Oral compositions comprising cinnamaldehyde and uses thereof
Oral compositions comprising cinnamaldehyde, and methods or improving circulation and improving circulation by administering such compositions, are described. Methods and uses are describe that include the administration of an effective amount of the oral compositions to improve circulation and increasing nerve sensitization, while also resulting in improved balance, and reduced pain, numbness, and/or tingling in the hands and feet, as well as reduced restlessness, fatigue, and tiredness of the legs.
1. A method of increasing nerve sensation comprising administering a therapeutically effective amount of an oral formulation comprising cinnamaldehyde, cinnamon bark extract, garlic bulb extract, benfotiamine, astragalus root extract, and Panax ginseng root to a subject in need thereof, wherein:
the oral formulation increases nerve sensation in the subject and causes an effect in the subject selected from: not increasing pain, not increasing numbness, not increasing tingling, not increasing fatigue, not decreasing mobility, improving balance, and combinations thereof.
2. The method of claim 1 , wherein the oral formulation further comprises at least one pharmaceutically acceptable excipient.
3. The method of claim 2 , wherein the excipient is selected from the group consisting of rice flour, magnesium stearate, maltodextrin, microcrystalline cellulose, and combinations thereof.
4. The method of claim 1 , wherein the oral formulation is a capsule.
5. The method of claim 4 , wherein the capsule comprises about 125 mg to 175 mg cinnamon bark extract.
6. The method of claim 5 , wherein the capsule comprises about 150 mg cinnamon bark extract.
7. The method of claim 4 , wherein the capsule comprises about 125 mg to 175 mg garlic bulb extract.
8. The method of claim 7 , wherein the capsule comprises about 150 mg garlic bulb extract.
9. The method of claim 4 , wherein the capsule comprises about 75 mg to 125 mg benfotiamine.
10. The method of claim 9 , wherein the capsule comprises about 100 mg benfotiamine.
11. The method of claim 4 , wherein the capsule comprises about 7.5 mg to 12.5 mg of a combination of astragalus root extract and Panax ginseng root.
12. The method of claim 11 , wherein the capsule comprises about 10.0 mg of the combination.
13. The method of claim 1 , wherein the oral formulation is administered one, two, three, or four times a day.
14. The method of claim 13 , wherein the oral formulation is administered as two capsules.
15. The method of claim 1 , wherein the oral formulation is administered for at least one month.
16. The method of claim 1 , wherein the oral formulation is administered for at least two months.
17. The method of claim 1 , wherein the subject has a condition selected from the group consisting of poor circulation, diabetes, reduced nerve sensation, neuropathy, numbness in the extremities, tingling in the extremities, cold hands and feet, poor mobility, poor balance, swelling in lower extremities, fatigue, stinging in arms and legs, and combinations thereof.
18. The method of claim 1 , wherein the subject is identified by analyzing the results of a questionnaire.
19. The method of claim 1 , wherein the oral formulation further comprises black pepper extract.