Granted Patent
B2
US 11,466,019 · App. 17/088,325 · Granted Oct 11, 2022
Triazolo[4,5-d] pyramidine derivatives and their use as purine receptor antagonists
Inventors:
Samantha Jane Bamford (Winnersh, GB); Roger John Gillespie (Winnersh, GB); Richard Simon Todd (Winnersh, GB)
Assignee:
Vernalis (R&D) Limited
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Abstract
Compounds of formula (I) that are capable of acting as purine receptor antagonists, pharmaceutical compositions including the compounds, and methods of making the compounds, are disclosed. The compounds and compositions can be used in treating or preventing disorders related to purine receptor hyperfunctioning.
Claims (8)
1. A composition comprising:
(a) a compound of formula:
and
(b) a compound of formula:
2. The composition of claim 1 , further comprising a base.
3. The composition of claim 2 , wherein the base is sodium hydride, triethylamine, N,N-diisopropylethylamine, or potassium carbonate.
4. The composition of claim 1 , wherein the compound of formula:
is a compound of formula:
Assignments (2)
CHANGE OF NAME
Recorded Jan 24, 2022
From: VERNALIS DEVELOPMENT LIMITED
To: LIGAND UK DEVELOPMENT LIMITED
Reel/Frame 058738/0271 →
ASSIGNMENT OF ASSIGNOR'S INTEREST
Recorded Jan 24, 2022
From: VERNALIS (R&D) LIMITED
To: VERNALIS DEVELOPMENT LIMITED
Reel/Frame 058822/0570 →
Priority Claims (1)
GB 0906579
· Apr 16, 2009
· national
Continuity (9)
Division
12997721
Provisional Application
61075538
· Jun 25, 2008