IP Library › Granted Patent US 11,173,195
Granted Patent B2
US 11,173,195 · App. 16/889,838 · Granted Nov 16, 2021

Immunomodulatory pharmaceutical compositions including a synthetic peptide and transforming growth factor beta

Inventors: Robert Nussenblatt (Bethesda, MD); Baoying Liu (North Potomac, MD); Lai Wei (Rockville, MD); Elazar Rabbani (New York, NY); James J. Donegan (Amesbury, MA)
Assignee: Enzo Biochem, Inc.
A61K39/0008A61K35/17A61K2039/55583A61K2039/577
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Quick Facts
Patent No.
US 11,173,195
App. No.
16/889,838
Granted
Nov 16, 2021
Kind
B2
Abstract

The invention provides immunomodulatory pharmaceutical compositions that include a synthetic peptide and transforming growth factor beta, (TGF-β).

Claims (16)

1. A pharmaceutical composition, comprising

a synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2) or VTVDVTNNTEKTVKK (SEQ ID NO: 3); and

transforming growth factor beta (TGF-β).

2. The pharmaceutical composition, comprising:

the synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2).

3. The pharmaceutical composition, comprising:

the synthetic peptide which is VTVDVTNNTEKTVKK (SEQ ID NO: 3).

4. The pharmaceutical composition of claim 1 , consisting essentially of:

the synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2) or VTVDVTNNTEKTVKK (SEQ ID NO: 3); and

transforming growth factor beta (TGF-β).

5. The pharmaceutical composition of claim 4 , consisting essentially of:

the synthetic peptide which is GEPIPVTVDVTNNTEKTVKK (SEQ ID NO: 2); and

transforming growth factor beta (TGF-β).

6. The pharmaceutical composition of claim 4 , consisting essentially of:

the synthetic peptide which is VTVDVTNNTEKTVKK (SEQ ID NO: 3); and

transforming growth factor beta (TGF-β).

Assignments (3)
RELEASE OF SECURITY INTEREST Recorded Jul 24, 2023
From: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
To: ENZO BIOCHEM, INC.; ENZO CLINICAL LABS, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP; ENZO LIFE SCIENCES, INC.
Reel/Frame 064369/0031 →
SECURITY INTEREST Recorded Apr 3, 2023
From: ENZO LIFE SCIENCES, INC.; ENZO CLINICAL LABS, INC.; ENZO BIOCHEM, INC.; ENZO LIFE SCIENCES U.S. HOLDING CORP
To: GEMINO HEALTHCARE FINANCE, LLC D/B/A SLR HEALTHCARE ABL
Reel/Frame 063239/0103 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 16, 2020
From: RABBANI, ELAZAR; DONEGAN, JAMES J.; NUSSENBLATT, ROBERT; WEI, LAI; LIU, BAOYING
To: ENZO BIOCHEM, INC.
Reel/Frame 052945/0943 →
Continuity (6)
Continuation 16440007 · Jun 13, 2019
Division 15584108 · May 2, 2017
Continuation In Part 15189531 · Jun 22, 2016
Continuation 13871730 · Apr 26, 2013
Provisional Application 62342447 · May 27, 2016
Related Publication 20200368335A1 · Nov 26, 2020