CREATINE ORAL SUPPLEMENTATION USING CREATINE HYDROCHLORIDE SALT
The present invention is directed to an oral supplement including creatine hydrochloride, which has an aqueous solubility that is at least 15 times greater than creatine monohydrate, where the oral supplement drives significant improvements in muscle development and recovery due to its enhanced bio-availability, while causing fewer negative side effects compared to previous forms of creatine.
1 . A nutritional supplement comprising:
a granular precipitate comprising creatine hydrochloride, wherein the granular precipitate has an aqueous solubility of at least about 150 mg/mL in water at 25° C. after a time period of about 1.5 hours.
2 . The nutritional supplement of claim 1 , wherein the granular precipitate comprises at least 95 percent creatine hydrochloride by weight of the granular precipitate.
3 . The nutritional supplement of claim 1 , wherein the granular precipitate has an aqueous solubility of at least 600 mg/mL in water at 25° C. after a time period of about 1.5 hours.
4 . The nutritional supplement of claim 1 , comprised in a powder.
5 . The nutritional supplement of claim 1 , comprised in an additive or feed supplement for livestock.
6 . The nutritional supplement of claim 1 , comprised in an oral dosage form.
7 . A nutritional supplement comprising:
a granular precipitate comprising creatine hydrochloride, wherein the granular precipitate has an aqueous solubility in water of at least an order of magnitude greater than creatine monohydrate.
8 . The nutritional supplement of claim 7 , further comprising at least one additive comprising one or more proteins, amino acid supplements, carbohydrates, D-Ribose, fats, fiber, sweeteners, flavoring agents, or combinations thereof.
9 . The nutritional supplement of claim 7 , wherein the granular precipitate comprises at least about 95 percent creatine hydrochloride by weight of the granular precipitate.
10 . The nutritional supplement of claim 7 , comprised in an oral dosage form.
11 . The nutritional supplement of claim 10 , wherein the oral dosage form is a powder.
12 . The nutritional supplement of claim 10 , wherein the oral dosage form is a pill, capsule, tablet, or liquid.
13 . The nutritional supplement of claim 8 , wherein the at least one additive is a sweetener selected from the group consisting of sucralose, aspartame, saccharin, acesulfame potassium, neohesperidin dihydrochalcone, glycyrrhizin, thaumatin, alitame, stevioside, and combinations thereof.
14 . The nutritional supplement of claim 13 , further comprising a flavoring agent selected from the group consisting of cocoa, yogurt, peanut butter, mint, cheesecake, hazelnut paste, almonds, granola, coconut, strawberry, banana, cherry, plum, raspberry, lemon, orange, lime, pineapple, blueberry and other fruit flavors, coffee, cremes, jellies, and combinations thereof.
15 . A nutritional supplement comprising:
a granular precipitate comprising creatine hydrochloride, wherein the granular precipitate has an aqueous solubility of at least about 150 mg/mL in water at 25° C. after a time period of about 1.5 hours; and
at least one additive comprising one or more proteins, amino acid supplements, carbohydrates, D-Ribose, fats, fiber, sweeteners, flavoring agents, or combinations thereof.
16 . The nutritional supplement of claim 15 , wherein the granular precipitate comprises at least 95 percent creatine hydrochloride by weight of the granular precipitate.
17 . The nutritional supplement of claim 15 , comprised in a pill, tablet, capsule, or liquid.
18 . The nutritional supplement of claim 15 , comprised in a powder.
19 . The nutritional supplement of claim 15 , wherein the granular precipitate has an aqueous solubility of at least 600 mg/mL in water at 25° C. after a time period of about 1.5 hours.