Method for the treatment of pancreatitis
A composition for preventing and/or treating pancreatitis and a method of prevention and/or treatment of pancreatitis are disclosed. The composition include an aryl ethene compound, a pharmaceutically acceptable salt thereof, or a solvate thereof, as an active ingredient. The method includes administering the aryl ethene compound, an isomer, a pharmaceutically acceptable salt thereof, or a solvate thereof, in an effective amount to a subject in need thereof.
1. A method for treating and/or preventing pancreatitis in a subject in need thereof, comprising administering to the subject an effective amount of a compound,
wherein the compound is selected from the following compounds:
or an isomer, a pharmaceutically acceptable salt thereof, or a solvate thereof.
2. The method of claim 1 , wherein the pancreatitis is acute pancreatitis.
3. The method of claim 1 , wherein the subject is a mammal.
4. The method of claim 3 , wherein the mammal is human.
5. The method of claim 1 , wherein the compound is (E)-5-(4-hydroxyphenyl)-5-(4-(4-isopropylpiperazin-1-yl)phenyl)-4-phenylpent-4-en-1-ol of the following chemical formula:
or an isomer, a pharmaceutically acceptable salt, or a solvate thereof.
6. A method for preventing and/or treating pancreatitis in a subject in need thereof, comprising administering an effective amount of (E)-5-(4-hydroxyphenyl)-5-(4-(4-isopropylpiperazin-1-yl)phenyl)-4-phenylpent-4-en-1-ol of the following chemical formula:
or a therapeutically acceptable salt thereof
to the subject.
7. The method of claim 6 , wherein the pancreatitis is acute pancreatitis.