Synthesis of 5-hydroxymethylfurfural
The present disclosure relates to a novel and improved synthesis of 5-hydroxymethylfurfural (HMF) from a glucose source. The synthesis of 5-hydroxymethylfurfural (HMF) is carried out by reacting a mixture comprising a Brønsted acid, a Lewis acid, water, dimethyl sulfoxide (DMSO), acetonitrile, and a glucose source.
1. A method of synthesizing 5-hydroxymethylfurfural (HMF) from a glucose source, wherein the method comprises reacting a mixture comprising a Brønsted acid, a Lewis acid, water, dimethyl sulfoxide (DMSO), acetonitrile, activated carbon, and a glucose source.
2. The method of claim 1 , wherein the method is carried out by providing a first mixture comprising the Brønsted acid, the Lewis acid, water, dimethyl sulfoxide (DMSO), acetonitrile; and then by adding the glucose source and said activated carbon to the first mixture.
3. The method of claim 1 , wherein the Brønsted acid comprises maleic acid.
4. The method of claim 1 , wherein the Lewis acid comprises AlCl 3 .
5. The method of claim 1 , wherein DMSO has a volume/volume percentage of 10-30%, acetonitrile has a volume/volume percentage of 30-50%, and the glucose source has a weight percentage of 20-40%.
6. The method of claim 1 , wherein the synthesizing of 5-hydroxymethylfurfural (HMF) is carried out at a temperature range of 150-250° C., and the synthesizing of 5-hydroxymethylfurfural (HMF) is substantially accomplished within 2-30 minutes.
7. The method of claim 1 , wherein the glucose source comprises glucose, cane sugar, cracked corn, milled corn, corn starch, corn mash, or any combination thereof.