Composition for preventing hair loss or promoting hair development, comprising irone as active ingredient
View Patent ↗Provided is a composition for preventing hair loss or promoting hair development, comprising, as an active ingredient, irone or a pharmaceutically acceptable salt thereof. More specifically, provided is a pharmaceutical composition, a quasi-drug composition, a cosmetic composition, or a health functional food composition, for preventing hair loss, treating hair loss, promoting hair development, or promoting hair growth, the composition comprising irone or a salt thereof as an active ingredient. The composition not only contains, as an active ingredient, a natural compound having no adverse effects even when administered for a long period of time with respect to hair loss, a chronic disease, but also exhibits excellent and stable efficacy in hair development and hair growth, which allows the composition to be usefully used as an agent for preventing or treating hair loss, or a pharmaceutical, quasi-drug, cosmetic, or health functional food composition for promoting hair development or hair growth.
1. A method for treating hair loss, or promoting hair development or hair growth, the method comprising administering a composition including irone or a pharmaceutically acceptable salt thereof as an active ingredient to a subject in need thereof.
2. The method according to claim 1 , wherein the composition increases expression of at least one selected from the group consisting of β-catenin, protein kinase A Cα (PKA Cα), lymphoid enhancer factor-1 (LEF-1), insulin-like growth factor-1 (IGF-1), vascular endothelial growth factor (VEGF), and cyclin D.
3. The method according to claim 1 ,
wherein the composition is a pharmaceutical composition, a quasi-drug composition, a cosmetic composition or a health functional food composition.
4. The method according to claim 3 ,
wherein the pharmaceutical composition is a formulation for skin external use which is selected from the group consisting of a cream, a gel, a patch, a spray, an ointment, a plaster, a lotion, a liniment, a paste, and a cataplasm.
5. The method according to claim 3 ,
wherein the cosmetic composition is one or more selected from the group consisting of a scalp tonic, a scalp lotion, a scalp cream, a scalp serum, a scalp essence, a scalp ampoule, a scalp treatment, a scalp conditioner, a scalp shampoo, a scalp pack, a hair tonic, a hair lotion, a hair cream, a hair spray, a hair mousse, a hair gel, a hair conditioner, a hair shampoo, a hair conditioning rinse, a hair pack, a hair treatment, an eyebrow growth solution, an eyelash growth solution, an eyelash enhancer, a shampoo for pets, and a conditioner for pets.
6. The method according to claim 1 , wherein the composition is parenterally administered to the subject, or administered via skin of the subject.