Method and composition for preserving sodium nitroprusside solutions
A method to extend a shelf life of a sodium nitroprusside solution includes: dissolving about two parts by weight of a 2-hydroxybenzyl alcohol and about one part by weight of a sodium nitroprusside in about seventy-five parts by weight of a polyethylene glycol. Compositions for preserving a sodium nitroprusside solution are also described.
1. A method to extend a shelf life of a sodium nitroprusside solution comprising: dissolving about two parts by weight of a 2-hydroxybenzyl alcohol and about one part by weight of a sodium nitroprusside in about seventy-five parts by weight of a polyethylene glycol.
2. The method of claim 1 , comprising: dissolving 3 g of 2-hydroxybenzyl alcohol and 1.5 g sodium nitroprusside in 100 ml of polyethylene glycol 300 at about 60° C.
3. The method of claim 1 , wherein said polyethylene glycol comprises a polyethylene glycol 300.
4. The method of claim 1 , wherein said polyethylene glycol comprises a PEG-400.
5. The method of claim 1 , wherein said polyethylene glycol comprises a PEG-1000.
6. A composition for preserving a sodium nitroprusside solution comprising: about two parts by weight of a 2-hydroxybenzyl alcohol and about one part by weight of a sodium nitroprusside dissolved in about seventy-five parts by weight of a polyethylene glycol.
7. The composition of claim 6 , comprising: 3 g of 2-hydroxybenzyl alcohol and 1.5 g sodium nitroprusside dissolved in 100 ml of polyethylene glycol 300 at about 60° C.
8. The composition of claim 6 , wherein said sodium nitroprusside solution is capable of catalyzing an indophenol monochloramine reaction.
9. A composition for preserving a sodium nitroprusside solution comprising: about two parts by weight of a 2-hydroxybenzyl alcohol and about one part by weight of a sodium nitroprusside dissolved in a component comprising a liquid selected from the group consisting of polyethylene glycol, ethane-1,2-diol, propane-1,2-diol, a polymer with a H—(O—CH2—CH2)n-OH structure either linear or cross-linked, and a glycopolymer.
10. The composition of claim 9 , wherein the liquid is propane-1,2-diol, and the component comprises up to about 70% water by volume.
11. The composition of claim 9 , wherein the component comprises approximately 30% propane-1,2-diol and approximately 70% water by volume.
12. A composition for preserving a sodium nitroprusside solution comprising: a 2-hydroxybenzyl alcohol and a sodium nitroprusside dissolved in a mixture of propane-1,2-diol and water.
13. The composition of claim 12 , wherein the mixture comprises approximately 30% propane-1,2-diol and approximately 70% water by volume.
14. The composition of claim 13 , wherein the composition comprises approximately 1% sodium nitroprusside by weight.
15. The composition of claim 14 , wherein the ratio of the 2-hydroxybenzyl alcohol to the sodium nitroprusside is about two parts by weight to one part by weight.
16. The composition of claim 12 , wherein the composition comprises approximately 1% sodium nitroprusside by weight.
17. The composition of claim 16 , wherein the ratio of the 2-hydroxybenzyl alcohol to the sodium nitroprusside is about two parts by weight to one part by weight.
18. A method to extend a shelf life of a sodium nitroprusside solution comprising:
dissolving a 2-hydroxybenzyl alcohol and a sodium nitroprusside in a mixture of propane-1,2-diol and water.
19. The method of claim 18 , wherein the mixture comprises approximately 30% propane-1,2-diol and approximately 70% water by volume.
20. The method of claim 19 , wherein the composition comprises approximately 1% sodium nitroprusside by weight.
21. The method of claim 20 , wherein the ratio of the 2-hydroxybenzyl alcohol to the sodium nitroprusside is about two parts by weight to one part by weight.
22. The method of claim 18 , wherein the composition comprises approximately 1% sodium nitroprusside by weight.
23. The method of claim 22 , wherein the ratio of the 2-hydroxybenzyl alcohol to the sodium nitroprusside is about two parts by weight to one part by weight.