IP Library › Granted Patent US 11,832,942
Granted Patent B2
US 11,832,942 · App. 16/962,229 · Granted Dec 5, 2023

Biological material measuring apparatus

Inventors: Kosuke Shinohara (Tokyo, JP); Kentaro Enoki (Tokyo, JP); Koichi Akiyama (Tokyo, JP); Shimpei Ogawa (Tokyo, JP); Daisuke Fujisawa (Tokyo, JP)
Assignee: MITSUBISHI ELECTRIC CORPORATION
A61B5/1455G01N21/359G01N21/41
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Quick Facts
Patent No.
US 11,832,942
App. No.
16/962,229
Granted
Dec 5, 2023
Kind
B2
Abstract

A biological material measuring apparatus includes an infrared light source unit to radiate infrared light in entirety or part of a wavelength region including absorption wavelengths of a biological material, a prism to cause the infrared light radiated from the infrared light source unit to pass therethrough and emit the infrared light to a living body surface while being in contact with the living body surface, a light source to radiate light of a wavelength in a visible light region or a near infrared region to the prism, and a light position detector to detect a path of light from the light source by detecting light from the light source which is emitted from the prism.

Claims (29)

1. A biological. material measuring apparatus comprising:

an infrared light source configured to radiate infrared light in entirety or part of a wavelength region including absorption wavelengths of a biological material;

a prism configured to cause the infrared light radiated from the infrared light source to pass therethrough and emit the infrared light to a living body surface while being in contact with the living body surface;

a light source to radiate light of a wavelength in a visible light region or a near infrared region to the prism; and

a light position detector to detect a path of light from the light source by detecting whether light from the light source which is emitted from the prism includes refracted light.

2. The biological material measuring apparatus according to claim 1 , wherein the infrared light emitted to the living body surface is absorbed by the biological material present in the living body surface, and the absorption generates absorption heat to form a refractive index gradient in the prism.

3. The biological material measuring apparatus according to claim 2 , wherein the light radiated from the light source passes through the refractive index gradient formed in the prism due to the absorption heat of the biological material.

4. The biological material measuring apparatus according to claim 3 , comprising a controller to measure an amount of the biological material based on a difference between a position of incidence of light radiated from the light source which is detected by the light position detector when the infrared light source unit does not radiate the infrared light and a position of incidence of light radiated from the light source which is detected by the light position detector when the infrared light source radiates the infrared light.

5. The biological material measuring apparatus according to claim 1 , wherein the light position detector includes a photodetector, and the light position detector detects the path of the light from the light source by detecting a position at which the light emitted from the prism enters the photodetector.

6. The biological material measuring apparatus according to claim 1 , wherein a change in a state of the prism causes a change in the path of the light from the light source.

7. A biological material measuring apparatus comprising:

an ATR prism adherable to a living body surface;

an infrared light source configured to radiate, to the ATR prism, infrared light in entirety or part of a wavelength region including absorption wavelengths of a biological material; and

an infrared photodetector to detect infrared light of at least one wavelength which is emitted from the ATR prism,

wherein infrared light of one or more wavelengths is a -isorbed upon generation of plasmon resonance in a surface of a light receiving portion of the infrared photodetector, and at least one of the one or more wavelengths corresponds to an absorption wavelength of the biological material.

8. The biological material measuring apparatus according to claim 7 , wherein the infrared light source unit comprises a single light source to radiate infrared light in a wavelength region detectable by the infrared photodetector.

9. The biological material measuring apparatus according to claim 7 , wherein recesses or projections are periodically formed in the surface of the light receiving portion of the infrared photodetector, and an outermost surface of the light receiving portion is a material that causes surface plasmon resonance.

10. The biological material measuring apparatus according to claim 9 , wherein a period of the recesses or the projections in the surface of the light receiving portion of the infrared photodetector corresponds to an absorption wavelength of the biological material.

11. The biological material measuring apparatus according to claim 10 , wherein the infrared light emitted from the ATR prism perpendicularly enters the surface of the light receiving portion of the infrared photodetector.

12. The biological material measuring apparatus according to claim 10 , wherein

the surface of the light receiving portion of the infrared photodetector is formed of a thin metal layer, an intermediate layer, and metal patches stacked in order from inside, and

an absorption wavelength of the biological material is controllable in accordance with a size of each of the metal patches.

13. The biological material measuring apparatus according to claim 12 , wherein a period at which the metal patches are arranged is larger than the absorption wavelength of the biological material and is larger than one side of each of the metal patches.

14. A biological material measuring apparatus comprising:

an ATR prism adherable to a living body surface;

an infrared light source configured to radiate, to the ATR prism, infrared light in entirety or part of a wavelength region including absorption wavelengths of a biological material; and

an infrared photodetector to detect infrared light emitted from the ATR prism,

wherein the infrared light source comprises a plurality of light sources, each of which radiates infrared light of a single wavelength included in a wavelength region detectable by the infrared photodetector, and

infrared light of one or more wavelengths is absorbed upon generation of plasmon resonance in a surface of a light receiving portion of the infrared photodetector, and at least one of the one or more wavelengths corresponds to an absorption wavelength of the biological material.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2020
From: SHINOHARA, KOSUKE; ENOKI, KENTARO; AKIYAMA, KOICHI; OGAWA, SHIMPEI; FUJISAWA, DAISUKE
To: MITSUBISHI ELECTRIC CORPORATION
Reel/Frame 053210/0496 →
Continuity (1)
Related Publication 20210059574A1 · Mar 4, 2021
Cited By (2)
US 12,697,050 US 12,721,550