System and method for making cannabinoid nanoparticle carrier composition
View Patent ↗A method of producing a cannabinoid nanoparticle carrier composition for administration to a human, including the steps of incorporating non-ionic surfactants with cannabinoid oils and lipids; inducing sonication for a predetermined period of time at a predetermined amplification with a ultrasonic liquid processor until completely integrated; dissolving ascorbic acid into a carrier fluid; combining in sequence the non-ionic surfactants, lipids, and cannabinoids with a carrier fluid consisting of distilled water and ascorbic acid; sonicating using an ultrasonic liquid processor at predetermined amplitude for a predetermined period of time at a controlled temperature.
1. A method of producing a cannabinoid nanoparticle carrier composition for administration to a human, comprising:
(a) mixing non-ionic surfactants with cannabinoid oils and lipids in a mixing vessel, wherein the non-ionic surfactants, cannabinoid oils, and lipids, respectively, are mixed in relative proportions of 5:9:9 by weight of the total formula weight;
(b) processing the mixture made in step (a) using sonication until completely processed and substantially all of the cannabinoid oils are reduced to nanoparticle size in a cannabinoid oil complex (COC);
(c) dissolving ascorbic acid in a carrier fluid to make an acidic carrier fluid solution, wherein the ascorbic acid is in a relative amount of 0.01-3% by weight of the total formula weight;
(d) mixing the COC made in steps (a) and (b) with the acidic carrier fluid solution made in step (c); and
(e) sonicating the mixture made in step (d) using an ultrasonic liquid processor until substantially all of the cannabinoid oils are reduced to nanoparticle size in a cannabinoid oil composition.
2. The method of claim 1 , wherein said step (a) mixing step comprises mixing approximately 5000 mg of non-ionic surfactants with approximately 9000 mg of cannabinoid oils, and approximately 9000 mg lipids.
3. The method of claim 1 , wherein said step (b) processing step comprises inducing sonication for approximately 90 seconds at 60% amplification.
4. The method of claim 3 , wherein said step (b) processing step involves using an ultrasonic liquid processor.
5. The method of claim 1 , wherein said carrier fluid is selected from the group consisting of distilled water, glycerides, and lipids, and mixtures thereof.
6. The method of claim 5 , wherein the acidic carrier fluid solution comprises approximately 76 g distilled water and 1 g (1000 mg) ascorbic acid.
7. The method of claim 6 , wherein step (e) involves sonicating at 60% using ultrasonic liquid processor.
8. The method of claim 7 , wherein the sonication of step (e) is conducted at 60% amplitude.
9. The method of claim 8 , wherein the sonication of step (e) is continued for approximately 5 minutes.
10. The method of claim 9 , wherein the sonication is carried out at a constant temperature.