IP Library Granted Patent US 11,617,733
Granted Patent B2
US 11,617,733 · App. 17/149,327 · Granted Apr 4, 2023

Bicyclic compound and use thereof for medical purposes

Inventors: Tohru Kambe (Osaka, JP); Toru Maruyama (Osaka, JP); Shinsaku Yamane (Osaka, JP); Satoshi Nakayama (Osaka, JP); Kousuke Tani (Osaka, JP)
Assignee: ONO PHARMACEUTICAL CO., LTD.
A61K31/335A61K9/0048A61K31/4427A61K31/558C07D313/06C07D401/06C07D405/06C07D407/12C07D417/04
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Quick Facts
Patent No.
US 11,617,733
App. No.
17/149,327
Granted
Apr 4, 2023
Kind
B2
Abstract

Since a compound represented by the general formula (I) (wherein definition of each group is as described in the specification), a salt thereof, a solvate thereof, or a prodrug thereof has strong and sustaining intraocular pressure lowering activity and, further, has no side effect on eyes such as ocular stimulating property (hyperemia, corneal clouding etc.), aqueous humor protein rise etc., it has high safety, and can be an excellent agent for preventing and/or treating glaucoma etc.

Claims (2)

1. A method of treating a human with glaucoma, comprising administering an effective amount of the compound of formula (I),

wherein the administering lowers intraocular pressure of the human.

Priority Claims (1)
JP 2009-175246 · Jul 28, 2009 · national
Continuity (8)
Continuation 16698432 · Nov 27, 2019
Continuation 16229446 · Dec 21, 2018
Continuation 15852493 · Dec 22, 2017
Continuation 15180125 · Jun 13, 2016
Continuation 14587829 · Dec 31, 2014
Continuation 14081286 · Nov 15, 2013
Continuation 13384383
Related Publication 20210169842A1 · Jun 10, 2021
Cited By (1)
US 12,201,603