Granted Patent
B2
US 12,548,243 · App. 17/070,643 · Granted Feb 10, 2026
3D-organized nanomaterials through DNA-prescribed and valence-controlled material
Inventors:
Oleg Gang (Setauket, NY); Ye Tian (Nanjing, CN); Jason S. Kahn (New York, NY); Yan Xiong (New York, NY); Brian Minevich (New York, NY); Sanat K. Kumar (New York, NY)
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Abstract
The present subject matter relates to a voxel and methods of organizing an object into a three-dimensional (3D) array using the voxel. The voxel can include a plurality of frames including at least one single stranded (ss) DNA motif with at least one free base, wherein the at least one ssDNA motif hybridizes with a complementary strand fragment of other frames.
Claims (12)
1 . A voxel, comprising
a plurality of frames including at least one single stranded (ss) DNA motif with at least one free base, wherein the at least one ssDNA motif hybridizes with a complementary strand fragment of other frames through vertex-to-vertex hybridization; and
at least one object, wherein the at least one object is located within the voxel.
2 . The voxel of claim 1 , wherein the plurality of frames comprises stand-alone DNA frames, polyhedral frames, or a combination thereof.
3 . The voxel of claim 1 , wherein the plurality of frames forms a tetrahedra framework, an octahedra framework, a cubic framework, or a combination thereof.
4 . The voxel of claim 1 , wherein the at least one object comprises a gold nano particle, a streptavidin, a protein, a quantum dot (QD), an enzyme, or a combination thereof.
5 . The voxel of claim 4 , wherein the object is a functionalized object.
6 . The voxel of claim 1 , wherein the voxel forms a three-dimensional (3D) origami lattice.
7 . The voxel of claim 6 , wherein the 3D origami lattice is a body-centered-cubic (BCC) lattice, a simple cubic (SC) lattice, or a cubic diamond lattice.
8 . The voxel of claim 1 , wherein the voxel is a DNA-prescribed voxel.
9 . The voxel of claim 1 , wherein the voxel is a valence-controlled voxel.
10 . The voxel of claim 1 , wherein the at least one object comprises a metallic particle, a semiconductor particle, a protein superlattice, or combinations thereof.
Assignments (4)
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Oct 16, 2024
From: BROOKHAVEN SCIENCE ASSOCIATES, LLC
To: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
Reel/Frame 068912/0896 →
CONFIRMATORY LICENSE
Recorded Sep 27, 2023
From: COLUMBIA UNIV NEW YORK MORNINGSIDE
To: UNITED STATES DEPARTMENT OF ENERGY
Reel/Frame 065047/0416 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 19, 2021
From: TIAN, YE
To: BROOKHAVEN SCIENCE ASSOCIATES, LLC
Reel/Frame 057232/0121 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Aug 18, 2021
From: THE TRUSTEES OF COLUMBIA UNIVERSITY IN THE CITY OF NEW YORK
To: TIAN, YE
Reel/Frame 057214/0536 →
Continuity (2)
Provisional Application
62914792
· Oct 14, 2019
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