IP Library Granted Patent US 11,666,593
Granted Patent B2
US 11,666,593 · App. 17/012,591 · Granted Jun 6, 2023

Compositions containing adenosine triphosphate (ATP) and methods of use

Inventors: John Rathmacher (Story City, IA); Lisa Pitchford (Ames, IA); Shawn Baier (Polk City, IA); Larry Kolb (Missoula, MT); Naji Abumrad (Nashville, TN); Matthew Legge (Bannockburn, AU)
A61K31/7076A23L33/125A23L33/15A23L33/175A23L33/18A23L33/30
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Quick Facts
Patent No.
US 11,666,593
App. No.
17/012,591
Granted
Jun 6, 2023
Kind
B2
Abstract

The present invention provides a composition comprising adenosine or adenosine triphosphate (ATP) acting as an absorption enhancer when combined with a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug. Methods of administering ATP or adenosine to improve the bioavailability of a nutritional material(s) such as nutrients, protein, peptides, vitamins, phytochemicals, minerals, fatty acids, or amino acids or a drug are described.

Claims (10)

1. A method for increasing the bioavailability of a nutritional material in an animal comprising administering enterally to the animal at least one nutritional material containing at least one amino acid comprising glutamine, asparagine, alanine, arginine, and/or citrulline; and an effective dosage of an absorption enhancer, wherein the absorption enhancer is adenosine triphosphate (ATP) or adenosine.

2. The method of claim 1 , wherein the nutritional material contains at least one of protein, peptides, and/or individual amino acids.

3. A method for improving the absorption of a nutritional material in a human, comprising administering enterally to the human an effective dosage of an absorption enhancer, wherein the absorption enhancer is adenosine triphosphate (ATP) or adenosine; and at least one nutritional material containing at least one amino acid comprising glutamine, asparagine, alanine, arginine, and/or citrulline.

4. The method of claim 3 , wherein the nutritional material contains at least one of protein, peptides, and/or individual amino acids.

5. The method of claim 4 , wherein the nutritional material contains additional amino acids.

6. The method of claim 5 , wherein the additional amino acids are essential amino acids.

7. The method of claim 5 , wherein the additional amino acids are branched chain amino acids.

8. A method for improving the bioavailability of at least one vitamin in an animal, comprising administering enterally to the animal at least one vitamin and an effective dosage of an absorption enhancer for at least fifteen days, wherein the absorption enhancer is adenosine triphosphate (ATP) or adenosine.

9. The method of claim 8 , wherein the improved bioavailability is measured as a greater increase in blood serum levels of the vitamin as compared to administration of the vitamin without the absorption enhancer.

10. The method of claim 8 , wherein the vitamin is Vitamin K.

Assignments (3)
CHANGE OF NAME Recorded May 12, 2022
From: JIANGYIN TSI PHARMACEUTICAL CO., LTD.
To: TSI GROUP, CO. LTD.
Reel/Frame 059985/0402 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 21, 2020
From: RATHMACHER, JOHN; PITCHFORD, LISA; BAIER, SHAWN; ABUMRAD, NAJI; LEGGE, MATTHEW
To: JIANGYIN TSI PHARMACEUTICAL CO., LTD.
Reel/Frame 054710/0794 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 21, 2020
From: KOLB, LARRY
To: JIANGYIN TSI PHARMACEUTICAL CO., LTD.
Reel/Frame 054711/0268 →
Continuity (3)
Provisional Application 62939986 · Nov 25, 2019
Provisional Application 62896335 · Sep 5, 2019
Related Publication 20210069229A1 · Mar 11, 2021
Cited By (1)
US 12,251,393