IP Library Granted Patent US 11,976,285
Granted Patent B2
US 11,976,285 · App. 16/767,207 · Granted May 7, 2024

Maize gene

Inventors: Xiaohong Yang (Beijing, CN); Jiansheng Li (Beijing, CN); Wenkang Chen (Beijing, CN); Xuan Zhang (Beijing, CN); Lichun Cai (Beijing, CN); Yirong Zhang (Beijing, CN)
Assignee: CHINA AGRICULTURAL UNIVERSITY
C12N15/8218C12N15/8261C07K14/415C12N15/8213C12Q1/6895C12Q2600/13C12Q2600/156C12Q2600/158
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Quick Facts
Patent No.
US 11,976,285
App. No.
16/767,207
Granted
May 7, 2024
Kind
B2
Abstract

Provided herein are KRN2 gene controlling kernel row number in plant, molecular markers closely linked to KRN2 and their application in molecular breeding.

Claims (18)

1. A method of producing a transgenic maize plant having an increased kernel row number compared to a wild type maize plant, comprising obtaining a transgenic maize plant cell comprising a construct that inhibits expression of the KRN2 gene or the gene product thereof, and regenerating a transgenic maize plant comprising the construct from said transgenic maize plant cell.

2. The method according to claim 1 , wherein the expression of the KRN2 gene or the gene product thereof is inhibited by RNA-mediated inhibition of the KRN2 gene.

3. The method according to claim 2 , wherein the construct comprise a polynucleotide encoding a RNA molecule comprising a sequence that is at least 80% complementary to at least 19 continuous nucleotides of the KRN2 gene.

4. A transgenic plant produced by the method of claim 1 .

5. A construct comprising a polynucleotide encoding an inhibitory RNA molecule comprising a sequence that is complementary to the the KRN2 gene, wherein the expression of the construct in a maize plant results in inhibited expression of the KRN2 gene.

6. The construct according to claim 5 , wherein the RNA molecule is selected from the group consisting of an antisense RNA, MiRNA, and siRNA.

7. A transgenic maize plant, maize plant part, or maize plant cell comprising the construct of claim 5 .

8. A commodity product made from the transgenic maize plant, maize plant part, or maize plant cell of claim 7 , wherein the product comprises the construct comprising a polynucleotide encoding an inhibitory RNA molecule comprising a sequence that is complementary to the KRN2 gene.

9. The commodity product of claim 8 , wherein the commodity product is protein concentrate, protein isolate, cereal, meal, flour, biomass.

10. The method according to claim 2 , wherein the construct comprises a polynucleotide encoding a RNA molecule comprising a sequence that is at least 90% continuous nucleotides of the KRN2 gene.

11. The method according to claim 2 , wherein the construct comprises a polynucleotide encoding a RNA molecule comprising a sequence that is 100% complementary to at least 19 continuous nucleotides of the KRN2 gene.

12. The transgenic maize plant of claim 7 , wherein the transgenic maize plant has an increased yield as compared to a wild type maize plant not comprising the construct.

13. The method of claim 1 , wherein the construct is introduced into the maize plant cell by a transformation method.

14. A transgenic maize plant part or plant cell of the transgenic maize plant of claim 4 or a progeny thereof, wherein the transgenic maize plant part or plant cell of the transgenic maize plant or the progeny thereof comprises the construct comprising a polynucleotide encoding an inhibitory RNA molecule comprising a sequence that is complementary to the KRN2 gene.

15. The maize transgenic plant part of claim 14 , wherein the transgenic maize plant part is a transgenic maize seed.

16. The construct of claim 5 , wherein the construct comprises a polynucleotide encoding a RNA molecule comprising a sequence that is at least 90% complementary to at least 19 continuous nucleotides of the KRN2 gene.

17. The construct of claim 5 , wherein the construct comprises a polynucleotide encoding a RNA molecule comprising a sequence that is 100% complementary to at least 19 continuous nucleotides of the KRN2 gene.

18. The transgenic maize plant of claim 7 , wherein the transgenic maize plant has an increased kernel row number relative to a wild type maize plant.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 27, 2020
From: YANG, XIAOHONG; LI, JIANSHENG; CHEN, WENKANG; ZHANG, XUAN; CAI, LICHUN; ZHANG, YIRONG
To: CHINA AGRICULTURAL UNIVERSITY
Reel/Frame 052759/0173 →
Priority Claims (1)
CN 201711217216.3 · Nov 28, 2017 · national
Continuity (1)
Related Publication 20210079410A1 · Mar 18, 2021
Cited By (1)
US 12,600,976