IP Library › Granted Patent US 11,737,734
Granted Patent B2
US 11,737,734 · App. 16/849,958 · Granted Aug 29, 2023

Ultrasound imaging device and system, and image enhancement method for contrast enhanced ultrasound imaging

Inventors: Xirui Zhang (Beijing, CN); Jie Tang (Beijing, CN); Yukun Luo (Beijing, CN); Mingbo Zhang (Beijing, CN); Maodong Sang (Beijing, CN); Lanxi Xiang (Shenzhen, CN); Donghai Qin (Shenzhen, CN); Wei Fan (Shenzhen, CN)
Assignees: BEIJING SHEN MINDRAY MED ELEC TECH RES INST CO LTD; GENERAL HOSPITAL OF CHINESE PLA; SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
A61B8/481G06T5/007G06T5/50G06T7/0012A61B8/5207G06T2207/10132G06T2207/20056
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Quick Facts
Patent No.
US 11,737,734
App. No.
16/849,958
Granted
Aug 29, 2023
Kind
B2
Abstract

An ultrasound imaging device and system, and an image enhancement method for ultrasound radiography and imaging. Image enhancement coefficients of location points in a examined biological tissue are computed first according to radiography channel data, and then, weighted processing is performed on the image enhancement coefficients and beam forming data.

Claims (71)

1. An image enhancement method for contrast enhanced ultrasound imaging, comprising:

obtaining contrast-enhanced channel data, wherein, an ultrasound probe is configured to transmit ultrasound waves to an examined biological tissue containing contrast agents and receive ultrasound echo signals to obtain the contrast-enhanced channel data, each receiving element of multiple receiving elements of the ultrasound probe is configured to receive the ultrasound echo signals to obtain a piece of the contrast-enhanced channel data, the multiple receiving elements of the ultrasound probe are configured to receive the ultrasound echo signals to obtain multiple pieces of the contrast-enhanced channel data, and the contrast-enhanced channel data corresponding to one location point in the biological tissue;

calculating an image enhancement coefficient at the one location point in the examined biological tissue according to the contrast-enhanced channel data, the image enhancement coefficient being indicative of correlations among the multiple pieces of the contrast-enhanced channel data corresponding to the multiple receiving elements;

performing a beam-forming on the contrast-enhanced channel to obtain a beam-formed data at the one location point; and

performing weighting processing on the image enhancement coefficient and the beam-formed data to obtain contrast-enhanced image data corresponding to the one location point in the examined biological tissue.

2. The method of claim 1 , wherein calculating the image enhancement coefficient at the one location point in the examined biological tissue according to the contrast-enhanced channel data comprises:

calculating a correlation between each piece of the contrast-enhanced channel data, and determining the image enhancement coefficient according to the correlations.

3. The method of claim 2 , wherein calculating the correlation between each piece of the contrast-enhanced channel data comprises:

performing an envelope detection on each piece of the contrast-enhanced channel data to obtain envelope data, and calculating the correlation between each piece of the contrast-enhanced channel data according to the envelope data, wherein the envelope detection comprises an envelope detection at a power; or

calculating the correlation between each piece of the contrast-enhanced channel data directly using the contrast-enhanced channel data; or

performing a phase detection on each piece of the contrast-enhanced channel data to obtain phase data, and calculating the correlation between each piece of the contrast-enhanced channel data according to the phase data; or

performing a Fourier transform on each piece of the contrast-enhanced channel data to obtain frequency domain data, and calculating the correlation between each piece of the contrast-enhanced channel data according to the frequency domain data.

4. The method of claim 1 , wherein performing the weighting processing on the image enhancement coefficient and the beam-formed data comprises: multiplying the image enhancement coefficient and the beam-formed data corresponding to the one location point.

5. The method of claim 1 , further comprising: after obtaining the contrast-enhanced channel data, performing time delay processing on the contrast-enhanced channel data.

6. The method of claim 1 , further comprising: before obtaining the contrast-enhanced channel data:

performing time delay processing on the ultrasound echo signals to obtain time-delayed data; and

extracting contrast-enhanced channel data representing contrast agent information from the time-delayed data.

7. The method of claim 1 , wherein performing the weighting processing on the image enhancement coefficient and the beam-formed data to obtain the contrast-enhanced image data corresponding to the one location point in the examined biological tissue comprises:

performing the weighting processing on the image enhancement coefficient and the beam-formed data to obtain weighted image data comprising multiple weighted images respectively corresponding to multiple angles of using the ultrasound probe; and

performing coherent compound processing on the multiple weighted images to obtain the contrast-enhanced image data by compounding the multiple weighted images.

8. The method of claim 7 , wherein,

obtaining the contrast-enhanced channel data using the ultrasound probe comprises:

obtaining contrast-enhanced channel data corresponding to the multiple angles of using the ultrasound probe, wherein, the contrast-enhanced channel data corresponding to the multiple angles are derived from ultrasound echo signals of the ultrasound waves transmitted to the examined biological tissue by the ultrasound probe in the multiple angles, and, when transmitting in each angle of the multiple angles, the multiple receiving elements of the ultrasound probe are configured to receive the ultrasound echo signals corresponding to an angle of the multiple angles to obtain multiple pieces of the contrast-enhanced channel data corresponding to the one location point in the examined biological tissue in the angle; and

performing the weighting processing on the image enhancement coefficient and the beam-formed data to obtain the weighted image data and performing the coherent compound processing on the multiple weighted images to obtain the contrast-enhanced image data comprises:

obtaining the image enhancement coefficient and the beam-formed data corresponding to the one location point in the angle according to the contrast-enhanced channel data corresponding to the one location point in the angle, performing the weighting processing on the image enhancement coefficient and the beam-formed data corresponding to the one location point in the angle to obtain a weighted image corresponding to the one location point in the angle, obtaining the multiple weighted images corresponding to the multiple angles, and performing the coherent compound processing on the multiple image data corresponding to the multiple angles to obtain the contrast-enhanced image data by compounding the multiple weighted images.

9. An image enhancement method for contrast enhanced ultrasound imaging, comprising:

transmitting ultrasound waves to a region of interest containing contrast agents;

receiving echoes of the ultrasound waves to obtain echo signals;

extracting contrast-enhanced channel data according to the echo signals, wherein multiple pieces of the contrast-enhanced channel data corresponding to one time point are received through multiple receiving elements of an ultrasound probe to obtain contrast-enhanced channel data corresponding to the time point;

calculating an image enhancement coefficient according to the contrast-enhanced channel data corresponding to the time point;

obtaining beam-formed data according to the contrast-enhanced channel data corresponding to the time point; and

adjusting the beam-formed data according to the image enhancement coefficient to obtain contrast-enhanced image data.

10. The method of claim 9 , wherein adjusting the beam-formed data according to the image enhancement coefficient comprises: multiplying the beam-formed data by the image enhancement coefficient.

11. The method of claim 9 , wherein the image enhancement coefficient is indicative of correlations among multiple pieces of the contrast-enhanced channel data corresponding to the multiple receiving elements of the ultrasound probe.

12. The method of claim 9 , wherein calculating the image enhancement coefficient corresponding to the time point according to the contrast-enhanced channel data corresponding to the time point comprises:

performing an envelope detection on each piece of the contrast-enhanced channel data corresponding to the time point to obtain envelope data, and calculating the correlation between each piece of the contrast-enhanced channel data corresponding to the time point according to the envelope data, wherein the envelope detection comprises an envelope detection at a power; or

calculating the correlation between each piece of the contrast-enhanced channel data corresponding to the time point directly using the contrast-enhanced channel data corresponding to the time point; or

performing a phase detection on each piece of the contrast-enhanced channel data corresponding to the time point to obtain phase data, and calculating the correlation between each piece of the contrast-enhanced channel data corresponding to the time point according to the phase data; or

performing a Fourier transform on each piece of the contrast-enhanced channel data corresponding to the time point to obtain frequency domain data, and calculating the correlation between each piece of the contrast-enhanced channel data corresponding to the time point according to the frequency domain data.

13. The method of claim 9 , wherein,

transmitting the ultrasound waves to the region of interest containing the contrast agents, receiving the echoes of the ultrasound waves to obtain the echo signals and extracting the contrast-enhanced channel data according to the echo signals comprises:

transmitting ultrasound waves in multiple angles to the region of interest containing the contrast agents;

receiving echoes of the ultrasound waves in the multiple angles to obtain echo signals corresponding to the multiple angles; and

extracting contrast-enhanced channel data corresponding to each angle of the multiple angles according to echo signals corresponding to the angle; and

calculating the image enhancement coefficient according to the contrast-enhanced channel data corresponding to the time point, obtaining the beam-formed data according to the contrast-enhanced channel data corresponding to the time point and adjusting the beam-formed data according to the image enhancement coefficient to obtain the contrast-enhanced image data at the time point comprises:

calculating image enhancement coefficient and beam-formed data corresponding to each angle of the multiple angles according to contrast-enhanced channel data corresponding to the angle; and

adjusting the beam-formed data corresponding to each angle according to the image enhancement coefficient corresponding to the angle to obtain a piece of adjusted data corresponding to the angle, and obtaining multiple pieces of the adjusted data corresponding to the multiple angles according to contrast-enhanced channel data corresponding to the multiple angles; and

the method further comprises performing coherent compound processing on the adjusted data corresponding to the multiple angles to obtain contrast-enhanced image data corresponding to the multiple angles by compounding the multiple pieces of the adjusted data corresponding to the multiple angles.

14. An image enhancement method for contrast enhanced ultrasound imaging, comprising:

transmitting ultrasound waves to a region of interest containing contrast agents;

receiving echoes of the ultrasound wave to obtain echo signals;

extracting contrast-enhanced channel data according to the echo signals, wherein multiple pieces of the contrast-enhanced channel data corresponding to one time point are received through multiple receiving elements of an ultrasound probe to obtain contrast-enhanced channel data corresponding to the time point;

calculating an image enhancement coefficient according to the contrast-enhanced channel data corresponding to the time point;

performing weighting processing on the calculated image enhancement coefficient and the contrast-enhanced channel data corresponding to the time point to obtain weighted channel data;

performing beam-forming on the weighted channel data to obtain beam-formed data; and

obtaining contrast-enhanced image data corresponding to the time point according to the beam-formed data.

15. The method of claim 14 , wherein the image enhancement coefficient is obtained by calculating correlations among the multiple pieces of the contrast-enhanced channel data corresponding to a same location point or the same one time point.

16. The method of claim 14 , wherein the contrast-enhanced channel data is obtained by one of:

performing time-delay processing on the echo signals, and extracting the contrast-enhanced channel data according to the processed echo signals; or

extracting the contrast-enhanced channel data, and performing time-delay processing on the extracted contrast-enhanced channel data.

17. The method of claim 14 , wherein,

transmitting the ultrasound waves to the region of interest containing the contrast agents, receiving the echoes of the ultrasound waves to obtain the echo signals and extracting the contrast-enhanced channel data according to the echo signals comprises:

transmitting ultrasound waves in multiple angles to the region of interest containing the contrast agents;

receiving echoes of the ultrasound waves in the multiple angles to obtain echo signals corresponding to the multiple angles; and

extracting contrast-enhanced channel data corresponding to each angle of the multiple angles according to echo signals corresponding to the angle to obtain contrast-enhanced channel data corresponding to the multiple angles;

calculating the image enhancement coefficient according to the contrast-enhanced channel data corresponding to the time point, performing the weighting processing on the calculated image enhancement coefficient and the contrast-enhanced channel data corresponding to the time point to obtain the weighted channel data and performing the beam-forming on the weighted channel data to obtain the beam-formed data comprises:

calculating image enhancement coefficient corresponding to each angle of the multiple angles according to contrast-enhanced channel data corresponding to the angle;

performing the weighting processing on the image enhancement coefficient corresponding to each angle and the contrast-enhanced channel data corresponding to the angle to obtain weighted channel data corresponding to the angle; and

performing the beam-forming on the weighted channel data to obtain a piece of beam-formed data corresponding to each angle to obtain multiple pieces of the beam-formed data corresponding to the multiple angles; and

obtaining the contrast-enhanced image data corresponding to the time point according to the beam-formed data comprises:

performing coherent compound processing on the beam-formed data corresponding to the multiple angles to obtain contrast-enhanced image data corresponding to the multiple angles by compounding the multiple pieces of the beam-formed data corresponding to the multiple angles.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Apr 15, 2026
From: BEIJING SHEN MINDRAY MEDICAL ELECTRONICS TECHNOLOGY ACADEMY CO., LTD.
To: BEIJING MINDRAY MEDICAL INSTRUMENT CO., LTD.
Reel/Frame 074378/0656 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 11, 2020
From: ZHANG, XIRUI; TANG, JIE; LUO, YUKUN; ZHANG, MINGBO; SANG, MAODONG; XIANG, LANXI; QIN, DONGHAI; FAN, WEI
To: BEIJING SHEN MINDRAY MEDICAL ELECTRONICS TECHNOLOGY RESEARCH INSTITUTE CO., LTD.; GENERAL HOSPITAL OF CHINESE PLA; SHENZHEN MINDRAY BIO-MEDICAL ELECTRONICS CO., LTD.
Reel/Frame 052621/0733 →
Continuity (2)
Continuation PCTCN2017106391 · Oct 16, 2017
Related Publication 20200253586A1 · Aug 13, 2020