Medication risk mitigation system and method

1. A method for generating a report for medication risk mitigation (MRM), the method comprising:

A network linked computer program product comprising a non-transitory computer readable medium having program instructions stored in a memory device, the instructions executable by a processor to direct the performance of operations for the management of a regimen for a patient's use of prescribed medication, the program instructions comprising the steps of:

initializing a prospective intervention comprising the steps of:

receiving at least one medication input from a prescriber for the patient into the memory device;

comparing the at least one medication input for the patient to at least one intrinsic component data source and/or extrinsic component data source,

wherein the at least one intrinsic component data source and/or extrinsic component data source includes one or more weighted risk factors;

selecting another medication when the at least one medication input is linked with a contraindication based on the at least one intrinsic component data source and/or extrinsic component data source, including the weighted risk factors;

sending a first message including the another medication to the prescriber through the network linked computer program if the at least one medication input is matched with at least one contraindication based on the comparison between the at least one medication input and the at least one intrinsic component data source and/or extrinsic component data source;

editing the at least one medication input with any modifications the prescriber may make based on the contraindication, thereby creating one or more prescribed medications;

initializing a concurrent intervention comprising the steps of:

sending a second message to a pharmacist device through the network linked computer program comprising the one or more prescribed medications;

comparing, at the pharmacist device, the one or more prescribed medications for the patient to the at least one intrinsic component data source and/or extrinsic component data source;

selecting another medication when the prescribed medication is linked with a contraindication based on the at least one intrinsic component data source and/or extrinsic component data source, including the weighted risk factors;

sending, at the pharmacist device, a third message including the another medication to the prescriber through the network linked computer program if at least one of the one or more prescribed medications is matched with at least one contraindication based on the comparison between the one or more prescribed medications and the at least one intrinsic component data source and/or extrinsic component data source;

editing the one or more prescribed medications with any modifications the prescriber may make based on the contraindication, thereby creating one or more revised prescribed medications;

initializing a retrospective intervention comprising the steps of:

recognizing a triggering event;

comparing the one or more prescribed medications and/or revised prescribed medications for a patient to the at least one intrinsic component data source and/or extrinsic component data source;

selecting another medication when the prescribed medication is linked with a contraindication based on the at least one intrinsic component data source and/or extrinsic component data source, including the weighted risk factors;

sending a fourth message including the another medication though the networked linked computer program to the prescriber if at least one of the one or more prescribed medications or revised prescribed medications is matched with at least one contraindication based on the comparison between the one or more prescribed medications or revised prescribed medications and the at least one intrinsic component data source and/or extrinsic component data source; and

editing the one or more prescribed medications or revised prescribed medications with any modifications the prescriber may make based on the contraindication, thereby creating one or more revised prescribed medications;

generating an output MRM report comprising a visualized representation of weighted risk profiles, weighted risk factors, and a list of options for medication dosage modification, medication substitution and/or medication cessation; and

the pharmacist dispensing the one or more prescribed medications after the concurrent intervention and/or the retrospective intervention,

wherein the weighted risk factors include:

Food and Drug Administration (FDA) adverse event reporting data,

Anticholinergic Cognitive Burden (ACB),

sedative burden for a particular drug,

drug metabolism pathway,

drug-drug interactions,

drug-gene interactions,

wherein the weighted risk profiles include:

each of the aggregated weighted risk factors,

the number of medications being taken concurrently,

duration of therapy of the existing medications,

Anticholinergic Cognitive Burden Index

Creatine Clearance,

interaction warnings;

wherein the intrinsic component data source comprises:

lab test results for an individual patient;

concomitant medications prescribed to an individual patient;

documented medication allergies for a particular patient;

pharmacogenomics data for a particular medication(s) based on medication metabolizing isoenzymes and transporters and their impact; and

medication adherence information for an individual patient; and

wherein the extrinsic component data source comprises:

Beers listed medications;

medication name;

START/STOPP criteria;

FDA adverse event reporting data;

Drug metabolism data;

Extent of drug metabolism pathways data;

black-box Food and Drug Administration warnings;

central nervous system (CNS) sedative burdens; and

aggregated Anticholinergic Burden.

2. The method of claim 1 , wherein the intrinsic component data source and/or the extrinsic component data source are updated dynamically as new information becomes available.

3. The method claim 2 , wherein the triggering event occurs when the intrinsic component data source and/or the extrinsic component data source are updated.

4. The method claim 1 , wherein the triggering event occurs: (i) every six months after the prospective intervention, (ii) after the patient falls, and/or (iii) after the patient's hospitalization.