IP Library Granted Patent US 11,707,193
Granted Patent B2
US 11,707,193 · App. 17/063,473 · Granted Jul 25, 2023

Systems and methods for using eye movements to determine traumatic brain injury

Inventors: Stephen L. Macknik (Anthem, AZ); Susana Martinez-Conde (Anthem, AZ)
Assignee: DIGNITY HEALTH
A61B3/113A61B5/1103A61B5/4064A61B5/746A61B5/74
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Quick Facts
Patent No.
US 11,707,193
App. No.
17/063,473
Granted
Jul 25, 2023
Kind
B2
Abstract

Systems and methods for detecting a traumatic brain injury (TBI). The system comprises a sensing arrangement and a control unit. The sensing arrangement collects eye movement data of a user. The control unit is in communication with the sensing arrangement and configured to compare the eye movement data to one or more baseline measurements of eye movement dynamics. The control unit is also configured to generate an alert indicating the presence or severity of the TBI for delivery to control unit administrator if the eye movement data diverges from one or more of the baseline measurements by a threshold amount.

Claims (33)

1. A method of determining a traumatic brain injury (TBI) of a user, the method comprising:

a) obtaining eye movement data of one or both of the user's eyes;

b) calculating, from the eye movement data, one or more current intersaccadic drift velocities;

c) comparing the eye movement data, including the one or more current intersaccadic drift velocities, to a data model including intersaccadic drift velocities; and

d) delivering an alert indicating results of the comparison, including one of a presence, absence, progression, or a severity of the TBI.

2. The method of claim 1 , wherein the data model includes a threshold intersaccadic drift velocity.

3. The method of claim 1 , wherein the data model includes a plurality of intersaccadic drift velocities plotted along a curve ranging at least between a threshold-normal value to a threshold-TBI value.

4. The method of claim 1 , wherein the data model includes baseline measurements of eye movement dynamics.

5. The method of claim 4 , wherein the baseline measurements of eye movement dynamics are derived from previous eye movement data of the user.

6. The method of claim 4 , wherein the baseline measurements of eye movement dynamics are derived from eye movement data of a subject other than the user.

7. The method of claim 4 , wherein the baseline measurements of eye movement dynamics are derived from averaged eye movement data of a plurality of subjects other than the user.

8. The method of claim 4 , wherein the baseline measurements of eye movement dynamics are derived from eye movement data of one of the user or a subject other than the user taken in normal conditions without a TBI.

9. The method of claim 4 , wherein the baseline measurements of eye movement dynamics are derived from eye movement data of one of the user or a subject other than the user taken in conditions with a diagnosed TBI.

10. The method of claim 1 , wherein the data model represents a progression of eye movement dynamics of the user from a “normal” condition to an “injury” condition.

11. The method of claim 1 and further comprising calibrating the data model to the user prior to step c).

12. The method of claim 11 , wherein calibrating the data model includes:

obtaining a calibration set of eye movement data of one or both of the user's eyes;

comparing the calibration set of eye movement data to the data model to determine a deviation of the calibration set of eye movement data from the data model; and

adapting the data model to the user based on the comparison.

13. The method of claim 1 , wherein delivering the alert includes providing a visual display of the results.

14. The method of claim 1 , wherein step a) further includes recording the eye movement data from one or both of the user's eyes.

15. The method of claim 14 and further comprising continuing the recording until one of the alert indicates the presence of the TBI, a predetermined time duration has been reached, or a manual request to stop recording has been received.

16. The method of claim 1 and further comprising delivering a secondary alert to take corrective action when the results of the comparison indicate the eye movement data is one of above or within a certain range of a threshold-TBI value.

17. A system for determining or monitoring a traumatic brain injury (TBI) of a user, the system comprising:

a sensing arrangement configured to capture eye movement data of the user;

a control unit in communication with the sensing arrangement, the control unit being configured to:

obtain the eye movement data from the sensing arrangement;

calculate, from the eye movement data, one or more current intersaccadic drift velocities;

compare the eye movement data, including the one or more current intersaccadic drift velocities, to a data model including intersaccadic drift velocities; and

deliver an alert indicating results of the comparison, including one of a presence, absence, progression, or a severity of a TBI.

18. The system of claim 17 , wherein the sensing arrangement is integrated into a handheld scanning device.

19. The system of claim 17 , wherein the sensing arrangement is integrated into eyewear configured to be worn by the user.

20. The system of claim 17 , wherein the control unit includes a data model generator configured to create the data model from prior eye movement data obtained from one of the user or one or more subjects other than the user.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Mar 14, 2023
From: MACKNIK, STEPHEN; MARTINEZ-CONDE, SUSANA
To: DIGNITY HEALTH
Reel/Frame 062977/0022 →
Continuity (4)
Continuation 16264131 · Jan 31, 2019
Continuation 15504166
Provisional Application 62040166 · Aug 21, 2014
Related Publication 20210015361A1 · Jan 21, 2021
Cited By (1)
US 12,201,362