IP Library Granted Patent US 11,475,996
Granted Patent B2
US 11,475,996 · App. 16/785,380 · Granted Oct 18, 2022

Systems and methods for determination of patient true state for personalized medicine

Inventors: Darren Matthew Schulte (San Francisco, CA); John O. Schneider (Los Gatos, CA); Robert Derward Rogers (Oakland, CA); Vishnuvyas Sethumadhavan (Mountain View, CA)
Assignee: Apixio, Inc.
G16H50/20G16H10/60G16H20/10G16H50/50G16Z99/00G16H40/20
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Quick Facts
Patent No.
US 11,475,996
App. No.
16/785,380
Granted
Oct 18, 2022
Kind
B2
Abstract

Systems and methods for personalizing medicine utilizing the true state of the patient are provided. A number of medical records for a patient are subjected to predictive modeling for various conditions (known as patient ‘true state’). The patient personal information, previous care, and true state may be provided into a state machine in order to determine the resources needed for the patient. The medical resources may be any of laboratory services, diagnostics, therapies and medications. Using the true state information, and number of activities may be performed for the patient based upon the patient's needs. These activities include scheduling lab or diagnostic procedures in advance of an appointment, filling in documentation gaps, identifying items that require additional documentation using the true state, and tracking follow-up. It may also be beneficial to validate the true state.

Claims (30)

1. A computer-implemented method for personalizing medical care in a health information management system, the computer-implemented method comprising:

determining and extracting terms in a plurality of medical records associated with a patient by parsing and analyzing the plurality of medical records;

transforming the terms extracted from the plurality of medical records into a standardized and structured data set, wherein the data set includes hyperlinks to the plurality of medical records to facilitate real-time reference from the structured data set back to the plurality of medical records;

clustering the terms into medical concept data based at least in part upon machine learned rules;

inferring a true state for the patient based upon the medical concept data, wherein the true state is inferred using a processor implementing at least one probabilistic model, and wherein the true state comprises at least one condition of the patient;

validating the true state including optimizing routing of evidence for validation based upon greatest impact the evidence has on the true state inference; and

determining at least one medical resource for the patient based upon the true state.

2. The computer-implemented method of claim 1 further comprising generating a confidence level for the inferred true state.

3. The computer-implemented method of claim 1 wherein the medical resources include any of laboratory services, diagnostics, therapies and medications.

4. The computer-implemented method of claim 1 further comprising scheduling lab or diagnostic procedures in advance of an appointment based upon the true state.

5. The computer-implemented method of claim 1 further comprising filling documentation gaps using the true state.

6. The computer-implemented method of claim 1 wherein the validation updates a predictive model and updates a confidence level for the inferred true state.

7. A health information management system for personalizing medical care comprising:

a network interface in communication with a first pass analyzer, the network interface configured to receive a plurality of medical records for a patient; and

the first pass analyzer including a processor and configured to:

determine and extract terms in a plurality of medical records associated with a patient by parsing and analyzing the plurality of medical records;

transform the terms extracted from the plurality of medical records into a standardized and structured data set, wherein the data set includes hyperlinks to the plurality of medical records to facilitate real-time reference from the structured data set back to the plurality of medical records;

cluster the terms into medical concept data based at least in part upon machine learned rules;

infer a true state for the patient based upon the medical concept data, wherein the true state is inferred based upon at least one probabilistic model, and wherein the true state comprises at least one condition of the patient;

validate the true state including optimizing routing of evidence for validation based upon greatest impact the evidence has on the true state inference; and

determine at least one medical resource for the patient based upon the true state.

8. The system of claim 7 wherein the first pass analyzer is further configured to generate a confidence level for the inferred true state.

9. The system of claim 7 wherein the medical resources include any of laboratory services, diagnostics, therapies and medications.

10. The system of claim 7 wherein the first pass analyzer is further configured to schedule lab or diagnostic procedures in advance of an appointment based upon the true state.

11. The system of claim 7 wherein the first pass analyzer is further configured to fill documentation gaps using the true state.

12. The system of claim 7 wherein the first pass analyzer is further configured to identify items that require additional documentation using the true state.

13. The system of claim 7 wherein the first pass analyzer is further configured to track follow-up.

14. The system of claim 7 wherein validating the true state includes updating a predictive model and updating a confidence level for the inferred true state.

15. The computer-implemented method of claim 1 , further comprising automatically scheduling the medical resources for the patient.

16. The computer-implemented method of claim 1 , further comprising storing the true state for the patient with a plurality of true states for a plurality of patients, wherein the true states for the plurality of patients are analyzed for profiling.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE ASSIGNEE NAME PREVIOUSLY RECORDED AT REEL: 53308 FRAME: 738. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Dec 11, 2024
From: SCHULTE, DARREN MATTHEW; SCHNEIDER, JOHN O.; ROGERS, ROBERT DERWARD; SETHUMADHAVAN, VISHNUVYAS
To: APIXIO INC.
Reel/Frame 069599/0569 →
RELEASE OF SECURITY INTEREST Recorded Aug 30, 2024
From: CHURCHILL AGENCY SERVICES LLC
To: APIXIO, LLC (F/K/A APIXIO INC.)
Reel/Frame 068453/0713 →
ENTITY CONVERSION Recorded Jul 12, 2023
From: APIXIO INC.
To: APIXIO, LLC
Reel/Frame 064259/0006 →
SECURITY INTEREST Recorded Jun 13, 2023
From: APIXIO INC.
To: CHURCHILL AGENCY SERVICES LLC
Reel/Frame 063928/0847 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 24, 2020
From: SCHULTE, DARREN MATTHEW; SCHNEIDER, JOHN O.; ROGERS, ROBERT DERWARD; SETHUMADHAVAN, VISHNUVYAS
To: APIXIO, INC.
Reel/Frame 053308/0738 →
Continuity (10)
Continuation 14672208 · Mar 29, 2015
Continuation In Part 14538798 · Nov 11, 2014
Continuation In Part 14498594 · Sep 26, 2014
Continuation In Part 13656652 · Oct 19, 2012
Continuation In Part 13223228 · Aug 31, 2011
Provisional Application 62059139 · Oct 2, 2014
Provisional Application 61883967 · Sep 27, 2013
Provisional Application 61682217 · Aug 11, 2012
Provisional Application 61379228 · Sep 1, 2010
Related Publication 20200251216A1 · Aug 6, 2020