IP Library Granted Patent US 11,801,017
Granted Patent B2
US 11,801,017 · App. 16/986,014 · Granted Oct 31, 2023

Focused tomography

Inventors: Timothy Edward Olson (Deland, FL); Stephanie Marie Leon (Newberry, FL)
Assignee: University of Florida Research Foundation, Inc.
A61B6/032A61B6/03A61B6/06A61B6/405A61B6/4028G01N23/046G01N2223/419
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Quick Facts
Patent No.
US 11,801,017
App. No.
16/986,014
Granted
Oct 31, 2023
Kind
B2
Abstract

An exemplary focused tomography system comprises an x-ray transmitter that is configured to emit a radiation beam and an x-ray detector that is configured to detect incident radiation from the radiation beam. The system further includes an adaptive collimator device arranged between the x-ray transmitter and the x-ray detector and a controller device connected to the x-ray transmitter that is configured to cause the x-ray transmitter to emit the radiation beam at a first radiation dosage level when a path of the radiation beam intersects a region of interest of the subject and cause the x-ray transmitter to emit the radiation beam at a second radiation dosage level when the path of the radiation beam does not intersect the region of interest of the subject, such that the second radiation dosage level is less than the first radiation dosage level. Data within the region of interest can be reconstructed with image quality equivalent to traditional computed tomography scans.

Claims (32)

1. A focused tomography system comprising:

an x-ray transmitter that is configured to emit a radiation beam;

an x-ray detector that is configured to detect incident radiation from the radiation beam;

a plurality of collimators arranged between the x-ray transmitter and the x-ray detector, wherein each of the plurality of collimators are formed of a material that passes substantially 10% of incoming radiation, the plurality of collimators comprising at least an adaptive collimator;

wherein the adaptive collimator is configured to transmit the radiation beam at a first radiation dosage level when a path of the radiation beam intersects a region of interest of a subject and transmit the radiation beam at a second radiation dosage level when the path of the radiation beam does not intersect the region of interest of the subject, the second radiation dosage level being less than the first radiation dosage level and greater than 0; and

a controller connected to the focused tomography system that is configured to perform 2-D computerized tomography reconstruction of an image within the region of interest at a first image quality level for the first radiation dosage level and an image outside the region of interest at a second image quality level for the second radiation dosage level, wherein the second image quality level is lower than the first image quality level and an image of an entire slice is displayed at the first image quality level for the region of interest and the second image quality level for a region outside the region of interest.

2. The system of claim 1 , wherein the adaptive collimator provides a pair of sliding collimators that actuate to adjust a size of an opening between the sliding collimators to be adjustable laterally in size, wherein the adaptive collimator is movable, via one or more motors, to position the opening at any lateral position within a scan field-of-view and to configure a size of the opening within a range from fully opened to fully closed during each rotation of the x-ray transmitter around the subject.

3. The system of claim 2 , further comprising a pre-patient filter arranged between the x-ray transmitter and the adaptive collimator, wherein the pre-patient filter comprises a mechanical filter that is controllable by the controller to reduce the radiation dosage level and focus radiation from the x-ray transmitter on the region of interest.

4. The system of claim 1 , wherein the adaptive collimator is formed from aluminum, copper, or tungsten material.

5. The system of claim 1 , wherein the adaptive collimator comprises a pre-patient filter that focuses radiation from the x-ray transmitter on a region of interest.

6. The system of claim 1 , wherein the an x-ray detector is configured to sample the radiation beam at a same rate within the region of interest and outside the region of interest.

7. The system of claim 1 , wherein the adaptive collimator is configured to smoothly transition between the first radiation dosage level and the second radiation dosage level.

8. The system of claim 1 , wherein the second radiation dosage level does not exceed 10% of the first radiation dosage level.

9. The system of claim 1 , wherein the controller is configured to use measurements of the second radiation dosage level outside of the region of interest to determine low frequency components of an image of the region of interest.

10. A focused tomography method comprising:

arranging a plurality of collimators between an x-ray transmitter and an x-ray detector of a gantry for a computerized tomography scanner, wherein each of the plurality of collimators are formed of a material that passes substantially 10% of incoming radiation, the plurality of collimators comprising at least an adaptive collimator;

emitting a radiation beam at a first radiation dosage level when a path of the radiation beam intersects a region of interest and emitting the radiation beam at a second radiation dosage level when the path of the radiation beam does not intersect the region of interest, the second radiation dosage level being less than the first radiation dosage level and greater than 0;

detecting, via the x-ray detector, incident radiation from the radiation beam at the first radiation dosage level;

detecting, via the x-ray detector, incident radiation from the radiation beam at the second radiation dosage level;

performing 2-D computerized reconstruction, via a processor, of an image within the region of interest at a first image quality level for the first radiation dosage level and a region outside the region of interest at a second image quality level for the second radiation dosage level, wherein the second image quality level is lower than the first image quality level; and

displaying an image of an entire slice at both the first image quality level for the region of interest and the second image quality level for a region outside the region of interest.

11. The method of claim 10 , wherein high frequency components of the image are determined solely from the incident radiation at the first radiation dosage level whose path intersects the region of interest, wherein low frequency components of the image are determined from the incident radiation at the first radiation dosage level whose path intersects the region of interest and the incident radiation at the second radiation dosage level that does not intersect the region of interest.

12. The method of claim 10 , wherein the adaptive collimator provides a pair of sliding collimators, the method further comprising:

adjusting, via a controller of the computerized tomography scanner, a size of an opening between the sliding collimators in size in order to restrict a scan field-of-view to a region of interest; and

moving the adaptive collimator to position the opening at any lateral position within the scan field-of-view.

13. The method of claim 12 , further comprising arranging a pre-patient filter between the x-ray transmitter and the adaptive collimator, wherein the pre-patient filter comprises a mechanical filter that is controllable by the controller to reduce the radiation dosage level and focus a radiation beam from the x-ray transmitter on the region of interest.

14. The method of claim 12 , wherein the adaptive collimator comprises a pre-patient filter that focuses radiation from the x-ray transmitter on the region of interest.

15. The method of claim 12 , wherein the size of the opening and/or a positioning of the opening is adjusted during each rotation of the x-ray transmitter around a subject.

16. The method of claim 10 , further comprising selecting the region of interest before emitting a radiation beam.

17. The method of claim 10 , further comprising sampling the radiation beam at a same rate within the region of interest and outside the region of interest.

18. The method of claim 10 , further comprising smoothly transitioning between the first radiation dosage level and the second radiation dosage level.

19. The method of claim 10 , wherein the second radiation dosage level does not exceed 10% of the first radiation dosage level.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2021
From: OLSON, TIMOTHY EDWARD; LEON, STEPHANIE MARIE
To: UNIVERSITY OF FLORIDA RESEARCH FOUNDATION, INCORPORATED
Reel/Frame 054940/0411 →
Continuity (2)
Provisional Application 62884230 · Aug 8, 2019
Related Publication 20210038172A1 · Feb 11, 2021