IP Library Granted Patent US 11,730,672
Granted Patent B2
US 11,730,672 · App. 17/030,302 · Granted Aug 22, 2023

Implantable electroacupuncture system and method

Inventors: Jeffrey H. Greiner (Valencia, CA); David K. L. Peterson (Valencia, CA); Chuladatta Thenuwara (Castaic, CA); Stacy Greiner Chambliss (Valencia, CA)
Assignee: Valencia Bioscience, Inc.
A61H39/002A61F5/0026A61N1/36085A61N1/36117A61N1/36125A61N1/36175A61N1/3756A61N1/3758A61N1/3782A61N1/37205A61H2201/50A61H2201/5005A61H2201/5038A61H2201/5097A61N1/36153A61N1/36157Y10T29/49117
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Quick Facts
Patent No.
US 11,730,672
App. No.
17/030,302
Granted
Aug 22, 2023
Kind
B2
Abstract

A method comprises generating, by an implantable stimulator, stimulation sessions at a duty cycle that is less than 0.05 and applying, by the implantable stimulator, the stimulation sessions to a patient. The duty cycle is a ratio of T3 to T4. Each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes. The implantable stimulator is powered by a primary battery having an internal impedance greater than 5 ohms.

Claims (37)

1. A method comprising:

generating, by an implantable stimulator, stimulation sessions at a duty cycle that is less than 0.05, wherein

the duty cycle is a ratio of T3 to T4,

each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes, and

the implantable stimulator is powered by a primary battery having an internal impedance greater than 5 ohms; and

applying, by the implantable stimulator, the stimulation sessions to a patient.

2. The method of claim 1 , wherein:

a housing of the implantable stimulator is coin-sized and coin-shaped; and

the primary battery located within the implantable stimulator is a coin-cell battery.

3. The method of claim 1 , wherein the applying of the stimulation sessions to the patient comprises applying the stimulation sessions to a location within the patient that comprises at least one of acupoints ST36, SP4, ST37, ST40, SP6, SP9, K16, and LR8.

4. The method of claim 1 , wherein T3 is at least 10 minutes and less than 60 minutes, and wherein T4 is at least 1440 minutes.

5. The method of claim 1 , wherein the primary battery located within the implantable stimulator has a capacity of less than 60 milliamp-hours (mAh).

6. The method of claim 1 , wherein the applying of the stimulation sessions to the patient is configured to treat at least one of obesity, dyslipidemia, a genitourinary disease, ventricular extrasystoles, an irritable bowel syndrome, asthma, a diabetes neuropathy syndrome, a hyperthyroidism syndrome, facial nerve paralysis, arteriosclerosis, a neurological injury, hypotension, rhinitis, or rheumatoid arthritis of the patient.

7. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the genitourinary disease, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a tibial nerve of the patient.

8. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the ventricular extrasystoles, and wherein the applying of the stimulation session comprises applying the stimulation sessions to one or more of a deep peroneal nerve or a median nerve of the patient.

9. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the irritable bowel syndrome, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises acupoint ST36.

10. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the asthma, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises one or more of acupoints LU1 or BL13.

11. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the hyperthyroidism syndrome, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises one or more of acupoints PE6 or UB15.

12. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the facial nerve paralysis, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises one or more of acupoints ST6, ST7, ST4, L14, L120, SJ17, or GB20.

13. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the arteriosclerosis, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises one or more of acupoints UB18, UB20, or UB23.

14. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the hypotension, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises one or more of acupoint L16, acupoint GB39, a radial nerve, or a peroneal nerve.

15. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the rhinitis, and wherein the applying of the stimulation session comprises applying the stimulation sessions to a location that comprises one or more of acupoint L120 or a nasopalatine nerve.

16. The method of claim 6 , wherein the applying of the stimulation sessions is configured to treat the rheumatoid arthritis, and wherein the applying of the stimulation session comprises applying the stimulation sessions to acupoint GB34.

17. An implantable stimulator, comprising:

a housing;

pulse generation circuitry located within the housing, the pulse generation circuitry configured to

generate stimulation sessions at a duty cycle that is less than 0.05, and

apply the stimulation sessions to a patient by way of an electrode array communicatively coupled to the pulse generation circuitry; and

a primary battery having an internal impedance greater than 5 ohms, the primary battery configured to provide operating power to the pulse generation circuitry;

wherein

the duty cycle is a ratio of T3 to T4, and

each stimulation session included in the stimulation sessions has a duration of T3 minutes and occurs at a rate of once every T4 minutes.

18. The implantable stimulator of claim 17 , wherein:

the housing of the implantable stimulator is coin-sized and coin-shaped; and

the primary battery located within the housing is a coin-cell battery.

19. The implantable stimulator of claim 17 , wherein the applying of the stimulation sessions to the patient is configured to treat at least one of obesity, dyslipidemia, a genitourinary disease, ventricular extrasystoles, an irritable bowel syndrome, asthma, a diabetes neuropathy syndrome, a hyperthyroidism syndrome, facial nerve paralysis, arteriosclerosis, a neurological injury, hypotension, rhinitis, or rheumatoid arthritis of the patient.

20. The implantable stimulator of claim 17 , wherein the primary battery located within the housing has a capacity of less than 60 milliamp-hours (mAh).

Assignments (5)
RELEASE OF SECURITY INTEREST Recorded May 6, 2026
From: MEDTRONIC, INC.
To: VALENCIA BIOSCIENCE, INC.
Reel/Frame 075721/0223 →
SECURITY INTEREST Recorded Oct 27, 2023
From: VALENCIA BIOSCIENCE, INC.
To: MEDTRONIC, INC.
Reel/Frame 065382/0738 →
SECURITY INTEREST Recorded Aug 4, 2021
From: VALENCIA BIOSCIENCE, INC.
To: MEDTRONIC, INC.
Reel/Frame 057088/0352 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 23, 2020
From: GREINER, JEFFREY H.; PETERSON, DAVID K.L.; THENUWARA, CHULADATTA; GREINER, STACY O.
To: VALENCIA TECHNOLOGIES CORPORATION
Reel/Frame 053864/0969 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 23, 2020
From: VALENCIA TECHNOLOGIES CORPORATION
To: VALENCIA BIOSCIENCE, INC.
Reel/Frame 053864/0991 →
Continuity (14)
Continuation 16394932 · Apr 25, 2019
Continuation 15918781 · Mar 12, 2018
Continuation 15421294 · Jan 31, 2017
Continuation 14859098 · Sep 18, 2015
Continuation 13736033 · Jan 7, 2013
Continuation In Part 13622497 · Sep 19, 2012
Provisional Application 61676275 · Jul 26, 2012
Provisional Application 61674691 · Jul 23, 2012
Provisional Application 61673254 · Jul 19, 2012
Provisional Application 61672661 · Jul 17, 2012
Provisional Application 61672257 · Jul 16, 2012
Provisional Application 61609875 · Mar 12, 2012
Provisional Application 61606995 · Mar 6, 2012
Related Publication 20210000687A1 · Jan 7, 2021