Composition comprising poly I:C and LAG-3-IGG fusion protein
The present invention provides a medicine containing a Toll-like receptor agonist, LAG-3 protein, a variant or derivative thereof.
1. A pharmaceutical composition comprising
Poly I:C or a salt thereof and
a fusion protein of lymphocyte activation gene 3 (LAG-3) protein and IgG.
2. The pharmaceutical composition according to claim 1 , consisting of
a preparation comprising Poly I:C or a salt thereof and
a preparation comprising a fusion protein of LAG-3 protein and IgG,
wherein the two preparations are formulated for combined administration.
3. The pharmaceutical composition according to claim 1 , further comprising at least one cancer-antigen derived peptide.
4. The pharmaceutical composition according to claim 3 , consisting of
a preparation comprising Poly I:C or a salt thereof,
a preparation comprising a fusion protein of LAG-3 protein and IgG, and
a preparation comprising at least one type of cancer-antigen derived peptide
wherein the three preparations are formulated for combined administration.
5. The pharmaceutical composition according to claim 3 , comprising two or more cancer-antigen derived peptides.