Granted Patent
B2
US 12,295,845 · App. 16/918,295 · Granted May 13, 2025
Device, system, and method for transcatheter treatment of valvular regurgitation
Inventors:
Alexander K. Khairkhahan (Palo Alto, CA); Janine C. Robinson (Half Moon Bay, CA); Alan R. Klenk (San Jose, CA); Anuja Patel (Palo Alto, CA); Zaya Tun (Livermore, CA); Robert Quintos (Palo Alto, CA); Brett Snyder (Campbell, CA)
Assignee:
Polares Medical Inc.
A61F2/246A61F2/2466A61F2210/0014A61F2220/0016A61F2220/0075A61F2230/0006A61F2230/0091A61F2250/0018A61F2250/0098
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Abstract
The invention relates to a device for use in the transcatheter treatment of mitral valve regurgitation, specifically a coaptation assistance element for implantation across the valve; a system including the coaptation assistance element and anchors for implantation; a system including the coaptation assistance element and delivery catheter; and a method for transcatheter implantation of a coaptation element across a heart valve.
Claims (29)
1. A coaptation assistance element for treating mal-coaptation of a heart valve, the heart valve having an annulus, the coaptation assistance element comprising:
a first surface and an opposed second surface, each surface bounded by a first lateral edge, a second lateral edge, an inferior edge, and a superior edge;
a hub configured to receive a primary anchor; and
a plurality of struts spaced around the hub and extending outward from the hub, the plurality of struts comprising at least a first strut configured to be implanted within a heart and a second strut configured to be implanted within the heart,
wherein the coaptation assistance element comprises a layer positioned outward from the hub configured to be an reinforcement layer for one or more secondary anchors, and
one or more anchor tethers extending through the coaptation assistance element. the one or more anchor tethers configured to guide the one or more secondary anchors toward the coaptation assistance element.
2. The coaptation assistance element of claim 1 , wherein the layer comprises ePTFE.
3. The coaptation assistance element of claim 1 , wherein the layer comprises two or more separate anchor zones.
4. The coaptation assistance element of claim 3 , where the two or more separate anchor zones are diametrically opposed.
5. The coaptation assistance element of claim 1 , further comprising the one or more secondary anchors, wherein the one or more secondary anchors are helical anchors.
6. The coaptation assistance element of claim 5 , wherein the one or more secondary anchors comprise a sharpened tip configured to penetrate the layer.
7. The coaptation assistance element of claim 1 , further comprising one or more anchor guide rail configured to extend over the one or more anchor tethers.
8. A coaptation assistance element for treating mal-coaptation of a heart valve, the heart valve having an annulus, the coaptation assistance element comprising:
a first surface and an opposed second surface, each surface bounded by a first lateral edge, a second lateral edge, an inferior edge, and a superior edge, wherein the first surface comprises a first coaptation surface configured for the anterior leaflet to coapt against;
a hub;
a plurality of struts spaced around the hub and extending outward from the hub, the plurality of struts comprising at least a first strut configured to be implanted within a heart and a second strut configured to be implanted within the heart,
wherein the first coaptation surface comprises a layer positioned outward from the hub configured to be an reinforcement layer for the first coaptation surface, wherein the layer extends only along a portion of the second strut.
9. The coaptation assistance element of claim 8 , wherein the layer is disposed on the anterior side of the second strut.
10. The coaptation assistance element of claim 8 , wherein the layer is disposed on the posterior side of the second strut.
11. The coaptation assistance element of claim 8 , wherein the layer comprises a mesh.
12. The coaptation assistance element of claim 8 , wherein the layer comprises UHMPE.
13. The coaptation assistance element of claim 8 , wherein the hub and the plurality of struts are integrally formed.
14. The coaptation assistance element of claim 1 , further comprising the primary anchor, wherein the primary anchor comprises a helical anchor.
15. The coaptation assistance element of claim 1 , wherein the one or more anchor tethers are configured to extend around a release wire.
16. The coaptation assistance element of claim 1 , wherein the one or more secondary anchors comprise a smaller diameter than the primary anchor.
17. The coaptation assistance element of claim 1 , wherein the one or more secondary anchors comprise a smaller pitch than the primary anchor.
18. The coaptation assistance element of claim 8 , wherein the layer extends only along a ventricular portion of the coaptation assistance element.
19. The coaptation assistance element of claim 8 , wherein the second strut comprises a total length greater than the first strut.
20. The coaptation assistance element of claim 8 , wherein the second strut extends to or toward the inferior edge.
Assignments (2)
CHANGE OF NAME
Recorded Nov 29, 2021
From: MIDDLE PEAK MEDICAL INC.
To: POLARES MEDICAL INC.
Reel/Frame 058264/0345 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Sep 10, 2020
From: KHAIRKHAHAN, ALEXANDER K.; ROBINSON, JANINE C.; KLENK, ALAN R.; PATEL, ANUJA; TUN, ZAYA; QUINTOS, ROBERT; SNYDER, BRETT
To: MIDDLE PEAK MEDICAL, INC.
Reel/Frame 053739/0630 →
Continuity (4)
Provisional Application
62470684
· Mar 13, 2017
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