IP Library › Granted Patent US 10,987,355
Granted Patent B2
US 10,987,355 · App. 16/983,740 · Granted Apr 27, 2021

Methods and compositions for the treatment of hair loss

Inventor: John Edward Wurst (Poway, CA)
Assignee: Aneira Pharma, Inc.
A61K31/506A61K31/222A61K31/25A61K38/13A61K47/10A61K47/12A61K47/26A61P17/14
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Quick Facts
Patent No.
US 10,987,355
App. No.
16/983,740
Granted
Apr 27, 2021
Kind
B2
Abstract

Compositions and methods for the treatment of hair growth and the prevention of hair loss.

Claims (30)

1. A composition for use in the treatment of hair loss wherein the active agents consist of about 0.05%-0.5% w/v of one selected from the group consisting of latanoprost and latanoprost acid and 1%-8% w/v minoxidil.

2. The composition of claim 1 wherein the composition has about 0.1% w/v latanoprost or latanoprost acid and about 5% w/v minoxidil.

3. The composition of claim 1 wherein the composition has about 0.08% w/v latanoprost or latanoprost acid and about 4% w/v minoxidil.

4. The composition according to claim 1 wherein the composition has about 0.3% w/v latanoprost or latanoprost acid and about 5% w/v minoxidil.

5. The composition of claim 2 further comprising oleyl alcohol or ethanol.

6. The composition of claim 4 further comprising one selected from the group consisting of polyethylene glycol or propylene glycol.

7. The composition of claim 5 further comprising acetic acid and one selected from the group consisting of polysorbate 60 and polyoxyethylene lauryl alcohol.

8. The composition of claim 3 further comprising acetic acid one selected from the group consisting of polysorbate 60 and polyoxyethylene lauryl alcohol.

9. The composition of claim 2 further comprising ethanol and at least one selected form the group consisting of propylene glycol and polysorbate 80.

10. The composition of claim 9 wherein ethanol is present in a concentration of about 25%-30% w/v.

11. The composition of claim 10 wherein the composition further comprises oleyl alcohol.

12. The composition of claim 3 further comprising diethylene glycol monoethyl ether.

13. The composition of claim 4 further comprising ethanol, propylene glycol, water and at least one selected from the group consisting of benzyl alcohol, oleic acid and polyoxyethylene lauryl alcohol.

14. The composition of claim 2 wherein the composition comprises ethanol, propylene glycol, polysorbate, water and at least one selected from the group consisting of acetic acid, oleic acid and benzyl alcohol.

15. The composition of claim 3 wherein the composition comprises propylene glycol, ethanol and acetic acid from about 0.1-0.5% w/v.

16. The composition of claim 3 wherein the composition comprises 50% w/v propylene glycol and 30% w/v ethanol.

17. The composition of claim 2 wherein the composition comprises at least two selected from the group consisting ethanol, propylene glycol, polyoxyethylene 80, and propanediol and at least one selected from the group consisting of acetic acid, oleic acid and oleyl alcohol.

18. The composition according to claim 4 further comprising oleyl alcohol.

19. The composition according to claim 18 further comprising propylene glycol, ethanol, and diethylene glycol monoethyl ether.

20. A composition according to claim 19 wherein the composition comprises 50% w/v propylene glycol, 25% w/v ethanol, 2-5% w/v diethylene glycol monoethyl ether and water.

21. A composition according to claim 2 consisting of 0.1% w/v latanoprost, 5% w/v minoxidil, 2% w/v oleyl alcohol, 50% w/v propylene glycol, 30% w/v ethanol, water and 3% w/v diethylene glycol monoethyl ether.

22. A composition according to claim 3 consisting of 0.08% w/v latanoprost, 4% w/v minoxidil, 3% w/v oleic acid, 50% w/v propylene glycol, 30% w/v ethanol, water and 2% w/v diethylene glycol monoethyl ether.

23. A composition according to claim 2 consisting of about 0. 1% w/v latanoprost, about 5% w/v minoxidil, about 2% w/v oleyl alcohol, about 50% w/v propylene glycol, about 30% w/v ethanol, water and about 3% w/v diethylene glycol monoethyl ether.

24. A composition according to claim 3 consisting of 0.08% w/v latanoprost, 4% w/v minoxidil, 2% w/v oleyl alcohol, 50% w/v propylene glycol, 30% w/v ethanol, water and 3% w/v diethylene glycol monoethyl ether.

25. A composition according to claim 4 consisting of 0.3% w/v latanoprost, 5% w/v minoxidil, 50% w/v ethanol, 30% w/v propylene glycol, 3% w/v diethylene glycol monoethyl ether, 3% w/v oleyl alcohol and water.

26. A composition according to claim 4 consisting of 0.3% w/v latanoprost, 5% w/v minoxidil, 50% w/v ethanol, 30% w/v propylene glycol, 3% w/v diethylene glycol monoethyl ether, 3% w/v oleyl alcohol and water.

27. A composition according to claim 4 consisting of 0.3% w/v latanoprost, 5% w/v minoxidil, 50% w/v propylene glycol, 30% w/v ethanol, 3% w/v diethylene glycol monoethyl ether, 2% w/v oleyl alcohol and water.

28. A composition according to claim 4 consisting of 0.3% w/v latanoprost, 5% w/v minoxidil, 50% w/v propanediol, 30% w/v ethanol, 3% w/v diethylene glycol monoethyl ether, 2% w/v oleyl alcohol, 0.5% w/v polyoxyethylene 40 and water.

29. A composition for use in growing hair on the scalp consisting of latanoprost, minoxidil, oleyl alcohol, ethanol, diethylene glycol monoethyl ether and water.

30. The composition according to claim 29 further comprising acetic acid.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Aug 9, 2020
From: WURST, JOHN EDWARD
To: ANEIRA PHARMA, INC.
Reel/Frame 053439/0167 →
Continuity (4)
Provisional Application 62883809 · Aug 7, 2019
Provisional Application 62895869 · Sep 4, 2019
Provisional Application 63100611 · Mar 23, 2020
Related Publication 20210038600A1 · Feb 11, 2021