Method of treating pain
Provided is a method of treating or lessening the severity of pain in a subject, comprising administering to the subject a compound of formula (I), defined as described herein, or a pharmaceutically acceptable salt thereof.
1. A method of treating or lessening the severity of pain in a subject, comprising administering to the subject orally a compound of formula (I)
or a pharmaceutically acceptable salt thereof, wherein:
(a) the compound of formula (I), or a pharmaceutically acceptable salt thereof, is administered every 12 hours in a first dose of 1500 mg and a subsequent dose of 750 mg; or
(b) the compound of formula (I), or a pharmaceutically acceptable salt thereof, is administered every 12 hours in a first dose of 500 mg and a subsequent dose of 250 mg.
2. The method of claim 1 , wherein the compound of formula (I), or a pharmaceutically acceptable salt thereof, is administered every 12 hours in a first dose of 1500 mg and a subsequent dose of 750 mg.
3. The method of claim 2 , wherein the pain is acute pain.
4. The method of claim 3 , wherein the acute pain is acute post-operative pain.
5. The method of claim 2 , wherein the pain is postsurgical pain.
6. The method of claim 5 , wherein the postsurgical pain is bunionectomy pain.
7. The method of claim 1 , wherein the compound of formula (I), or a pharmaceutically acceptable salt thereof, is administered every 12 hours in a first dose of 500 mg and a subsequent dose of 250 mg.
8. The method of claim 7 , wherein the pain is acute pain.
9. The method of claim 8 , wherein the acute pain is acute post-operative pain.
10. The method of claim 7 , wherein the pain is postsurgical pain.
11. The method of claim 10 , wherein the postsurgical pain is bunionectomy pain.