IP Library Granted Patent US 11,653,676
Granted Patent B2
US 11,653,676 · App. 17/106,617 · Granted May 23, 2023

Oligosaccharide compositions for use as animal feed and methods of producing thereof

Inventors: John M. Geremia (Watertown, MA); Raffi Mardirosian (Cambridge, MA); Michael J. Gidding (Cambridge, MA); Anastasia V. Murphy (Attleborough, MA)
Assignee: DSM Nutritional Products, LLC
A23K20/163A23K20/142A23K20/147A23K20/195A23K20/22A23K20/24A23K20/26A23K50/30A23K50/75A61K31/702A61K45/06Y02P20/582
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Quick Facts
Patent No.
US 11,653,676
App. No.
17/106,617
Granted
May 23, 2023
Kind
B2
Abstract

Described herein are methods of producing animal feed made up of oligosaccharide compositions, as well as methods of producing such oligosaccharide compositions and animal feed compositions, and methods of using such animal feed compositions to enhance animal growth.

Claims (34)

1. An animal feed pre-mix, comprising:

a carrier material; and

(ii) a gluco-oligosaccharide composition with a weight average molecular weight between 1000 g/mol and 2000 g/mol,

wherein the carrier material has less than 50 ppm by weight of an antibiotic selected from the group consisting of bacitracin, bacitracin methylene disalicylate, bacitracin-zinc, virginiamycin, bambermycin, avilamycin, and efrotomycin, or any combination thereof.

2. The animal feed pre-mix of claim 1 , wherein at least 10 wt % dry gluco-oligosaccharide composition is present in the animal feed pre-mix.

3. The animal feed pre-mix of claim 1 , wherein the carrier material is selected from the group consisting of ground rice hulls, ground oat hulls, feed grade silica gel, feed grade fumed silica, corn gluten feed, corn gluten meal, dried distiller's grains, clay, vermiculite, diatomaceous earth, milled corn, and combinations of distinct carrier materials recited herein.

4. The animal feed pre-mix of claim 1 , wherein at least 50 dry wt % of the gluco-oligosaccharide composition has a degree of polymerization of at least 3.

5. The animal feed pre-mix of claim 1 , wherein the animal feed is poultry feed.

6. The animal feed pre-mix of claim 5 , wherein the poultry feed:

(i) reduces feed conversion ratio (FCR) by between 1 to 10%; or

(ii) increases average daily weight gain by between 1 to 10%; or

(iii) increases average daily feed intake by between 1 to 10%; or

any combination of (i)-(iii),

when fed to poultry as compared to poultry fed a feed composition without the gluco-oligosaccharide composition.

7. The animal feed pre-mix of claim 1 , wherein the animal feed is swine feed.

8. The animal feed pre-mix of claim 7 , wherein the swine feed:

(i) reduces feed conversion ratio (FCR) by between 1 to 15%; or

(ii) increases average daily weight gain by between 1 to 15%; or

(iii) increases average daily feed intake by between 1 to 15%; or

any combination of (i)-(iii),

when fed to swine as compared to swine fed a feed composition without the gluco-oligosaccharide composition.

9. The animal feed pre-mix of claim 1 , wherein the gluco-oligosaccharide composition is a functionalized gluco-oligosaccharide composition comprising a pendant functional group selected from the group consisting of glucosamine, galactosamine, lactic acid, acetic acid, citric acid, pyruvic acid, succinic acid, glutamic acid, aspartic acid, glucuronic acid, itaconic acid, malic acid, maleic acid, adipic acid, sorbitol, xylitol, arabitol, glycerol, erythritol, mannitol, galacitol, fucitol, iditol, inositol, volemitol, lacitol, propanediol, butanediol, pentanediol, sulfate and phosphate.

10. An animal feed composition, comprising (i) a base feed in addition to (ii) the animal feed pre-mix of claim 1 .

11. The animal feed pre-mix of claim 1 , wherein the moisture content of the animal feed pre-mix is less than 20 wt %.

12. The animal feed pre-mix of claim 1 , wherein at least 10 dry wt % of the gluco-oligosaccharide composition has a degree of polymerization of at least 3.

13. The animal feed pre-mix of claim 1 , wherein the animal feed pre-mix is in a dry, flowable powder form.

14. The animal feed pre-mix of claim 1 , wherein the gluco-oligosaccharide composition is a syrup.

15. The animal feed pre-mix of claim 14 , wherein the syrup has a solids content of at least 60 wt % 60%.

16. The animal feed pre-mix of claim 1 , wherein less than 50 ppm of an antibiotic is present in the animal feed pre-mix.

17. The animal feed pre-mix of claim 1 , wherein the carrier material comprises less than 50 ppm of coccidiostat.

18. The animal feed composition of claim 10 , wherein the animal feed composition further comprises vitamins.

19. The animal feed composition of claim 10 , wherein the animal feed composition further comprises essential amino acids.

20. The animal feed composition of claim 10 , wherein the base feed is fodder, corn-soy based diet, wheat-soy based diet, grass, grain, legumes, hay, stover, straw, silage, wheat, barley, maize, sorghum, rye, oats, triticale, rice, soybeans, peas, seaweed, yeast, molasses, lactose, milk, milk solids, chicken meal, fish meal, bone meal, blood, or a combination of distinct base feeds recited herein.

21. The animal feed composition of claim 10 , wherein less than 50 ppm of coccidiostat is present in the animal feed composition.

Assignments (5)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE SECOND ASSIGNOR NAME PREVIOUSLY RECORDED AT REEL: 061404 FRAME: 0320. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Oct 18, 2022
From: KALEIDO BIOSCIENCES, INC.; CADENA BIO, INC.
To: HERCULES CAPITAL, INC.
Reel/Frame 061700/0414 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 10, 2022
From: HERCULES CAPITAL, INC.
To: DSM NUTRITIONAL PRODUCTS, LLC
Reel/Frame 061362/0001 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Sep 9, 2022
From: KALEIDO BIOSCIENCES, INC.; CARDENA BIO, INC.
To: HERCULES CAPITAL, INC.
Reel/Frame 061404/0320 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2021
From: MIDORI USA, INC.
To: CADENA BIO, INC.
Reel/Frame 056864/0846 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jul 15, 2021
From: GEREMIA, JOHN M.; MARDIROSIAN, RAFFI; GIDDING, MICHAEL J.; MURPHY, ANASTASIA V.
To: MIDORI USA, INC.
Reel/Frame 056886/0992 →
Continuity (7)
Continuation 14995129 · Jan 13, 2016
Provisional Application 62255343 · Nov 13, 2015
Provisional Application 62255341 · Nov 13, 2015
Provisional Application 62216952 · Sep 10, 2015
Provisional Application 62216945 · Sep 10, 2015
Provisional Application 62108037 · Jan 26, 2015
Related Publication 20210076705A1 · Mar 18, 2021
Cited By (3)
US 12,410,206 US 12,508,274 US 12,661,366