COMBINATION OF LACTOBACILLI FOR THE RELIEF OF IRRITABLE BOWEL SYNDROME AND FOR THE RELIEF OF OTHER GASTROINTESTINAL DISORDERS
Described herein are compositions and methods relating to the use of a combination of live lactobacilli bacteria, particularly live Lactobacillus acidophilus , live Lactobacillus casei , and live Lactobacillus rhamnosus , for the relief of undesirable gastromtestmal health problems such as irritable bowel syndrome (IBS), abdominal pain, abdominal discomfort, bloating, liquid stools and constipation. This combination of live lactobacilli bacteria can also be used for improving quality of life of a subject suffering from IBS, for the relief of IBS, and/or for the prevention and/or treatment of IBS.
1 . (canceled)
2 . A method for improving quality of life of a subject suffering from irritable bowel syndrome (IBS), comprising administering to said subject a combination of live Lactobacillus acidophilus , live Lactobacillus casei , and live Lactobacillus rhamnosus , wherein said administration provides to said subject at least one benefit selected from the group consisting of: satisfaction with bowel habit, minimal interference of IBS with normal activity, improved body image, reduction of food avoidance, increased social reaction, reduced sexual dysfunction, and improved relationships.
3 . The method of claim 2 , wherein said Lactobacillus acidophilus is Lactobacillus acidophilus CL1285® deposited at the CNCM, wherein said Lactobacillus casei is Lactobacillus casei LBC80R® deposited at the CNCM, and wherein said Lactobacillus rhamnosus is Lactobacillus rhamnosus CLR2® deposited at the CNCM.
4 . The method of claim 2 , wherein said administering comprises administration of a nutritionally acceptable composition comprising said combination of Lactobacilli.
5 . The method of claim 2 , wherein said administering comprises administering at least 10 to 200 billion of said combination of Lactobacillus.
6 . The method of claim 2 , wherein said combination of live Lactobacillus acidophilus , live Lactobacillus casei , and live Lactobacillus rhamnosus comprises about 1-10% L. acidophilus, 70-90% L. casei and about 5-20% L. rhamnosus of the colony forming units (CFU) of the combination.
7 . The method of claim 2 , wherein said administering comprises administering said combination of Lactobacilli at least once a day.
8 . The method of claim 2 , wherein said administering comprises administering a capsule comprising said combination of Lactobacilli.
9 . The method of claim 2 , wherein said administering comprises administering a ferment, said ferment comprising fermented proteins in addition to said combination of Lactobacilli.
10 . The method of claim 9 , wherein said fermented proteins are selected from the group consisting of fermented soy proteins, fermented milk proteins, fermented rice proteins, fermented pea proteins, fermented hemp proteins, fermented almond proteins and fermented insect proteins.
11 . A method for the relief of irritable bowel syndrome (IBS) in a human subject in need thereof, comprising administering to said subject a combination of live Lactobacillus acidophilus CL1285®, live Lactobacillus casei LBC80R® and live Lactobacillus rhamnosus CLR2®.
12 . The method of claim 11 , wherein said IBS comprises at least one of constipation-predominant IBS (IBS-C), diarrhea-predominant IBS (IBS-D), and mixed bowel patterns IBS (IBS-M).
13 . The method of claim 11 , wherein said method provides simultaneous relief of multiple symptoms of IBS.
14 . The method of claim 13 , wherein said symptoms are selected from the group consisting of abdominal pain, bloating and constipation.
15 . The method of claim 11 , wherein said administering comprises administration of a nutritionally acceptable composition comprising said combination of Lactobacilli.
16 . The method of claim 11 , wherein said administering comprises administering at least 10 to 200 billion of said combination of Lactobacillus.
17 . The method of claim 11 , wherein said combination of live Lactobacillus acidophilus , live Lactobacillus casei , and live Lactobacillus rhamnosus comprises about 1-10% L. acidophilus, 70-90% L. casei and about 5-20% L. rhamnosus of the colony forming units (CFU) of the combination.
18 . The method of claim 11 , wherein said administering comprises administering said combination of Lactobacilli at least once a day.
19 . The method of claim 11 , wherein said administering comprises administering a capsule comprising said combination of Lactobacilli.
20 . The method of claim 11 , wherein said administering comprises administering a ferment, said ferment comprising fermented proteins in addition to said combination of Lactobacilli.
21 . The method of claim 20 , wherein said fermented proteins are selected from the group consisting of fermented soy proteins, fermented milk proteins, fermented rice proteins, fermented pea proteins, fermented hemp proteins, fermented almond proteins and fermented insect proteins.
22 .- 45 . (canceled)