ENT guidewire

1. Apparatus, comprising:

a guidewire, comprising a flexible biocompatible tube having a tube distal end configured to be inserted into an orifice of a body of a living subject;

a camera fixed in proximity to the tube distal end;

a pair of biocompatible electrodes, formed on an outer surface of the flexible biocompatible tube at the tube distal end, configured to contact tissue of the body; and

a processor, configured:

to inject a signal via the electrodes, so as to electrically stimulate the contacted tissue; and in response to the stimulation, to provide an indication if the tissue is fibrotic, wherein the indication is provided in response to visible motion of the contacted tissue occurring detected based on images captured by the camera.

2. An apparatus according to claim 1 , comprising:

a planar resilient strip inserted into the internal lumen, the strip having a strip proximal end and a strip distal end fixed to the tube distal end;

a coil spring fixed to the strip proximal end so that an axis of symmetry of the coil is coplanar with the strip, the coil spring containing a coil lumen;

a wire, threaded through the coil lumen and having a termination fixed to the strip distal end, so that pulling on the wire causes the strip and the tube to bend.

3. The apparatus according to claim 2 , wherein the strip has a rectangular cross-section, and comprises super-elastic material.

4. The apparatus according to claim 2 , wherein the coil spring comprises a tension spring having coils contacting each other when the spring is unloaded.

5. The apparatus according to claim 2 , wherein the strip has a first surface and a second surface opposite the first surface, and wherein the wire is threaded between the first surface and the coil spring and is fixed to the first surface at the strip distal end, so that pulling on the wire causes the strip and the tube to bend in a bending direction defined by a vector from the second surface to the first surface.

6. The apparatus according to claim 5 , and comprising a further wire threaded between the second surface and the coil spring and fixed to the second surface at the strip distal end, so that pulling on the further wire causes the strip and the tube to bend in a further direction opposite the direction defined by the vector.

7. The apparatus of claim 2 , wherein the strip distal end is formed with a plurality of holes and wherein the camera is configured to be fixed to the strip distal end based on introducing glue through the holes.

8. The apparatus of claim 1 , comprising:

a first and a second fiber optic having distal ends located in proximity to the tube distal end, and configured to provide illumination into the body; and

a processor, comprising an optics module, coupled to at least one of the first and the second fiber optics, configured to generate the illumination as photo-exciting illumination.

9. The apparatus according to claim 8 , wherein the optics module is configured to record returning excited photoluminescent illumination produced in response to the photo-exciting illumination.

10. The apparatus according to claim 9 , wherein the first fiber optic is coupled so as to radiate the photo-exciting illumination, and the second fiber optic is coupled to receive the returning excited photoluminescent illumination after filtration of the photo-exciting illumination.

11. The apparatus according to claim 1 , wherein the injected signal comprises an applied predetermined voltage and wherein the module is configured to measure an impedance of the contacted tissue in response to a current generated by the voltage so as to provide an indication if the tissue is fibrotic.

12. The apparatus according to claim 1 , wherein the injected signal comprises pulses applied at a frequency greater than a heart rate of the living subject, so as to electrically stimulate the contacted tissue, and so as to provide an indication if the tissue is fibrotic.

13. The apparatus of claim 1 , comprising:

a magnetic sensor fixed to the tube distal end and in communication with a magnetic tracking system;

wherein the magnetic sensor is configured to track the position and orientation of the camera; and

a processor configured:

to track a position and orientation of the camera within the body based on output from the magnetic sensor,

to acquire two-dimensional image of internal elements of the body with the tracked camera,

in response to the tracked position and orientation of the camera, to overlay the two-dimensional image of the internal elements on three-dimensional voxels of a computerized tomographic (CT) image of the internal elements so as to form a combined image, and

to present a combined image on a screen.

14. The apparatus according to claim 13 , wherein combining the image comprises overlaying the camera image onto the CT image using projective texture mapping.

15. The apparatus according to claim 13 , wherein combining the image comprises incorporating three-dimensional information derived from pixels of the CT image into the camera image.