IP Library Granted Patent US 10,987,511
Granted Patent B2
US 10,987,511 · App. 16/906,154 · Granted Apr 27, 2021

Stimulation systems and related user interfaces

Inventors: Matthew J. Gani (Seattle, WA); Kaitlin Taylor (Exton, PA); Viral S. Thakkar (Chester Springs, PA); Douglas G. Evans (Downingtown, PA)
Assignee: Lungpacer Medical Inc.
A61N1/05A61M25/00A61N1/3601G06F9/542
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Quick Facts
Patent No.
US 10,987,511
App. No.
16/906,154
Granted
Apr 27, 2021
Kind
B2
Abstract

A system for stimulating body tissue may include a user interface and a control unit. The control unit may include a processor and non-transitory computer readable medium. The non-transitory computer readable medium may store instructions that, when executed by the processor, causes the processor to identify an electrode combination and determine a threshold charge for use in stimulating the body tissue. The processors identifications and determinations may be based at least partially on input received via the user interface.

Claims (64)

1. A system for stimulating body tissue, the system comprising:

a user interface; and

a control unit including a processor and a non-transitory computer readable medium storing instructions that, when executed by the processor, causes the processor to identify an electrode combination and determine a threshold charge for use in stimulating the body tissue, based at least partially on input received via the user interface.

2. The system of claim 1 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when identifying the electrode combination, to:

select a set of electrode combinations from a domain of electrode combinations;

stimulate from all selected electrode combinations; and

receive input on whether a requisite stimulation was detected for each stimulation.

3. The system of claim 2 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when identifying the electrode combination, to:

individually select an electrode combination from the set of electrode combinations which provided the requisite stimulation;

stimulate from the individually selected electrode combination; and

for each stimulation, receive input on whether the requisite stimulation was detected.

4. The system of claim 3 , wherein receiving input on whether the requisite stimulation was detected includes prompting a user to provide feedback via the user interface on whether the requisite stimulation was detected.

5. The system of claim 1 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when determining a threshold charge, to determine a coarse threshold charge and a fine threshold charge.

6. The system of claim 5 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when determining a coarse threshold charge to:

perform an electrode sweep at a first charge;

receive input on whether a requisite stimulation was detected; and

if the requisite stimulation was detected, set the coarse threshold charge at a charge of the most recent electrode sweep; or

if the requisite stimulation was not detected, perform an electrode sweep at a second charge greater than the first charge.

7. The system of claim 5 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when determining a fine threshold charge to:

select a charge level that corresponds to a determined coarse threshold;

determine a domain of charges based on the determined coarse threshold;

deliver stimulation at the charge level corresponding to the determined coarse threshold; and

receive input on whether the requisite stimulation was detected.

8. The system of claim 1 , further comprising one or more stimulation arrays supported on an intravenous catheter, and the body tissue is a muscle that activates a lung or a nerve that innervates a muscle that activates a lung.

9. The system of claim 1 , wherein the user interface includes an anatomical indication window, one or more phase buttons, and one or more stimulation level indication windows.

10. A system for stimulating body tissue, the system comprising:

one or more sensors configured to be affixed to, or inserted in, a body to measure one or more physiological parameters of the body;

a stimulation array;

a user interface; and

a control unit including a processor and a non-transitory computer readable medium storing instructions that, when executed by the processor, causes the processor to assess a position of the stimulation array, determine an electrode combination of the stimulation array for use in stimulating the body tissue, and determine a threshold charge for use in stimulating the body tissue.

11. The system of claim 10 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when identifying the electrode combination, to:

select a set of electrode combinations from a domain of electrode combinations;

stimulate from all selected electrode combinations;

receive input on whether requisite stimulation was detected during stimulation from all selected electrode combinations;

individually select an electrode combination from the set of electrode combinations which provided requisite stimulation;

stimulate from the individually selected electrode combination; and

receive input on whether requisite stimulation was detected during stimulation from the individually selected electrode combination.

12. The system of claim 10 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when determining a threshold charge, to:

perform an electrode sweep at a first charge;

receive input on whether requisite stimulation was detected; and

if requisite stimulation was detected, set the coarse threshold charge at the charge of the most recent electrode sweep; or

if requisite stimulation was not detected; perform an electrode sweep at a second charge;

wherein the second charge is greater than the first charge.

13. The system of claim 10 , wherein the one or more sensors include one or more sensors configured to detect: airway pressure, airway flowrate, blood gas levels, heart rate, breathing rate, tidal volume, transpulmonary pressure, impedance, lung gas distribution, electromyographic activity, transdiaphragmatic pressure, or a combination thereof.

14. The system of claim 10 , wherein the instructions stored in the non-transitory computer readable medium further cause the processor to:

assist a user in determining if the one or more stimulation arrays are correctly placed, relative to a patient; or

schedule a number of stimulations within a set time interval.

15. The system of claim 10 , wherein:

the stimulation array includes at least two groups of electrodes;

identifying an electrode combination includes identifying an electrode combination for each group of electrodes; and

identifying a threshold charge includes identifying a threshold charge for each group of electrodes.

16. The system of claim 10 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when prompted by a user, to terminate the delivery of stimulation energy.

17. The system of claim 10 , wherein the instructions stored in the non-transitory computer readable medium further cause the processor to determine whether a stimulation would exceed a maximum allowable charge.

18. A system for stimulating body tissue, the system comprising:

a catheter including a plurality of electrodes; and

a user interface; and

a control unit including a processor and a non-transitory computer readable medium storing instructions that, when executed by the processor, causes the processor to, based on input received via the user interface:

determine a coarse threshold suitable for stimulating the body tissue, wherein the body tissue is a phrenic nerve that innervates a diaphragm;

identify an electrode combination from the plurality of electrodes, wherein the electrode combination is used to deliver stimulation to the phrenic nerve; and

determine a fine threshold suitable for stimulating the body tissue via the identified electrode combination.

19. The system of claim 17 , wherein the instructions stored in the non-transitory computer readable medium cause the processor to determine whether the catheter is placed in a position, relative to a body, suitable for delivering stimulation to the body tissue.

20. The system of claim 17 , wherein the instructions stored in the non-transitory computer readable medium cause the processor, when prompted by a user, to schedule a number of stimulations within a set time interval, wherein:

each stimulation of the number of stimulations is delivered via the identified electrode combination; and

the number of stimulations and the duration of the time interval are parameters adjustable via the user interface.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 22, 2020
From: GANI, MATTHEW J.; TAYLOR, KAITLIN; THAKKAR, VIRAL S.; EVANS, DOUGLAS G.
To: LUNGPACER MEDICAL INC.
Reel/Frame 052996/0727 →
Continuity (3)
Continuation 16677794 · Nov 8, 2019
Provisional Application 62757576 · Nov 8, 2018
Related Publication 20200316368A1 · Oct 8, 2020
Cited By (1)
US 12,673,200