IP Library › Granted Patent US 11,160,829
Granted Patent B2
US 11,160,829 · App. 16/932,075 · Granted Nov 2, 2021

Synthesis and antimicrobial uses of dinuclear silver(I) pyrazolates

Inventors: Raphael G. Raptis (Miami, FL); Indranil Chakraborty (Miami, FL); Shambhu Kandel (Miami, FL)
Assignee: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
A61K33/38A61P31/04C07F1/005C07F9/65848
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Quick Facts
Patent No.
US 11,160,829
App. No.
16/932,075
Granted
Nov 2, 2021
Kind
B2
Abstract

Novel dinuclear silver(I) pyrazolido complexes and methods of synthesizing them are provided. Advantageously, the novel silver(I) pyrazolido complexes have excellent antimicrobial activity and methods of using said complexes to treat bacterial, fungal, and viral infections are also provided.

Claims (4)

1. A water soluble dinuclear silver (I) pyrazolido complex having the following structure

or a pharmaceutically acceptable salt thereof.

2. A composition comprising the dinuclear silver (I) pyrazolido complex according to claim 1 .

3. The composition according to claim 2 , further comprising one or more ingredients selected from anti-bacterial agents, anti-viral agents, fungicidal agents, anesthetic agents, buffers, and pharmacological excipients.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 12, 2020
From: RAPTIS, RAPHAEL G.; CHAKRABORTY, INDRANIL; KANDEL, SHAMBHU
To: THE FLORIDA INTERNATIONAL UNIVERSITY BOARD OF TRUSTEES
Reel/Frame 053476/0815 →
Continuity (3)
Continuation 16456834 · Jun 28, 2019
Provisional Application 62722664 · Aug 24, 2018
Related Publication 20200376025A1 · Dec 3, 2020