Granted Patent
B2
US 12,269,864 · App. 17/140,449 · Granted Apr 8, 2025
Self-assembling collagen-like polypeptides for applications and uses related thereto
Inventors:
Vincent Conticello (Avondale Estates, GA); Andrea Merg (Atlanta, GA); Gavin Touponse (Fort Worth, TX)
Assignee:
Emory University
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Abstract
This disclosure relates to collagen-like polypeptides and materials containing the same and uses in biomedical applications. In certain embodiments, this disclosure contemplates that collagen-like polypeptides and materials containing the same are functionalized with proteins or small molecules to create useful scaffolds for drug delivery or testing. In certain embodiments, collagen-like polypeptides and materials containing the same are used in cardiac patches, cosmetic surgery, bone grafts, tissue regeneration, and wound healing.
Claims (2)
1. A composition comprising a first polypeptide and a second polypeptide, wherein the first polypeptide comprises the amino acid sequence of (Pro-Arg-Gly) 4 -(Pro-Hyp-Gly) 6 (SEQ ID NO: 1); and wherein the second polypeptide comprises the amino acid sequence of (Pro-Hyp-Gly) 6 -(Glu-Hyp-Gly) 4 (SEQ ID NO: 2).
2. A composition comprising a first polypeptide and a second polypeptide, wherein the first polypeptide comprises the amino acid sequence of (Pro-Arg-Gly) 6 -(Pro-Hyp-Gly) 6 (SEQ ID NO: 3); and wherein the second polypeptide comprises the amino acid sequence of (Pro-Hyp-Gly) 6 -(Glu-Hyp-Gly) 4 (SEQ ID NO: 2).
Assignments (1)
CONFIRMATORY LICENSE
Recorded Jun 10, 2021
From: EMORY UNIVERSITY
To: NATIONAL SCIENCE FOUNDATION
Reel/Frame 056495/0498 →
Continuity (2)
Provisional Application
62957061
· Jan 3, 2020
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