IP Library Granted Patent US 12,070,622
Granted Patent B2
US 12,070,622 · App. 17/137,222 · Granted Aug 27, 2024

System and method for radiotherapy field delivery time optimization

Inventors: Arturs Meijers (Palo Alto, CA); Perttu Niemela (Espoo, FI); Roni Hytonen (Palo Alto, CA); Reynald Van der Straeten (Brussels, BE); Jan Timmer (Los Altos, CA); Timo Koponen (Espoo, FI); Christel Smith (Santa Barbara, CA); Isabel Huth (Kuerten, DE)
Assignees: VARIAN MEDICAL SYSTEMS THERAPY GMBH & CO KG; VARIAN MEDICAL SYSTEMS INTERNATIONAL AG; VARIAN MEDICAL SYSTEMS
A61N5/1031A61N5/1043
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Quick Facts
Patent No.
US 12,070,622
App. No.
17/137,222
Granted
Aug 27, 2024
Kind
B2
Abstract

Treatment fields can be produced as part of a treatment plan that achieves a desired balance between field delivery time and dose based on machine parameters and knowledge, such as machine-specific beam production, transport and scanning logic, and/or a maximum treatment time value. The treatment parameters can be adjusted using a graphical user interface so that treatment time or dosimetry is prioritized. As a result, the overall treatment time is reduced, and hence treatment quality and patient experience are improved.

Claims (63)

1. A computer-implemented method for radiotherapy treatment planning, the computer-implemented method comprising:

accessing a radiotherapy treatment plan including a plurality of treatment layers, each treatment layer of the plurality of treatment layers including a plurality of spots;

receiving a weight for a treatment time objective of the radiotherapy treatment plan;

modifying a spot from a treatment layer of the plurality of treatment layers based on the weight and a cost of the spot, to produce a modified treatment layer; and

generating a modified radiotherapy treatment plan using the modified treatment layer, wherein the modified radiotherapy treatment plan is operable to be executed by a delivery machine to apply radiotherapy treatment to a target in accordance with the modified radiotherapy treatment plan.

2. The computer-implemented method as described in claim 1 , further comprising:

modifying a plurality of spots of the plurality of treatment layers to produce a plurality of modified treatment layers, wherein said generating the modified radiotherapy treatment plan is performed using the plurality of modified treatment layers.

3. The computer-implemented method as described in claim 1 , wherein said modifying a spot comprises:

removing the spot;

modifying the spot to reduce the cost of the spot; or

redistributing a dose contribution of the spot to one or more neighboring spots.

4. The computer-implemented method as described in claim 1 , further comprising:

receiving a weight for a dosimetric objective of the radiotherapy treatment plan.

5. The computer-implemented method as described in claim 4 , wherein the dosimetric objective comprises:

a dose-volume histogram (DVH) objective;

an equivalent uniform dose (EUD) objective;

a minimum dose objective;

a maximum dose objective; or

a dose fall-off objective.

6. The computer-implemented method as described in claim 4 , further comprising:

dynamically rendering a dose-volume histogram on a graphical user interface of a treatment planning system based on the weight for the treatment time objective of the modified radiotherapy treatment plan and the weight for the dosimetric objective of the radiotherapy treatment plan.

7. The computer-implemented method as described in claim 4 , wherein the weight for the treatment time objective and the weight for the dosimetric objective are defined according to a position of a respective slider rendered on a graphical user interface of a treatment planning system.

8. The computer-implemented method as described in claim 1 , further comprising:

simulating a radiotherapy treatment according to the modified radiotherapy treatment plan to determine if an actual dose, when applied according to the modified radiotherapy treatment plan, will conform with a threshold quality standard for treatment.

9. The computer-implemented method as described in claim 1 , wherein said modifying a spot comprises:

calculating a cost for each spot of the plurality of spots based on a dose associated with the spot and a delivery duration of the spot; and

modifying at least one spot of the plurality of spots having a highest cost.

10. An electronic system for radiotherapy treatment planning, the electronic system comprising:

a display device;

a memory coupled to the display device; and

a processor in communication with the memory, wherein the processor is configured to execute instructions to cause the electronic system to

access a radiotherapy treatment plan including a plurality of treatment layers, each treatment layer of the plurality of treatment layers including a plurality of spots,

assign a weight for a treatment time objective of the radiotherapy treatment plan using input received from a graphical user interface rendered on the display device,

modify a spot from a treatment layer of the plurality of treatment layers based on the weight and a cost of the spot, to produce a modified treatment layer, and

generate a modified radiotherapy treatment plan using the modified treatment layer, wherein the modified radiotherapy treatment plan is operable to be executed by a delivery machine to apply radiotherapy treatment to a target in accordance with the modified radiotherapy treatment plan.

11. The electronic system as described in claim 10 , further comprising:

modifying a plurality of spots of the plurality of treatment layers to produce a plurality of modified treatment layers, wherein said generating the modified radiotherapy treatment plan is performed using the plurality of modified treatment layers.

12. The electronic system as described in claim 10 , wherein modification of the spot includes:

removing the spot;

modifying the spot to reduce the cost of the spot; or

redistributing a dose contribution of the spot to one or more neighboring spots.

13. The electronic system as described in claim 10 , wherein the processor is configured to execute instructions to cause the electronic system to assign a weight for a dosimetric objective of the radiotherapy treatment plan.

14. The electronic system as described in claim 13 , wherein the dosimetric objective includes:

a dose-volume histogram (DVH) objective;

an equivalent uniform dose (EUD) objective;

a minimum dose objective;

a maximum dose objective; or

a dose fall-off objective.

15. The electronic system as described in claim 13 , wherein the processor is configured to execute instructions to cause the electronic system to

dynamically render a dose-volume histogram on the graphical user interface based on the weight for the treatment time objective of the modified radiotherapy treatment plan and the weight for the dosimetric objective of the modified radiotherapy treatment plan.

16. The electronic system as described in claim 13 , wherein the weight for the treatment time objective and the weight for the dosimetric objective are defined according to a position of a respective slider rendered on the graphical user interface.

17. The electronic system as described in claim 10 , wherein the processor is configured to execute instructions to cause the electronic system to

simulate a radiotherapy treatment according to the modified radiotherapy treatment plan to determine if an actual dose, when applied according to the modified radiotherapy treatment plan, will conform with a threshold quality standard.

18. The electronic system as described in claim 10 , wherein modification of the spot comprises:

calculating a cost for each spot of the plurality of spots based on a dose associated with the spot and a delivery duration of the spot; and

modifying at least one spot of the plurality of spots having a highest cost.

19. A non-transitory computer-readable storage medium embodying instructions that, when executed by a processor, cause the processor to perform a method of radiotherapy treatment planning, the method comprising:

accessing a radiotherapy treatment plan including a plurality of treatment layers, each treatment layer of the plurality of treatment layers including a plurality of spots;

assigning a weight for a treatment time objective of the radiotherapy treatment plan based on received inputs;

modifying a spot from a treatment layer of the plurality of treatment layers based on the weight and a cost of the spot to produce a modified treatment layer; and

generating a modified radiotherapy treatment plan using the modified treatment layer, wherein the modified radiotherapy treatment plan is operable to be executed by a delivery machine to apply radiotherapy treatment to a target in accordance with the modified radiotherapy treatment plan.

20. The non-transitory computer-readable storage medium as described in claim 19 , wherein the method further comprises:

modifying a plurality of spots from the plurality of treatment layers to produce a plurality of modified treatment layers, wherein said generating a modified radiotherapy treatment plan is performed using the plurality of modified treatment layers.

Assignments (7)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 12, 2025
From: VARIAN MEDICAL SYSTEMS, INC.
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 073197/0490 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Dec 12, 2025
From: VARIAN MEDICAL SYSTEMS PARTICLE THERAPY GMBH & CO. KG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 073197/0407 →
CHANGE OF NAME Recorded Sep 11, 2024
From: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
To: SIEMENS HEALTHINEERS INTERNATIONAL AG
Reel/Frame 068946/0110 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 10, 2021
From: HYTONEN, RONI
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 058856/0187 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 10, 2021
From: SMITH, CHRISTEL; TIMMER, JAN
To: VARIAN MEDICAL SYSTEMS, INC.
Reel/Frame 058073/0468 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 10, 2021
From: NIEMELA, PERTTU; KOPONEN, TIMO
To: VARIAN MEDICAL SYSTEMS INTERNATIONAL AG
Reel/Frame 058073/0046 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Nov 10, 2021
From: MEIJERS, ARTURS; HUTH, ISABEL; VAN DER STRAETEN, REYNALD
To: VARIAN MEDICAL SYSTEMS THERAPY GMBH & CO. KG
Reel/Frame 058096/0268 →
Continuity (2)
Continuation In Part 17115639 · Dec 8, 2020
Related Publication 20220176156A1 · Jun 9, 2022