IP Library Granted Patent US 11,886,156
Granted Patent B2
US 11,886,156 · App. 17/130,711 · Granted Jan 30, 2024

System and method for user intuitive visual management of automation of bioprocess

Inventors: Dalesh Dharamshi (Uppsala, SE); Sudheer Mygapula (Uppsala, SE)
Assignee: Cytiva Sweden AB
G05B17/02G05B13/041G05B2219/23258G05B2219/23452G05B2219/32341G05B2219/37453Y02P90/02
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Quick Facts
Patent No.
US 11,886,156
App. No.
17/130,711
Granted
Jan 30, 2024
Kind
B2
Abstract

A system for providing an improved way of user intuitive visual management of bioprocess automation is disclosed. The system includes a processor and a memory. The processor is configured to present a graphical presentation of the bioprocess automation script and results associated with execution of the bioprocess automation script of a bioprocess, wherein the graphical presentation comprises an anticipated result and an anticipated flow path associated with the bioprocess; and modify the graphical presentation by varying at least one of the anticipated result and the anticipated flow path.

Claims (36)

1. A system for visual management of bioprocess automation, the system comprising:

a processor and a memory, the processor configured to:

generate a first graphical presentation for the design of a bioprocess automation script configured to execute a bioprocess and results associated with execution of the bioprocess automation script of the bioprocess, wherein the first graphical presentation comprises an anticipated result and an anticipated flow path associated with the bioprocess; and

modify the first graphical presentation by varying at least one of the anticipated result and the anticipated flow path; and

a display for presenting the first graphical presentation and a second graphical presentation of a real-time execution of the bioprocess, wherein the processor is configured to generate the second graphical presentation using data that indicates positions of various parts in a bioprocess equipment that performs the bioprocess.

2. The system of claim 1 , wherein the bioprocess comprises a plurality of phases.

3. The system of claim 2 , wherein the first graphical presentation comprises a plurality of graphical elements, wherein each graphical element is associated with a measurement parameter associated with the bioprocess.

4. The system of claim 3 , wherein the processor modifies the first graphical presentation by editing the graphical element for changing the measurement parameter based on user input thereby varying at least one of the anticipated results and the anticipated flow path of the bioprocess.

5. The system of claim 4 , wherein the graphical element is associated with a phase of the plurality of phases.

6. The system of claim 5 , wherein the graphical element is edited based on user input.

7. The system of claim 3 , wherein the processor:

presents at least one of the anticipated flow path and the anticipated result of the bioprocess; and

modifies at least of the anticipated flow path and the anticipated result based on user input.

8. The system of claim 1 , wherein the display displays a third graphical presentation of an expected execution of the bioprocess along with the second graphical presentation of the real-time execution of the bioprocess.

9. The system of claim 1 , further configured to enable post analysis to be performed after the execution of the bioprocess.

10. The system of claim 1 , wherein the bioprocess includes a chromatography process.

11. The system of claim 1 , wherein the bioprocess automation script includes at least one preset process that may optionally have preset measurement parameters.

12. A method for visual management of bioprocess automation, the method comprising:

presenting a first graphical presentation for the design of a bioprocess automation script configured to execute a bioprocess and results associated with execution of the bioprocess automation script of the bioprocess, wherein the first graphical presentation comprises an anticipated result and an anticipated flow path associated with the bioprocess; and

modifying the first graphical presentation by varying at least one of the anticipated result and the anticipated flow path;

generating a second graphical presentation of a real-time execution of the bioprocess using data that indicates positions of various parts in a bioprocess equipment that performs the bioprocess; and

presenting the second graphical presentation of the real-time execution of the bioprocess,

wherein the second graphical presentation is generated using data that indicates positions of various parts in a bioprocess equipment that performs the bioprocess.

13. The method of claim 12 , wherein the bioprocess comprises a plurality of phases.

14. The method of claim 12 , wherein the first graphical presentation is associated with an anticipated flow path of the bioprocess.

15. The method of claim 14 , wherein the first graphical presentation comprises a plurality of graphical elements, wherein each graphical element is associated with a measurement parameter associated with the bioprocess.

16. The method of claim 15 , wherein modifying the first graphical presentation comprises editing the graphical element for changing the measurement parameter thereby varying at least one of the anticipated result and the anticipated flow path of the bioprocess.

17. The method of claim 16 , wherein the graphical element is associated with a phase of the plurality of phases.

18. The method of claim 17 , wherein the graphical element is edited based on user input.

19. The method of claim 14 further comprising:

presenting at least one of the anticipated flow path and the anticipated result of the bioprocess; and

modifying at least one of the anticipated flow path and the anticipated result based on user input.

20. The method of claim 12 , further comprising displaying a third graphical presentation of an anticipated execution of the bioprocess along with the second graphical presentation of the real-time execution of the bioprocess.

21. The method of claim 12 , further comprising performing post analysis after the execution of the bioprocess.

22. The method of claim 12 , wherein the bioprocess includes a chromatography process.

23. The method of claim 12 , wherein the bioprocess automation script includes at least one preset process that may optionally have preset measurement parameters.

Assignments (2)
CHANGE OF NAME Recorded Dec 28, 2020
From: GE HEALTHCARE BIO-SCIENCES AB
To: CYTIVA SWEDEN AB
Reel/Frame 054855/0895 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 22, 2020
From: MYGAPULA, SUDHEER; DHARAMSHI, DALESH
To: GE HEALTHCARE BIO-SCIENCES AB
Reel/Frame 054727/0548 →
Priority Claims (1)
IN 2185/CHE/2015 · Apr 29, 2015 · national
Continuity (2)
Continuation 15568361
Related Publication 20210109490A1 · Apr 15, 2021