IP Library Granted Patent US 11,311,237
Granted Patent B2
US 11,311,237 · App. 16/775,256 · Granted Apr 26, 2022

Systems and methods for computationally efficient non-invasive blood quality measurement

Inventors: Elad Ferber (Los Altos Hills, CA); Andrew Joseph DeKelaita (Belmont, CA); Patrick Edward Landreman (Palo Alto, CA)
A61B5/681A61B5/0004A61B5/02427A61B5/08A61B5/7203A61B5/7221A61B5/7264A61B5/7275
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Quick Facts
Patent No.
US 11,311,237
App. No.
16/775,256
Granted
Apr 26, 2022
Kind
B2
Abstract

In some embodiments, a system comprises a wearable member configured to receive first energy, generate first signals, select a first subset of the time series data, determine a standard deviation indicating a quality at a low percentile of values associated with first windows of the time series data and a high percentile of values associated with the first windows of the time series data, the signal assessment threshold being including at least the values of the lower percentile, receive second energy, generate second signals containing second time series data from the second energy, select a second subset of the time series data to assess, compare all or part of the second signals to the signal assessment threshold, and if all or part of the second signals include the second time series data that is within the values of the lower percentile, then remove the second signals from further processing.

Claims (110)

1. A method comprising:

receiving, from a wearable sensor device, a first energy from at least one light emitting diode (LED) of the wearable sensor device, the first energy being at a wavelength to take a physiological measurement;

generating, by the wearable sensor device, first signals containing first time series data from the first energy;

selecting, by the wearable sensor device, a first subset of the first time series data to generate a signal assessment threshold;

determining a standard deviation indicating a quality of the signal assessment threshold at a low percentile of values associated with a first window of the first time series data and at a high percentile of values associated with the first window of the first time series data, the signal assessment threshold being including at least the values of the lower percentile;

receiving, from the wearable sensor device, a second energy from the at least one LED of the wearable sensor device, the second energy being at the wavelength to take the physiological measurement of a first wearer of the wearable sensor device;

generating, by the wearable sensor device, second signals containing second time series data from the second energy;

selecting a second subset of the second time series data to assess prior to processing the second time series data of the second subset and other second time series data taken near or at a same time as the generation of the second signals;

comparing all or part of the second signals to the signal assessment threshold;

if all or part of the second signals include the second time series data that is within the values of the lower percentile based on the signal assessment threshold, then removing the second signals from further processing; and

determining a photoplethysmogram signal of a user based on the signals.

2. The method of claim 1 , wherein if all or part of the second signals include second time series data that is within the values of the upper percentile based on the signal assessment threshold, then removing the second signals from further processing.

3. The method of claim 1 , wherein if all or part of the second signals include second time series data that is not within the values of the upper percentile and not within the values of the lower percentile based on the signal assessment threshold, then processing the second signals to take the physiological measurement.

4. The method of claim 1 , wherein the physiological measurement is a respiratory rate.

5. The method of claim 1 , wherein the physiological measurement is a Sp02 measurement.

6. The method of claim 1 , wherein the first energy is taken of a second wearer of the wearable sensor device.

7. The method of claim 1 , wherein if all or part of the second signals include the second time series data that is above the values of the lower percentile based on the signal assessment threshold, then processing the second signals to make measurements.

8. The method of claim 1 , wherein if all or part of the second signals include the second time series data that is above the values of the lower percentile based on the signal assessment threshold, then processing third signals to make measurements, the third signals being generated by a location of the first wearer associated with a low signal-to-noise ratio (SNR).

9. The method of claim 1 , wherein determining the standard deviation indicating the quality of the signal assessment threshold at the low percentile of values associated with the first window of the first time series data and the high percentile of values associated with the first window of the first time series data comprises computing a normalized standard deviation of the first window:

σ

s

=

1

N

Σ

i

(

x

i

-

x

)

2

x

Where:

x

=

1

N

i

x

i

.

10. A system comprising:

a wearable member including a processor and a memory to store executable instructions, the instructions being executable to:

receive a first energy from at least one light emitting diode (LED) of a wearable sensor device, the first energy being at a wavelength to take a physiological measurement;

generate first signals containing first time series data from the first energy;

select a first subset of the first time series data to generate a signal assessment threshold;

determine a standard deviation indicating a quality of the signal assessment threshold at a low percentile of values associated with a first window of the first time series data and at a high percentile of values associated with the first window of the first time series data, the signal assessment threshold being including at least the values of the lower percentile;

receive a second energy from the at least one LED of the wearable sensor device, the second energy being at the wavelength to take the physiological measurement of a first wearer of the wearable sensor device;

generate second signals containing second time series data from the second energy;

select a second subset of the second time series data to assess prior to processing the second time series data of the second subset and other second time series data taken near or at a same time as the generation of the second signals;

compare all or part of the second signals to the signal assessment threshold;

if all or part of the second signals include the second time series data that is within the values of the lower percentile based on the signal assessment threshold, then remove the second signals from further processing; and

determine a photoplethysmogram signal of a user based on the signals.

11. The system of claim 10 , wherein if all or part of the second signals include second time series data that is within the values of the upper percentile based on the signal assessment threshold, then remove the second signals from further processing.

12. The system of claim 10 , wherein if all or part of the second signals include second time series data that is not within the values of the upper percentile and not within the values of the lower percentile based on the signal assessment threshold, then process the second signals to take the physiological measurement.

13. The system of claim 10 , wherein the physiological measurement is a respiratory rate.

14. The system of claim 10 , wherein the physiological measurement is a Sp02 measurement.

15. The system of claim 10 , wherein the first energy is taken of a second wearer of the wearable sensor device.

16. The system of claim 10 , wherein if all or part of the second signals include the second time series data that is above the values of the lower percentile based on the signal assessment threshold, then process the second signals to make measurements.

17. The system of claim 10 , wherein if all or part of the second signals include the second time series data that is above the values of the lower percentile based on the signal assessment threshold, then process the third signals to make measurements, the third signals being generated by a location of the first wearer associated with a low signal-to-noise ratio (SNR).

18. The system of claim 10 , wherein determining the standard deviation indicating the quality of the signal assessment threshold at the low percentile of values associated with the first window of the first time series data and the high percentile of values associated with the first window of the first time series data comprises computing a normalized standard deviation of the first window:

σ

s

=

1

N

Σ

i

(

x

i

-

x

)

2

x

Where:

x

=

1

N

i

x

i

.

19. A system comprising:

a processor; and

a memory storing instructions that, when executed by the processor, cause the processor to:

receive a first energy from at least one light emitting diode (LED) of a wearable sensor device, the first energy being at a wavelength to take a physiological measurement;

generate first signals containing first time series data from the first energy;

select a first subset of the first time series data to generate a signal assessment threshold;

determine a standard deviation indicating a quality of the signal assessment threshold at a low percentile of values associated with a first window of the first time series data and at a high percentile of values associated with the first window of the first time series data, the signal assessment threshold being including at least the values of the lower percentile;

receive a second energy from the at least one LED of the wearable sensor device, the second energy being at the wavelength to take the physiological measurement of a first wearer of the wearable sensor device;

generate second signals containing second time series data from the second energy;

select a second subset of the second time series data to assess prior to processing the second time series data of the second subset and other second time series data taken near or at a same time as the generation of the second signals;

compare all or part of the second signals to the signal assessment threshold;

if all or part of the second signals include the second time series data that is within the values of the lower percentile based on the signal assessment threshold, then remove the second signals from further processing; and

determine a photoplethysmogram signal of a user based on the signals.

Assignments (8)
CORRECTIVE ASSIGNMENT TO CORRECT THE SPELLING OF INVENTORS LAST NAME PREVIOUSLY RECORDED ON REEL 057234 FRAME 0563. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 13, 2023
From: DEKELAITA, ANDREW
To: ECHO LABS, INC.
Reel/Frame 064589/0021 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 30, 2021
From: ITAMAR MEDICAL, LTD.
To: ITAMAR MEDICAL SPRY 2021, LIMITED PARTNERSHIP
Reel/Frame 057326/0340 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 23, 2021
From: SPRY HEALTH, INC.
To: ITAMAR MEDICAL LTD.
Reel/Frame 057259/0451 →
CHANGE OF NAME Recorded Aug 23, 2021
From: ECHO LABS, INC.
To: SPRY HEALTH, INC.
Reel/Frame 057266/0527 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 20, 2021
From: FERBER, ELAD
To: ECHO LABS, INC.
Reel/Frame 057241/0666 →
CHANGE OF NAME Recorded Aug 20, 2021
From: ECHO LABS, INC.
To: SPRY HEALTH, INC.
Reel/Frame 057252/0468 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2021
From: DEKALAITA, ANDREW
To: ECHO LABS, INC.
Reel/Frame 057234/0563 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 19, 2021
From: LANDREMAN, PATRICK
To: ECHO LABS, INC.
Reel/Frame 057234/0538 →
Continuity (3)
Provisional Application 62797909 · Jan 28, 2019
Provisional Application 62797912 · Jan 28, 2019
Related Publication 20200237303A1 · Jul 30, 2020