8 , wherein the third collagen/polymer matrix layer comprises a foam stabilizer.
12. The layered collagen material of claim 1 , wherein the polymeric matrix material comprises a polyurethane, a polyacrylate, an acrylic acid copolymer, a polyacrylamide, a polyethylene oxide, a polyvinyl alcohol, or a combination thereof.
13. The layered collagen material of claim 1 , wherein the polymeric matrix material comprises a polyurethane.
14. The layered collagen material of claim 13 , wherein the polyurethane is bio-polyurethane.
15. The layered collagen material of claim 13 , wherein the polyurethane is a water-soluble polyurethane.
16. The layered collagen material of claim 1 , wherein the collagen/polymer matrix layer comprises a fatliquor.
17. The layered collagen material of claim 1 , wherein the collagen/polymer matrix layer comprises a coloring agent.
18. The layered collagen material of claim 17 , wherein the coloring agent is a dye.
19. The layered collagen material of claim 1 , wherein the collagen/polymer matrix layer is tanned.
20. The layered collagen material of claim 1 , wherein the substrate layer comprises a textile layer.
21. The layered collagen material of claim 20 , wherein the textile layer comprises at least one of: a woven textile layer, non-woven textile layer, or a knit textile layer.
22. The layered collagen material of claim 1 , further comprising a basecoat layer disposed over a surface of the collagen/polymer matrix layer opposite the substrate layer.
23. The layered collagen material of claim 22 , further comprising a top-coat layer disposed over a surface of the basecoat layer opposite the collagen/polymer matrix layer.
24. The layered collagen material of claim 1 , wherein the collagen is at least about 60% identical to SEQ ID NO: 1.
25. A method of making a layered collagen material, the method comprising:
blending a polymer dispersed in a solvent with collagen to form a blended mixture in the solvent;
disposing a layer of the blended mixture in the solvent over a surface of a sacrificial layer;
removing the solvent from the blended mixture to form a collagen/polymer matrix layer, the collagen/polymer matrix layer comprising the collagen dissolved within the polymer; and
attaching the collagen/polymer matrix layer to a substrate layer.
26. A method of making a layered collagen material, the method comprising:
blending a polymer dispersed in a solvent with collagen to form a blended mixture in the solvent;
disposing a layer of the blended mixture in the solvent over a substrate layer; and
removing the solvent from the blended mixture to form a collagen/polymer matrix layer, the collagen/polymer matrix layer comprising the collagen dissolved within the polymer.