IP Library Granted Patent US 11,278,642
Granted Patent B2
US 11,278,642 · App. 16/823,175 · Granted Mar 22, 2022

Bioimplant with evanescent coating film

Inventors: Takao Hotokebuchi (Fukuoka, JP); Iwao Noda (Osaka, JP)
Assignees: TAKAO HOTOKEBUCHI; KYOCERA CORPORATION
A61L27/32A61L27/06A61L27/306A61L27/425A61L27/54A61L2300/104A61L2300/404A61L2300/606A61L2420/02A61L2420/04A61L2430/24
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Quick Facts
Patent No.
US 11,278,642
App. No.
16/823,175
Granted
Mar 22, 2022
Kind
B2
Abstract

To provide a bioimplant capable of controlling a rate of an antibacterial agent and an antibiotic to be eluted from the coating film. An evanescent coating film made of a calcium phosphate-based material having crystallinity of 10% to 90% is formed at a predetermined area of the bioimplant and an antibacterial agent or an antibiotic is contained in the coating film to suppress adhesion of bacteria.

Claims (33)

1. A bioimplant, comprising:

an implant comprising a stem portion and a neck portion; and

an evanescent coating film comprising a calcium phosphate-based material formed on a first surface of the stem portion by thermal spraying,

wherein the evanescent coating film comprises a silver material distributed in the evanescent coating film, has a thickness in the range of 5 micrometers to 100 micrometers, and has a crystallinity in the range of 10% to 90% and

wherein an evanescence period of the evanescent coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of the thickness and the crystallinity of the evanescent coating film.

2. The bioimplant of claim 1 , wherein the evanescent coating film is not disposed on a surface of the neck portion.

3. The bioimplant of claim 2 , wherein the evanescent coating film does not cover a second surface of the stem portion, wherein the first and second surfaces laterally surround a portion of the stem.

4. The bioimplant of claim 1 , wherein the calcium phosphate-based material has a crystallinity of 60% to 90%.

5. The bioimplant of claim 1 , wherein a thickness of the evanescent coating film is in the range of 50 to 100 micrometers (μm).

6. The bioimplant of claim 1 , wherein the thickness of the evanescent coating film is in the range of 20 and 40 micrometers (μm).

7. The bioimplant of claim 1 , wherein an elution period of the silver material when the implant is placed in a body fluid is at least six months.

8. A bioimplant, comprising:

an implant comprising a metal or metal alloy material; and

an evanescent coating film comprising a calcium phosphate-based material formed on a first surface of the implant by thermal spraying,

wherein the evanescent coating film comprises silver metal particles distributed in the evanescent coating film, has a crystallinity in the range of 10% to 90%, and has a thickness in the range of 5 to 100 micrometers (μm), and

wherein an evanescence period of the evanescent coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of the thickness and the crystallinity of the evanescent coating film.

9. The bioimplant of claim 8 , wherein the thickness of the evanescent coating film is in the range of 20 and 40 micrometers (μm).

10. The bioimplant of claim 8 , wherein the implant comprises a stem portion and a neck portion, and the evanescent coating film is not disposed on a surface of the neck portion.

11. The bioimplant of claim 10 , wherein the implant comprises a stem portion and a neck portion, and the evanescent coating film does not cover a second surface of the stem portion, wherein the first and second surfaces laterally surround a portion of the stem.

12. The bioimplant of claim 8 , wherein the calcium phosphate-based material has a crystallinity of 60% to 90%.

13. The bioimplant of claim 8 , wherein an elution period of the silver metal particles when the implant is placed in a body fluid is at least six months.

14. A bioimplant, comprising:

an implant comprising a stem portion and a neck portion;

an evanescent coating film comprising a calcium phosphate-based material and a silver material formed on a first surface of the stem portion by thermal spraying; and

a shell configured to receive the neck portion therein, the shell comprising an upper hemispherical surface,

wherein the evanescent coating film covers the upper hemispherical surface,

wherein the calcium phosphate-based material has a crystallinity of 10% to 90%,

wherein the evanescent coating film has a thickness in the range of 5 and 100 micrometers (μm), and

wherein an evanescence period of the evanescent coating film is configured to be a predetermined period in the range of 6 weeks to 120 months by selecting a combination of the thickness and the crystallinity of the evanescent coating film.

15. The bioimplant of claim 14 , wherein the evanescent coating film is not disposed on a surface of the neck portion.

16. The bioimplant of claim 15 , wherein the evanescent coating film does not cover a second surface of the stem portion, wherein the first and second surfaces laterally surround a portion of the stem.

17. The bioimplant of claim 14 , wherein the thickness of the evanescent coating film is in the range of 20 and 40 micrometers (μm).

18. The bioimplant of claim 14 , wherein the calcium phosphate-based material has a crystallinity of 60% to 90%.

Assignments (2)
NUNC PRO TUNC ASSIGNMENT Recorded Jun 15, 2026
From: KYOCERA CORPORATION
To: KYOCERA MEDICAL CORPORATION
Reel/Frame 074947/0956 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 14, 2023
From: NODA, IWAO
To: KYOCERA CORPORATION
Reel/Frame 064903/0738 →
Priority Claims (2)
JP JP2006-244479 · Sep 8, 2006 · national
JP JP2006-252933 · Sep 19, 2006 · national
Continuity (3)
Continuation 16017309 · Jun 25, 2018
Continuation In Part 12440430
Related Publication 20200215230A1 · Jul 9, 2020
Cited By (1)
US 12,226,550