IP Library › Granted Patent US 11,987,833
Granted Patent B2
US 11,987,833 · App. 17/072,696 · Granted May 21, 2024

Method for producing multi-hydroxy derivatives of polyunsaturated fatty acids

Inventors: Jeong Woo Seo (Daejeon, KR); Jong Jae Yi (Daejeon, KR); Sun Yeon Heo (Daejeon, KR); Young Bae Kim (Daejeon, KR); Chul Ho Kim (Daejeon, KR); Baek Rock Oh (Daejeon, KR); Jung Hyun Ju (Daejeon, KR); Hack Sun Choi (Jeju-si, KR)
Assignee: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
C12P7/6427A61P35/00C11C3/00C12N9/0069C12P17/02
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Quick Facts
Patent No.
US 11,987,833
App. No.
17/072,696
Granted
May 21, 2024
Kind
B2
Abstract

The present invention relates to a novel enzyme capable of producing multi-hydroxy derivatives from polyunsaturated fatty acids and a method for producing multi-hydroxy derivatives of polyunsaturated fatty acids using the same.

Claims (6)

1. A compound having a chemical structure of Chemical Formula 2:

2. A method for inhibiting the proliferation of cancer stem cells in a subject in need thereof, comprising:

combining the compound of claim 1 with a pharmaceutically acceptable substituent to obtain a composition; and

administering the composition to the subject.

3. The method of claim 2 , wherein the cancer stem cells are obtained from human breast cancer.

4. A method for producing the compound of claim 1 , comprising reacting the enzyme having the amino acid sequence of SEQ ID NO: 2 with docosahexaenoic acid (DHA).

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Oct 16, 2020
From: SEO, JEONG WOO; YI, JONG JAE; HEO, SUN YEON; KIM, YOUNG BAE; KIM, CHUL HO; OH, BAEK ROCK; JU, JUNG HYUN; CHOI, HACK SUN
To: KOREA RESEARCH INSTITUTE OF BIOSCIENCE AND BIOTECHNOLOGY
Reel/Frame 054080/0484 →
Priority Claims (4)
KR 10-2018-0043972 · Apr 16, 2018 · national
KR 10-2018-0051695 · May 4, 2018 · national
KR 10-2018-0142895 · Nov 19, 2018 · national
KR 10-2018-0142896 · Nov 19, 2018 · national
Continuity (2)
Continuation In Part PCTKR2019004583 · Apr 16, 2019
Related Publication 20210040518A1 · Feb 11, 2021