IP Library Granted Patent US 11,253,725
Granted Patent B2
US 11,253,725 · App. 16/900,594 · Granted Feb 22, 2022

Time optimized radiation treatment

Inventors: Holger Goebel (Numbrecht, DE); Isabel Huth (Kuerten, DE)
A61N5/1031A61N5/103A61N5/107A61N5/1037A61N5/1039A61N5/1043A61N5/1049A61N5/1067A61N5/1071A61N5/1077A61N2005/1087
View Patent ↗
Loading inventors, assignments & file history…
Monitor This Case
Get email alerts when status or documents change.
Order Certified Copies
Most orders are placed with the USPTO same day — all within 24 business hours.
Order via The Patent Place →
Pre-filled with this patent's details
Quick Facts
Patent No.
US 11,253,725
App. No.
16/900,594
Granted
Feb 22, 2022
Kind
B2
Abstract

In one embodiment, a method includes receiving treatment information relating to a treatment plan for proton- or ion-beam therapy intended to irradiate a target tissue; receiving machine-limitation information relating to one or more limitations of one or more machines involved in the proton- or ion-beam therapy; determining a time-optimized beam current for a proton or ion beam based on the treatment information and the machine-limitation information, wherein the time-optimized beam current minimizes the time required to deliver a required quantity of monitor units to one of a plurality of spots, wherein each of the plurality of spots is a particular area of the target tissue; and delivering the time-optimized beam current to the particular area.

Claims (48)

1. A method performed by one or more devices, comprising:

receiving treatment information relating to a treatment plan for proton or ion-beam therapy intended to irradiate a target tissue;

receiving machine-parameter information relating to one or more parameters of one or more machines involved in the proton or ion-beam therapy;

determining a beam current for a proton or ion beam based on the treatment information and the machine-parameter information, wherein the beam current is determined by considering a spot exposure time required to deliver a certain quantity of monitor units to one or more of a plurality of spots, wherein at least one of the plurality of spots is a particular area of the target tissue; and

generating a control signal to cause a treatment machine to provide the proton or ion beam after the beam current is determined;

wherein the machine-parameter information comprises information related to: a machine parameter of a dose-monitor system, a machine parameter of a beam-position and beam-shape monitoring system, a maximum beam current, or a machine parameter of a particle-accelerator.

2. The method of claim 1 , wherein the treatment plan specifies one or more of:

a target volume of the target tissue;

a prescribed beam position in x- and y-coordinates per spot at an isocenter, wherein the x- and y-coordinates are transversal to a beam direction, a prescribed energy of the proton or ion beam per spot, and a prescribed amount of monitor units per spot;

a set of field parameters that specify a direction from which the proton or ion beam is to be shot, a position of the target volume, and treatment specific parameters for one or more fields; or

a fraction parameter that specifies a portion of treatment dose that is to be delivered for a given treatment session.

3. The method of claim 1 , wherein the machine parameter of the dose-monitor system is a beam parameter that the dose-monitor system is configured to monitor.

4. The method of claim 1 , wherein the machine parameter of the beam-position and beam-shape monitoring system is a beam parameter that the beam-position and beam-shape monitoring system is configured to monitor.

5. The method of claim 1 , wherein the determining of the beam current comprises:

determining a value of prescribed monitor units;

determining a time of exposure required to deliver the prescribed monitor units;

calculating a ratio based on the value of the prescribed monitor units and the determined time of exposure; and

if the ratio meets a certain criterion, setting the beam current to a certain beam current level for the dose-monitor system or the beam-position and beam shape-monitoring system.

6. The method of claim 1 , further comprising determining a spot duration based on the beam current.

7. The method of claim 6 , wherein the spot duration is for at least one of the spots.

8. The method of claim 1 , wherein the determining of the beam current comprises:

determining a time of exposure required to deliver a certain treatment dose;

calculating a ratio based on a prescribed amount of monitor units and the determined time of exposure; and

if the ratio meets a criterion, setting the beam current to a certain beam current level for the dose-monitor system or the beam-position and beam shape-monitoring system.

9. The method of claim 1 , wherein the spots are defined in the treatment plan.

10. The method of claim 1 , wherein the particular area is an energy layer for the target tissue, wherein the energy layer is defined by one or more z-locations of a target volume prescribed in the treatment plan.

11. The method of claim 1 , further comprising:

monitoring the proton or ion beam, and an amount of monitor units delivered to the target tissue; and

adjusting a position of the proton or ion beam, an intensity of the proton or ion beam, a depth of the proton beam, or a combination of the foregoing.

12. The method of claim 1 , wherein the target tissue is diseased tissue.

13. The method of claim 1 , wherein the treatment machine comprises a cyclotron or a synchrotron.

14. The method of claim 1 , wherein the proton or ion beam is for delivery to the particular area of the target tissue.

15. A system comprising:

one or more processors; and

one or more computer-readable non-transitory storage media coupled to the one or more of the processors, the one or more computer-readable non-transitory storage media comprising instructions, which when executed by the one or more processors, will cause the system to:

receive treatment information relating to a treatment plan for proton or ion-beam therapy intended to irradiate a target tissue;

receive machine-parameter information relating to one or more parameters of one or more machines involved in the proton or ion-beam therapy;

determine a beam current for a proton or ion beam based on the treatment information and the machine-parameter information, wherein the beam current is determined by considering a spot exposure time required to deliver a certain quantity of monitor units to one or more of a plurality of spots, wherein at least one of the plurality of spots is a particular area of the target tissue; and

generating a control signal to cause a treatment machine to provide the proton or ion beam after the beam current is determined;

wherein the machine-parameter information comprises information related to: a machine parameter of a dose-monitor system, a machine parameter of a beam-position and beam-shape monitoring system, a maximum beam current, or a machine parameter of a particle-accelerator.

16. One or more computer-readable non-transitory storage media comprising one or more instructions, which when executed by one or more devices, will cause a method to be performed, the method comprising:

receiving treatment information relating to a treatment plan for proton or ion-beam therapy intended to irradiate a target tissue;

receiving machine-parameter information relating to one or more parameters of one or more machines involved in the proton or ion-beam therapy;

determining a beam current for a proton or ion beam based on the treatment information and the machine-parameter information, wherein the beam current is determined by considering a spot exposure time required to deliver a certain quantity of monitor units to one or more of a plurality of spots, wherein at least one of the plurality of spots is a particular area of the target tissue; and

generating a control signal to cause a treatment machine to provide the proton or ion beam after the beam current is determined;

wherein the machine-parameter information comprises information related to: a machine parameter of a dose-monitor system, a machine parameter of a beam-position and beam-shape monitoring system, a maximum beam current, or a machine parameter of a particle-accelerator.

17. The system of claim 15 , wherein the machine parameter of the dose-monitor system is a beam parameter that the dose-monitor system is configured to monitor.

18. The system of claim 15 , wherein the machine parameter of the beam-position and beam-shape monitoring system is a beam parameter that the beam-position and beam-shape monitoring system is configured to monitor.

Assignments (2)
CHANGE OF NAME Recorded Feb 9, 2021
From: VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH
To: VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH & CO. KG
Reel/Frame 055265/0930 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 12, 2020
From: GOEBEL, HOLGER, DR; HUTH, ISABEL
To: VARIAN MEDICAL SYSTEM PARTICLE THERAPY GMBH
Reel/Frame 052932/0960 →
Continuity (3)
Continuation 16091515
Provisional Application 62318692 · Apr 5, 2016
Related Publication 20200298020A1 · Sep 24, 2020