COMPOSITION FOR ENHANCING IMMUNITY OR PREVENTING OR TREATING NEURODEGENERATIVE DISEASES BY USING GOJI BERRIES, MULBERRIES AND JUJUBES
The present invention relates to a composition for enhancing immunity or a composition for preventing or ameliorating neurodegenerative diseases, both of which contain, as an active ingredient, a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof.
1 . A pharmaceutical composition for enhancing immunity comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient.
2 . The pharmaceutical composition for enhancing immunity according to claim 1 , wherein the weight ratio of goji berry:mulberry:jujube is 1 to 3:1 to 3:0.5 to 1.5.
3 . The pharmaceutical composition for enhancing immunity according to claim 1 , wherein the mixture extract or the extract mixture is lyophilized or spray dried.
4 . The pharmaceutical composition for enhancing immunity according to claim 1 , wherein the mixture extract or the extract mixture increases macrophage-derived TNF-α expression.
5 . The pharmaceutical composition for enhancing immunity according to claim 1 , wherein the total concentration of the mixture extract or the extract mixture is 1 μg/ml to 10 mg/ml.
6 . A health functional food for enhancing immunity comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient.
7 . A pharmaceutical composition for preventing or treating neurodegenerative diseases comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient.
8 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to claim 7 , wherein the weight ratio of goji berry:mulberry:jujube is 1 to 3:1 to 3:0.5 to 1.5.
9 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to claim 7 , wherein the mixture extract or the extract mixture is lyophilized or spray dried.
10 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to claim 7 , wherein the mixture extract or the extract mixture increases the ratio of mBDNF (mature BDNF) to hippocampal total BDNF.
11 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to claim 7 , wherein the total concentration of the mixture extract or the extract mixture is 1 μg/ml to 10 mg/ml.
12 . The pharmaceutical composition for preventing or treating neurodegenerative diseases according to claim 7 , wherein the neurodegenerative disease is selected from the group consisting of cerebral infarction, stroke, amnesia, memory impairment, dementia, forgetfulness, Parkinson's disease, Alzheimer's disease, Pick's disease, Creutzfeld-Kacob disease, Huntington's disease, and amyotrophic lateral sclerosis.
13 . A health functional food for preventing or ameliorating neurodegenerative diseases comprising a mixture extract of goji berries, mulberries and jujubes or an extract mixture thereof as an active ingredient.