IP Library Granted Patent US 10,901,059
Granted Patent B1
US 10,901,059 · App. 16/779,376 · Granted Jan 26, 2021

Multi-shot diffusion-weighted MRI reconstruction using unrolled network with U-net as priors

Inventors: Yuxin Hu (Stanford, CA); Brian A. Hargreaves (Menlo Park, CA)
Assignee: The Board of Trustees of the Leland Stanford Junior University
G01R33/5608G01R33/4818G01R33/56341
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 10,901,059
App. No.
16/779,376
Granted
Jan 26, 2021
Kind
B1
Abstract

A method of magnetic resonance imaging performs a scan by a magnetic resonance imaging system to acquire k-space data; applies the k-space data as input to an unrolled convolutional neural network comprising multiple iterations, and generates reconstructed images from the output of the unrolled convolutional neural network by combining images from different shots. Each iteration of the unrolled network performs a first gradient update, applies the result to a first U-net in k-space, performs a second gradient update, and applies a second U-net in image space. The first gradient update and the second gradient update are based on a theoretical gradient from a physical measurement model.

Claims (13)

1. A method of magnetic resonance imaging comprising:

a) performing a scan by a magnetic resonance imaging system to acquire k-space data;

b) applying the k-space data as input to an unrolled convolutional neural network comprising multiple iterations, wherein each iteration comprises:

i) performing a first gradient update,

ii) applying a first U-net in k-space,

iii) performing a second gradient update, and

iv) applying a second U-net in image space;

wherein the first gradient update and the second gradient update are based on a theoretical gradient from a physical measurement model; and

c) generating reconstructed images from the output of the unrolled convolutional neural network by combining images from different shots.

2. The method of claim 1 wherein the physical measurement model comprises a receiving coil sensitivity map and a data sampling pattern.

3. The method of claim 1 wherein the scan is a multi-shot diffusion weighted scan.

4. The method of claim 1 wherein the first U-net and second U-net include skip connections.

5. The method of claim 1 wherein the first U-net and second U-net include res-nets.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 25, 2020
From: HU, YUXIN; HARGREAVES, BRIAN A.
To: THE BOARD OF TRUSTEES OF THE LELAND STANFORD JUNIOR UNIVERSITY
Reel/Frame 051926/0799 →
CONFIRMATORY LICENSE Recorded Feb 7, 2020
From: STANFORD UNIVERSITY
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 051846/0463 →
Cited By (1)
US 12,260,549