IP Library Granted Patent US 11,209,776
Granted Patent B2
US 11,209,776 · App. 16/816,949 · Granted Dec 28, 2021

Birefringent lens interferometer for use in microscopy and other applications

Inventors: Gary Brooker (Rockville, MD); Nisan Siegel (Silver Spring, MD)
Assignee: CELLOPTIC, INC.
G03H1/041A61B3/13G02B1/02G02B3/08G02B5/3016G02B5/3083G02B21/0056G02B21/0068G03H1/0005G03H1/0443G03H1/06G03H1/0866G03H2001/005G03H2001/0447G03H2001/0452G03H2222/24G03H2223/17G03H2223/20
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Quick Facts
Patent No.
US 11,209,776
App. No.
16/816,949
Granted
Dec 28, 2021
Kind
B2
Abstract

Techniques to improve image quality in holography utilizing lenses made from materials with non-quantized anisotropic electromagnetic properties, such as birefringent materials, to advantageously split an incoming beam of light into two coincident beams with different focal lengths that interfere with one another and thus create holograms free of electro-optical or pixelated devices are disclosed for microscopy and other applications. The use of thin birefringent lenses and single crystal alpha-BBO lenses are introduced. Corresponding systems, methods and apparatuses are described.

Claims (17)

1. An optical apparatus, comprising:

a plurality of optical elements including at least one thin birefringent component, wherein the plurality of optical elements are configured to:

receive electromagnetic radiation from an object, wherein the electromagnetic radiation is incoherent light;

transform, by transmission using the at least one thin birefringent component, the received electromagnetic radiation to generate two or more differentially modulated electromagnetic waves propagating in a common path without overall optical path difference and phase shift between the differentially modified electromagnetic waves other than a desired geometric optical path difference; and

provide for the differentially modulated electromagnetic waves to create electromagnetic interference;

wherein the optical apparatus does not include a birefringent optical element to compensate for overall optical path difference or phase shift between the differentially modified electromagnetic waves, and wherein the optical apparatus does not include any spatial light modulator.

2. The apparatus of claim 1 , wherein the at least one thin birefringent component includes a birefringent Fresnel lens made with solid crystalline material or liquid crystalline material.

3. The apparatus of claim 1 , wherein the at least one thin birefringent component includes a patterned birefringent solid or liquid crystalline material.

4. The apparatus of claim 1 , wherein the at least one thin birefringent component includes a nano-structured non-birefringent material, wherein the birefringent properties of the component are imparted by the patterns encoded in the nano-structures.

5. The apparatus of claim 4 , wherein the at least one thin birefringent component encodes one or more spherical quadratic phase patterns.

6. The apparatus of claim 4 , wherein the at least one thin birefringent component encodes one or more phase patterns other than spherical quadratic phase patterns.

7. The apparatus of claim 4 , wherein the at least one thin birefringent component simultaneously encodes one or more spherical quadratic phase patterns and one or more phase patterns that are not spherical quadratic phase patterns.

8. The apparatus of claim 4 , wherein the at least one thin birefringent component encodes one or more phase patterns other than spherical quadratic phase patterns, and does not encode any spherical quadratic pattern.

9. The apparatus of claim 1 , wherein the at least one thin birefringent component encodes one or more spherical quadratic phase patterns.

10. The apparatus of claim 9 , wherein the at least one thin birefringent component encodes one or more phase patterns other than spherical quadratic phase patterns.

11. The apparatus of claim 1 , wherein the at least one thin birefringent component simultaneously encodes one or more spherical quadratic phase patterns and one or more phase patterns that are not spherical quadratic phase patterns.

12. The apparatus of claim 1 , wherein the at least one thin birefringent component encodes one or more phase patterns other than spherical quadratic phase patterns, and does not encode any spherical quadratic phase phase pattern.

Assignments (2)
CONFIRMATORY LICENSE Recorded Jan 22, 2024
From: CELLOPTIC INC
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 066360/0652 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 12, 2020
From: BROOKER, GARY; SIEGEL, NISAN
To: CELLOPTIC, INC.
Reel/Frame 052099/0397 →
Continuity (7)
Continuation 15588096 · May 5, 2017
Continuation In Part 15455863 · Mar 10, 2017
Continuation In Part 15228386 · Aug 4, 2016
Continuation In Part PCTUS2015028477 · Apr 30, 2015
Provisional Application 62332857 · May 6, 2016
Provisional Application 61987205 · May 1, 2014
Related Publication 20200241472A1 · Jul 30, 2020