Tissue mapping and treatment
Methods, systems, and devices are described for mapping and treating tissue during a medical procedure. In some cases, a device includes a mesh of wires with sensors coupled thereto. The mapping device can be coupled to an expandable treatment element. Alternatively, the treatment device can be a separate device, and advanced through an access lumen in the mapping device. The expandable treatment element can include multiple segments. The sensors can be used to map a tissue area and monitor the tissue during a medical procedure.
1 . A system for determining a control parameter of a treatment device configured to treat atrial fibrillation, the system comprising one or more hardware processors configured to:
determine a threshold energy (“E1”) needed to stimulate a non-targeted tissue proximate a target tissue site;
receive one or more electrical signals responsive to stimulation of the non-targeted tissue;
determine a change in the one or more received electrical signals corresponding to a physical change in the target tissue site, said physical change responsive to treatment of tissue at the target tissue site; and
determine a control parameter based on the threshold energy and a first time (“T1”) corresponding to the determination of the change in the one or more received electrical signals,
wherein the control parameter comprises a treatment time (“Tt”) corresponding to an amount of time for operation of the treatment device, and
wherein the treatment time is a function of a ratio of the determined threshold energy over a predetermined constant threshold (“E2”) corresponding to a safe distance from the non-targeted tissue.
2 . The system of claim 1 , wherein the treatment time is a function of a predetermined treatment time (“Ts”) at the safe distance from the non-targeted tissue.
3 . The system of claim 2 , wherein Tt=T1+ [(E1/E2)×Ts].
4 . The system of claim 3 , wherein the predetermined threshold energy is about 20 mA.
5 . The system of claim 3 , wherein the predetermined treatment time is about 180 seconds.
6 . The system of claim 1 , wherein the threshold energy corresponds to a rheobase curve for the non-targeted tissue.
7 . The system of claim 1 , wherein the one or more hardware processors are further configured to automatically predict treatment success based on the received one or more electrical signals.
8 . The system of claim 7 , the treatment success is determined based on the first time corresponding to the determination of the change in the one or more received electrical signals.
9 . The system of claim 7 , wherein the treatment success is further determined based on a spatial pattern of the change in the one or more received electrical signals.
10 . A method of adjusting therapy delivered by a treatment device configured to treat atrial fibrillation, the method comprising:
determining a threshold energy (“E1”) needed to stimulate a non-targeted tissue proximate a target tissue site;
receiving one or more electrical signals responsive to stimulation of the non-targeted tissue;
determining a change in the one or more received electrical signals corresponding to a physical change in the target tissue site, said physical change responsive to treatment of tissue at the target tissue site;
determining a control parameter based on the threshold energy and a first time (“T1”) corresponding to the determination of the change in the one or more received electrical signals; and
adjusting the treatment device to modify a parameter of therapy in response to the control parameter,
wherein the control parameter comprises a treatment time (“Tt”) corresponding to an amount of time for operation of the treatment device, and
wherein the treatment time is a function of a ratio of the determined threshold energy over a predetermined constant threshold (“E2”) corresponding to a safe distance from the non-targeted tissue.
11 . The method of claim 10 , wherein the treatment time is a function of a predetermined treatment time (“Ts”) at the safe distance from the non-targeted tissue.
12 . The method of claim 11 , wherein Tt=T1+ [(E1/E2)×Ts].
13 . The method of claim 12 , wherein the predetermined threshold energy is about 20 mA.
14 . The method of claim 12 , wherein the predetermined treatment time is about 180 seconds.
15 . The method of claim 10 , wherein the threshold energy corresponds to a rheobase curve for the non-targeted tissue.
16 . The method of claim 10 , further comprising automatically predicting treatment success based on the received one or more electrical signals.
17 . The method of claim 16 , the treatment success is determined based on the first time corresponding to the determination of the change in the one or more received electrical signals.
18 . The method of claim 16 , wherein the treatment success is further determined based on a spatial pattern of the change in the one or more received electrical signals.