FEED INGREDIENT COMPRISING CLOSTRIDIUM TYROBUTYRICUM
Provided is a feed ingredient comprising at least 20% by weight Clostridium tyrobutyricum , wherein said Clostridium tyrobutyricum comprises at least 70% of dry weight crude protein and optionally at least 7% of dry weight lysine and/or at least 1% of dry weight methionine. Further provided are animal feeds and probiotic compositions comprising the feed ingredient, methods for the production thereof and uses thereof.
1 . A feed ingredient comprising at least 20% by weight Clostridium tyrobutyricum , wherein said Clostridium tyrobutyricum comprises at least 70% of dry weight crude protein and optionally at least 7% of dry weight lysine and/or at least 1% of dry weight methionine.
2 . The feed ingredient of claim 1 , further comprising at least 20% by weights Butyribacterium methylotrophicum.
3 . The feed ingredient of claim 1 , wherein said Clostridium tyrobutyricum is sporulated.
4 . The feed ingredient of claim 1 , wherein said Clostridium tyrobutyricum is in clostridial form.
5 . The feed ingredient of claim 1 , wherein said Clostridium tyrobutyricum is genetically modified.
6 . The feed ingredient of claim 1 , wherein said Clostridium tyrobutyricum is genetically modified by removing or inserting genetic material out of or into the chromosome.
7 . The feed ingredient of claim 1 , wherein said Clostridium tyrobutyricum is adaptively evolved.
8 . An animal feed comprising the feed ingredient according to claim 1 .
9 . The animal feed of claim 8 , further comprising at least one of butyric acid and propionic acid.
10 . A probiotic preparation comprising the feed ingredient according to claim 1 .
11 . The probiotic preparation of claim 10 , being selected from the group consisting of a poultry probiotic preparation, a human probiotic preparation, a swine probiotic preparation, and a companion animal probiotic preparation.
12 . The probiotic preparation of claim 10 , further comprising at least one of Enterococcus faecium, Bacillus subtilis, Bacillus amyloliquefaciens, Lactobacillus acidophilus, Lactobacillus plantarum, Pediococcus acidilactici and Clostridium butyricum.
13 . A method for producing a feed ingredient according to claim 1 , comprising culturing in a fermentation medium Clostridium tyrobutyricum , whereby Clostridium tyrobutyricum cell mass is formed.
14 . The method of claim 13 , wherein said fermentation medium is kept at a pH greater than 5.25.
15 . The method of claim 13 , further comprising mechanical separation of formed cell mass and at least one of washing, drying, pulverizing and pelletizing.
16 . A method for maintaining the good health of an animal comprising feeding said animal an animal feed according to claim 8 .
17 . The method of claim 16 , wherein said animal is selected from the group consisting of finfish and shellfish, larvae, fry, juvenile, and adult fish, poultry, swine, companion animals, other ruminants and humans.
18 . The method of claim 16 , wherein said maintaining good health comprises at least one of reduced susceptibility to enteric pathogens, reduction in bowel inflammation, reduced mortality, improved feed conversion and improved weight gain.
19 . A method for maintaining the good health of an animal comprising feeding said animal a probiotic preparation according to claim 10 .
20 . The method of claim 19 , wherein said maintaining good health comprises at least one of reduced susceptibility to enteric pathogens, reduction in bowel inflammation, reduced mortality, improved feed conversion and improved weight gain.