Method for inhibiting osteoclast development
This invention provides a composition comprising Formula I, or salt thereof, wherein X is chlorine, Y is a methyl group, and R is an alkyl group having a carbon chain length of three carbon atoms. A method of inhibiting osteoclast development and a method for preventing bone erosion in a patient using the compositions of Formula I are disclosed.
1. A method of inhibiting osteoclast development comprising:
administering an effective amount of a haloanilide composition or a salt thereof to an osteoclast cell for inhibiting osteoclast development, wherein said haloanilide composition is not N-(3,4-dichlorophenyl)propanamide, and wherein said haloanilide is a composition of Formula I, or salt thereof, comprising
wherein X is chlorine, Y is a methyl group, and R is an alkyl group having a carbon chain length of three carbon atoms.
2. The method of claim 1 wherein said carbon atoms of said alkyl group are in either a straight chain or a branch chain arrangement.
3. The method of claim 2 wherein R is an isopropyl group.
4. A method for preventing bone erosion in a patient diagnosed with arthritis comprising:
administering to a patient an effective amount of a haloanilide composition or salt thereof for preventing bone erosion in a patient diagnosed with arthritis, wherein said haloanilide composition is not N-(3,4-dichlorophenyl)propanamide, and wherein said haloanilide is a composition of Formula I, or salt thereof, comprising
wherein X is chlorine, Y is a methyl group, and R is an alkyl group having a carbon chain length of three carbon atoms.
5. The method of claim 4 wherein said carbon atoms of said alkyl group are in either a straight chain or a branch chain arrangement.
6. The method of claim 5 wherein R is an isopropyl group.