IP Library › Granted Patent US 12,402,792
Granted Patent B2
US 12,402,792 · App. 16/771,981 · Granted Sep 2, 2025

System and method for determining segments for ablation

Inventors: Clifford Robinson (St. Louis, MO); Phillip Cuculich (St. Louis, MO); Geoffrey Hugo (St. Louis, MO)
Assignee: Washington University
A61B5/0036A61B5/0035A61B5/0044A61B5/055A61B5/364A61B5/7275A61B6/032A61B6/037A61B8/14G16H10/60
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Quick Facts
Patent No.
US 12,402,792
App. No.
16/771,981
Filed
Jun 11, 2020
Granted
Sep 2, 2025
Kind
B2
Art Unit
3798
USPC
600/411
Abstract

Disclosed herein are systems and methods for determining one or more cardiac arrhythmia targets for ablation. The method may include receiving one or more mappings, identifying an abnormality in the one or more mappings, combining the one or more mappings, and defining the one or more cardiac arrhythmia targets based on an overlap of the identified abnormality in the combined one or more mappings.

Claims (41)

1. A method for determining a cardiac arrhythmia target for ablation, the method comprising:

receiving a plurality of mappings of a heart of a patient, the plurality of mappings selected from an electrical mapping, an anatomic mapping, and a functional mapping;

identifying a predetermined number of segments on each mapping of the plurality of mappings, wherein for each mapping the predetermined number of segments encompass the entire mapping, and each segment corresponds to a different area of the heart;

identifying a first abnormality in a first mapping of the plurality of mappings;

selecting any segments of the first mapping in which the first abnormality is located;

identifying a second abnormality in a second mapping of the plurality of mappings;

selecting any segments of the second mapping in which the second abnormality is located;

combining the plurality of mappings;

selecting the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another;

providing the selected cardiac arrhythmia target to a system operable to carry out ablation of the selected cardiac arrhythmia target; and

performing ablation on the patient based on the received selected cardiac arrhythmia target.

2. The method of claim 1 , wherein identifying the first abnormality comprises identifying one or more contours on the first mapping that includes the first abnormality.

3. The method of claim 1 , wherein identifying the first abnormality comprises receiving a manual identification of the first abnormality from a user.

4. The method of claim 1 , wherein selecting the cardiac arrhythmia target comprises selecting the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and additional data about the patient.

5. The method of claim 1 , wherein ablating the cardiac arrhythmia target comprises non-invasive ablation of the cardiac arrhythmia target.

6. The method of claim 1 , further comprising weighting each mapping of the received plurality of mappings, and wherein selecting the cardiac arrhythmia target comprises selecting the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and the weighting of the received plurality of mappings.

7. The method of claim 1 , further comprising determining a confidence score of the combined mappings, and wherein selecting the cardiac arrhythmia target comprises selecting the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and the confidence score.

8. The method of claim 1 , wherein the electrical mapping is an electrocardiograph image, the anatomic mapping is at least one of a computer tomography image or a magnetic resonance image, and the functional mapping is at least one of a photo emission computed tomographic image, a positron emission tomography image or an echocardiogram image.

9. The method of claim 1 , further comprising generating a decision support module.

10. The method of claim 9 , wherein the decision support module comprises an output of the cardiac arrhythmia target and one or more of a description of a scar pattern, a description of a scar burden size and location, a suggested volume to achieve ablation, a confidence score of the combined mappings, a listing of at-risk structures, a general recommendation, an expected success rate with non-invasive therapy, or an expected success rate with alternative treatment modalities.

11. The method of claim 1 , wherein selecting the cardiac arrhythmia target comprises selecting the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and additional data from previous patients.

12. At least one non-transitory computer readable medium storing instructions which when executed by at least one processor, cause the at least one processor to:

receive a plurality of mappings of a heart of a patient, the plurality of mappings selected from an electrical mapping, an anatomic mapping, and a functional mapping;

identify a predetermined number of segments on each mapping of the plurality of mappings, wherein for each mapping, the predetermined number of segments encompass the entire mapping, and each segment corresponds to a different are of the heart of the patient;

identify first abnormality in a first mapping of the plurality of mappings;

select any segments of the first mapping in which the first abnormality is located;

identify a second abnormality in a second mapping of the plurality of mappings;

select any segments of the second mapping in which the second abnormality is located;

combine the plurality of mappings;

select a cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another;

provide the selected cardiac arrhythmia target to a system operable to carry out ablation of the selected cardiac arrhythmia target; and

perform ablation on the patient based on the received selected cardiac arrhythmia target.

13. The at least one non-transitory computer readable medium of claim 12 , further comprising instructions, which when executed by the at least one processor, cause the at least one processor to select the cardiac arrhythmia target for ablation based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and additional data about the patient.

14. The at least one non-transitory computer readable medium of claim 12 , further comprising instructions, which when executed by the at least one processor, cause the at least one processor to weight each mapping of the received plurality of mappings, and to select the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and the weighting of the received plurality of mappings.

15. The at least one non-transitory computer readable medium of claim 12 , further comprising instructions, which when executed by the at least one processor, cause the at least one processor to determine a confidence score of the combined mappings, and select the cardiac arrhythmia target based on any segments in the combined plurality of mappings in which selected segments containing the identified first abnormality and selected segments containing the identified second abnormality overlap one another, and the confidence score.

16. The at least one non-transitory computer readable medium of claim 12 , wherein the electrical mapping is an electrocardiograph image, the anatomic mapping is at least one of a computer tomography image or a magnetic resonance image, and the functional mapping is at least one of a photo emission computed tomographic image, a positron emission tomography image or an echocardiogram image.

17. The at least one non-transitory computer readable medium of claim 12 , further comprising instructions, which when executed by the at least one processor, cause the at least one processor to:

receive one or more clinical mappings including at least one of demographics, surgical history, information about ventricular tachycardia and prior electroanatomical mappings; and

determine an updated cardiac arrhythmia target for ablation based on the combined plurality of mappings and the one or more clinical mappings.

18. The at least one non-transitory computer readable medium of claim 12 , further comprising instructions, which when executed by the at least one processor, cause the at least one processor to generate a decision support module.

19. The at least one non-transitory computer readable medium of claim 18 , wherein the decision support module comprises an output of the cardiac arrhythmia target and one or more of a description of a scar pattern, a description of a scar burden size and location, a suggested volume to achieve ablation, a confidence score of the combined mappings, a listing of at-risk structures, a general recommendation, an expected success rate with non-invasive therapy, or an expected success rate with alternative treatment modalities.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 15, 2020
From: ROBINSON, CLIFFORD; CUCULICH, PHILLIP; HUGO, GEOFFREY
To: WASHINGTON UNIVERSITY
Reel/Frame 052940/0032 →
Continuity (3)
Provisional Application 62607084 · Dec 18, 2017
Provisional Application 62598162 · Dec 13, 2017
Related Publication 20210137384A1 · May 13, 2021
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