Use of direct-fed microbials in preventing and/or treating
View Patent ↗A composition and method for preventing and/or treating an E. coli -based infection in an animal is described.
1. A method for treating an enterotoxigenic E. coli (ETEC)-based infection in swine which comprises orally administering an effective amount of a composition comprising a Bacillus -based direct-fed microbial component comprising Bacillus strains 3BP5 (NRRL B-50510), 918 (NRRL B-50508), and 15-AP4 (PTA-6507) to the swine.
2. The method of claim 1 wherein the composition produces one or more performance benefits selected from the group consisting of increased bodyweight gain, gain feed ratio, improved gut barrier integrity, reduced mortality, and reduced E. coli shedding in feces.
3. The method of claim 1 wherein the Bacillus -based direct-fed microbial is in the form of an endospore.
4. The method of claim 1 wherein said composition further comprises at least one enzyme which, optionally, may be encapsulated.
5. The method of claim 3 wherein said composition further comprises at least one enzyme which, optionally, may be encapsulated.
6. The method of claim 4 wherein the at least one enzyme is selected from the group consisting of phytase, protease, amylase, xylanase and beta-glucanase.
7. The method of claim 5 wherein the at least one enzyme is selected from the group consisting of phytase, protease, amylase, xylanase and beta-glucanase.
8. The method of claim 1 wherein said composition is a feed additive composition or a premix.
9. The method of claim 3 wherein said composition is a feed additive composition or a premix.
10. The method of claim 4 wherein said composition is a feed additive composition or a premix.