IP Library › Granted Patent US 11,702,404
Granted Patent B2
US 11,702,404 · App. 17/077,729 · Granted Jul 18, 2023

GLP-1R modulating compounds

Inventors: Stephen E. Ammann (Redwood City, CA); Gediminas J. Brizgys (San Carlos, CA); James S. Cassidy (Foster City, CA); Elbert Chin (San Mateo, CA); Chienhung Chou (Dublin, CA); Jeromy J. Cottell (Redwood City, CA); Michael Graupe (Pacifica, CA); Chao-I Hung (Foster City, CA); Kavoos Kolahdouzan (San Francisco, CA); Scott D. Schroeder (Union City, CA); Nathan D. Shapiro (Belmont, CA); Daniel G. Shore (Redwood City, CA); Suzanne M. Szewczyk (San Mateo, CA); James G. Taylor (Burlingame, CA); Rhiannon Thomas-Tran (San Jose, CA); Nathan E. Wright (Foster City, CA); Zheng-Yu Yang (Palo Alto, CA); Sheila M. Zipfel (San Mateo, CA)
Assignee: Gilead Sciences, Inc.
C07D401/14A61K45/06C07D235/16C07D401/10C07D403/06C07D405/14C07D409/14C07D413/14C07D417/14C07D471/04C07D493/08
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Quick Facts
Patent No.
US 11,702,404
App. No.
17/077,729
Granted
Jul 18, 2023
Kind
B2
Abstract

The present disclosure provides GLP-1R agonists, and compositions, methods, and kits thereof. Such compounds are generally useful for treating a GLP-1R mediated disease or condition in a human.

Claims (3)

1. A compound, or a pharmaceutically acceptable salt thereof, wherein the compound is:

2. The compound of claim 1 , or a pharmaceutically acceptable salt thereof, wherein the compounds is:

3. A pharmaceutical composition comprising a pharmaceutically effective amount of a compound of claim 1 , or a pharmaceutically acceptable salt thereof, and a pharmaceutically acceptable carrier or excipient.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 19, 2020
From: AMMANN, STEPHEN E.; BRIZGYS, GEDIMINAS J.; CASSIDY, JAMES S.; CHIN, ELBERT; CHOU, CHIENHUNG; COTTELL, JEROMY J.; GRAUPE, MICHAEL; HUNG, CHAO-I; KOLAHDOUZAN, KAVOOS; SCHROEDER, SCOTT D.; SHAPIRO, NATHAN D.; SHORE, DANIEL G.; SZEWCZYK, SUZANNE M.; TAYLOR, JAMES G.; THOMAS-TRAN, RHIANNON; WRIGHT, NATHAN E.; YANG, ZHENG-YU; ZIPFEL, SHEILA M.
To: GILEAD SCIENCES, INC.
Reel/Frame 054421/0375 →
Continuity (3)
Provisional Application 63028187 · May 21, 2020
Provisional Application 62926270 · Oct 25, 2019
Related Publication 20210171499A1 · Jun 10, 2021
Cited By (4)
US 12,421,205 US 12,473,271 US 12,497,382 US 12,570,642