IP Library Granted Patent US 11,475,579
Granted Patent B2
US 11,475,579 · App. 16/908,422 · Granted Oct 18, 2022

Image registration of treatment planning image, intrafraction 3D image, and intrafraction 2D x-ray image

Inventors: Petr Jordan (Redwood City, CA); Calvin R. Maurer, Jr. (San Jose, CA); Andriy Myronenko (San Mateo, CA); Jonathan Cecil Chappelow (Campbell, CA)
Assignee: Accuray Incorporated
G06T7/337A61B6/032A61B6/4258A61B6/5223A61B6/5235A61B6/5264A61N5/1049G06T7/0014G06T7/20G06T7/248G06T7/30G06T15/08G06T15/205A61N5/103A61N2005/1062G06T2207/10072G06T2207/10124G06T2207/30004G06T2210/41
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Quick Facts
Patent No.
US 11,475,579
App. No.
16/908,422
Granted
Oct 18, 2022
Kind
B2
Abstract

A method of the present disclosure includes performing, by a processing device, a first image registration between a reference image of a patient and a motion image of the patient to perform alignment between the reference image and the motion image, wherein the reference image and the motion image include a target position of the patient. The method further includes performing, by the processing device, a second image registration between the reference image and a motion x-ray image of the patient, via a first digitally reconstructed radiograph (DRR) for the reference image of the patient. The method further includes tracking at least a translational change in the target position based on the first registration and the second registration.

Claims (31)

1. A method, comprising:

performing, by a processing device, a first image registration between a reference image of a patient and a motion image of the patient to perform alignment between the reference image and the motion image, wherein the reference image and the motion image include a target position of the patient;

performing, by the processing device, a second image registration between the reference image and a motion x-ray image of the patient; and

tracking at least a translational change in the target position based on the first registration and the second registration.

2. The method of claim 1 , wherein the reference image and the motion image are three-dimensional (3D) images.

3. The method of claim 2 , wherein the reference image is a 3D planning image.

4. The method of claim 2 , wherein the reference image is one of: a kilovoltage computed tomography (kV-CT) image, a magnetic resonance imaging (MRI) image, a kilovoltage cone beam computed tomography (kV-CBCT) image, or a megavoltage computed tomography (MVCT) image.

5. The method of claim 2 , wherein the motion image is one of: a kilovoltage cone beam computed tomography (kV-CBCT) image, a megavoltage cone beam computed tomography (MV-CBCT) image, a megavoltage computed tomography (MVCT) image, or a helical kV-CT image.

6. The method of claim 1 , wherein the first image registration is used to perform a global rotational patient alignment, and wherein the second image registration is used to maintain the global rotational patient alignment.

7. The method of claim 1 , wherein the reference image, the motion image, and the motion x-ray image are generated by an imaging source of a helical radiation delivery system or by one or more imaging sources at different positions with respect to the patient.

8. The method of claim 1 , further comprising:

detecting a fiducial migration associated with the patient based on the reference image; and

modifying a tracking algorithm associated with a treatment delivery of the patient to account for the fiducial migration.

9. A non-transitory computer readable medium comprising instructions that, when executed by a processing device, cause the processing device to:

perform, by a processing device, a first image registration between a reference image of a patient and a motion image of the patient to perform alignment between the reference image and the motion image, wherein the reference image and the motion image include a target position of the patient;

perform, by the processing device, a second image registration between the reference image and a motion x-ray image of the patient; and

track at least a translational change in the target position based on the first registration and the second registration.

10. The non-transitory computer readable medium of claim 9 , wherein the reference image, the motion image, and the motion x-ray image are generated by an imaging source of a helical radiation delivery system or by one or more imaging sources at different positions with respect to the patient.

11. The non-transitory computer readable medium of claim 9 , the processing device further to:

detect a fiducial migration associated with the patient based on the first image registration; and

modify a tracking algorithm associated with a treatment delivery of the patient to account for the fiducial migration.

12. A method, comprising:

performing, by a processing device, a first image registration between a reference image of a patient and a motion image of the patient, to perform alignment between the reference image and the motion image, wherein the reference image and the motion image include a target position of the patient;

performing, by the processing device, a second image registration between the motion image and a motion x-ray image of the patient; and

tracking at least one of a translational change, a rotation change, and a deformation change in the target position based on the first registration and the second registration.

13. The method of claim 12 , wherein the motion image has a higher spatial resolution than the reference image.

14. The method of claim 12 , wherein the reference image is one of: a kilovoltage computed tomography (kV-CT) image, a magnetic resonance imaging (MRI) image, a kilovoltage cone beam computed tomography (kV-CBCT) image, or a megavoltage computed tomography (MVCT) image.

15. The method of claim 12 , wherein the motion image is one of: a kilovoltage cone beam computed tomography (kV-CBCT) image, a megavoltage cone beam computed tomography (MV-CBCT) image, a megavoltage computed tomography (MVCT) image, or a helical kV-CT image.

16. The method of claim 12 , further comprising:

detecting a fiducial migration associated with the patient; and

modifying a tracking algorithm associated with a treatment delivery of the patient to account for the fiducial migration.

Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 13, 2025
From: ACCURAY INCORPORATED
To: ACCURAY LLC
Reel/Frame 072421/0584 →
RELEASE OF SECURITY INTEREST Recorded Jun 6, 2025
From: FIRST-CITIZENS BANK & TRUST COMPANY
To: ACCURAY INCORPORATED
Reel/Frame 071638/0034 →
SECURITY INTEREST Recorded May 14, 2021
From: ACCURAY INCORPORATED; TOMOTHERAPY INCORPORATED
To: SILICON VALLEY BANK, AS ADMINISTRATIVE AND COLLATERAL AGENT
Reel/Frame 056247/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jun 23, 2020
From: JORDAN, PETR; MAURER, CALVIN R., JR.; MYRONENKO, ANDRIY; CHAPPELOW, JONATHAN CECIL
To: ACCURAY INCORPORATED
Reel/Frame 053012/0393 →
Continuity (3)
Continuation 15862438 · Jan 4, 2018
Provisional Application 62443581 · Jan 6, 2017
Related Publication 20200320722A1 · Oct 8, 2020