IP Library Granted Patent US 12,274,413
Granted Patent B2
US 12,274,413 · App. 17/154,486 · Granted Apr 15, 2025

Autonomous robotic catheter for minimally invasive interventions

Inventors: Pierre E. Dupont (Boston, MA); Georgios Fagogenis (Athens, GR); Benoit Rosa (Sarrebourg, FR); Margherita Mencattelli (Brooklyn, NY); Zurab Machaidze (Lexington, MA)
Assignee: Children's Medical Center Corporation
A61B1/00006A61B1/000094A61B1/000096A61B1/00097A61M25/0116A61M2205/332A61M2205/3327A61M2205/583
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Quick Facts
Patent No.
US 12,274,413
App. No.
17/154,486
Granted
Apr 15, 2025
Kind
B2
Abstract

A robotic system comprising a robotic catheter steerable by a motorized drive system, an imaging device positioned on a distal end of the robotic catheter, and a controller configured to: process one or more images captured by the imaging device to identify an anatomical feature, implanted device, or medical instrument; estimate a location of the imaging device in the body based on the identified anatomical feature, implanted device, or medical instrument; determine, based on the estimated location of the imaging device, a direction in which to steer the robotic catheter for advancement towards an interventional site; and monitor at least one of (i) a stream of images captured by the imaging device and (ii) a force or distance measurement captured by the imaging device or a sensor proximate the imaging device, to adjust the direction in which to steer the robotic catheter during advancement towards the interventional site.

Claims (62)

1. A robotic system, comprising:

a robotic catheter steerable by a motorized drive system;

an imaging device positioned on a distal end of the robotic catheter; and

a controller configured to:

process one or more images captured by the imaging device to identify an anatomical feature, implanted device, or medical instrument in the one or more images,

estimate a location of the imaging device in a body based on the identified anatomical feature, implanted device, or medical instrument,

determine, based on the estimated location of the imaging device, a direction in which to steer the robotic catheter for advancement towards an interventional site, and

monitor at least one of (i) a stream of images captured by the imaging device and (ii) force or distance measurements captured by the imaging device or by a sensor proximate the imaging device, to adjust the direction in which to steer the robotic catheter during advancement towards the interventional site,

wherein monitoring a stream of images captured by the imaging device to adjust the direction in which to steer the robotic catheter includes identifying whether the imaging device is contacting the anatomical feature, implanted device, or medical instrument based on whether at least a portion of an image of the stream of images is unobstructed by bodily fluid.

2. The robotic system of claim 1 , wherein the robotic catheter is comprised of two or more concentric tubes.

3. The robotic system of claim 1 , wherein the motorized drive system is operable to rotate and translate the robotic catheter.

4. The robotic system of claim 1 , wherein the imaging device includes one of an image sensor, a camera, an ultrasonic probe, or other device configured to capture the one or more images.

5. The robotic system of claim 1 , wherein the controller is configured to adjust the direction in which to steer the robotic catheter so as to maintain constant or intermittent contact with an anatomical feature during advancement towards the interventional site.

6. The robotic system of claim 1 ,

wherein the imaging device includes an imaging window covering the imaging device.

7. The robotic system of claim 6 ,

wherein the imaging window includes a surface configured to displace bodily fluid from a contact interface between the imaging window and the anatomical feature, implanted device, or medical instrument.

8. The robotic system of claim 1 , wherein processing one or more images captured by the imaging device includes comparing the one or more of the captured images to representative images of one or more anatomical features, implanted devices, or medical instruments present along a pathway to a interventional site.

9. The robotic system of claim 1 , wherein estimating a location of the imaging device in the body includes identifying the location of the identified anatomical feature, implanted device, or medical instrument in an anatomical model.

10. The robotic system of claim 9 , wherein the anatomical model is non-dimensional.

11. The robotic system of claim 1 , wherein determining the direction in which to steer the robotic catheter for advancement towards a interventional site includes determining a vector between the estimated location of the imaging device and the interventional site using an anatomical model.

12. The robotic system of claim 1 , wherein monitoring a force measurement to adjust the direction in which to steer the robotic catheter includes determining whether the force measurement is substantially non-zero.

13. The robotic system of claim 1 ,

wherein the controller is further configured to estimate an orientation of the imaging device relative to the anatomical feature based on a distribution of a contacting surface area with respect to a center of the image.

14. The robotic system of claim 1 , wherein monitoring a distance measurement to adjust the direction in which to steer the robotic catheter includes determining a distance to the anatomical feature, implanted device, or medical instrument.

15. The robotic system of claim 14 , wherein the controller is configured to adjust the direction in which to steer the robotic catheter so as to avoid contact with an anatomical feature during advancement towards the interventional site.

16. A robotic system, comprising:

a robotic catheter steerable by a motorized drive system;

an imaging device positioned on a distal end of the robotic catheter; and

a controller configured to:

process one or more images captured by the imaging device to identify an anatomical feature, implanted device, or medical instrument in the one or more images,

estimate a location of the imaging device in a body based on the identified anatomical feature, implanted device, or medical instrument,

determine, based on the estimated location of the imaging device, a direction in which to steer the robotic catheter for advancement towards an interventional site, and

monitor at least one of (i) a stream of images captured by the imaging device and (ii) force or distance measurements captured by the imaging device or by a sensor proximate the imaging device, to adjust the direction in which to steer the robotic catheter during advancement towards the interventional site;

wherein the controller is further configured to estimate a contact force between the imaging device and the anatomical feature based on how much of the one or more images is unobstructed by bodily fluid.

17. The robotic system of claim 16 , wherein the controller is further configured to use the estimated contact force or the force measurement to avoid generating unsafe contact forces between the imaging device and the anatomical feature, the implanted device, or the medical instrument.

18. The robotic system of claim 16 , wherein the robotic catheter is comprised of two or more concentric tubes.

19. The robotic system of claim 16 , wherein the motorized drive system is operable to rotate and translate the robotic catheter.

20. The robotic system of claim 16 , wherein the imaging device includes one of an image sensor, a camera, an ultrasonic probe, or other device configured to capture the one or more images.

21. The robotic system of claim 16 , wherein the controller is configured to adjust the direction in which to steer the robotic catheter so as to maintain constant or intermittent contact with an anatomical feature during advancement towards the interventional site.

22. The robotic system of claim 16 , wherein the imaging device includes an imaging window covering the imaging device.

23. The robotic system of claim 22 , wherein the imaging window includes a surface configured to displace bodily fluid from a contact interface between the imaging window and the anatomical feature, implanted device, or medical instrument.

24. The robotic system of claim 16 , wherein processing one or more images captured by the imaging device includes comparing the one or more of the captured images to representative images of one or more anatomical features, implanted devices, or medical instruments present along a pathway to an interventional site.

25. The robotic system of claim 16 , wherein estimating a location of the imaging device in the body includes identifying the location of the identified anatomical feature, implanted device, or medical instrument in an anatomical model.

26. The robotic system of claim 16 , wherein determining the direction in which to steer the robotic catheter for advancement towards an interventional site includes determining a vector between the estimated location of the imaging device and the interventional site using an anatomical model.

27. The robotic system of claim 26 , wherein the anatomical model is non-dimensional.

28. The robotic system of claim 16 , wherein the controller is further configured to estimate an orientation of the imaging device relative to the anatomical feature based on a distribution of a contacting surface area with respect to a center of the image.

29. The robotic system of claim 16 , wherein monitoring a force measurement to adjust the direction in which to steer the robotic catheter includes determining whether the force measurement is substantially non-zero.

30. A method for controlling a robotic system, the method comprising:

providing a robotic catheter steerable by a motorized drive system, the robotic catheter including an imaging device positioned on a distal end of the robotic catheter;

processing one or more images captured by the imaging device to identify an anatomical feature, implanted device, or medical instrument in the one or more images;

estimating a location of the imaging device in a body based on the identified anatomical feature, implanted device, or medical instrument;

determining, based on the estimated location of the imaging device, a direction in which to steer the robotic catheter for advancement towards an interventional site,

monitoring at least one of (i) a stream of images captured by the imaging device and (ii) force or distance measurements captured by the imaging device or by a sensor proximate the imaging device, to adjust the direction in which to steer the robotic catheter during advancement towards the interventional site; and

estimating a contact force between the imaging device and the anatomical feature based on how much of the one or more images is unobstructed by bodily fluid.

31. A method of controlling a robotic system, the method comprising:

providing a robotic catheter steerable by a motorized drive system, the robotic catheter including an imaging device positioned on a distal end of the robotic catheter;

processing one or more images captured by the imaging device to identify an anatomical feature, implanted device, or medical instrument in the one or more images;

estimating a location of the imaging device in a body based on the identified anatomical feature, implanted device, or medical instrument;

determining, based on the estimated location of the imaging device, a direction in which to steer the robotic catheter for advancement towards an interventional site; and

monitoring at least one of (i) a stream of images captured by the imaging device and (ii) force or distance measurements captured by the imaging device or by a sensor proximate the imaging device, to adjust the direction in which to steer the robotic catheter during advancement towards the interventional site;

wherein monitoring the stream of images captured by the imaging device to adjust the direction in which to steer the robotic catheter includes identifying whether the imaging device is contacting the anatomical feature, implanted device, or medical instrument based on whether at least a portion of an image of the stream of images is unobstructed by bodily fluid.

Assignments (2)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Jan 17, 2025
From: DUPONT, PIERRE E.; FAGOGENIS, GEORGIOS; MENCATTELLI, MARGHERITA; ROSA, BENOIT; MACHAIDZE, ZURAB
To: CHILDREN'S MEDICAL CENTER CORPORATION
Reel/Frame 069920/0518 →
CONFIRMATORY LICENSE Recorded Nov 2, 2023
From: BOSTON CHILDREN'S HOSPITAL
To: NATIONAL INSTITUTES OF HEALTH (NIH), U.S. DEPT. OF HEALTH AND HUMAN SERVICES (DHHS), U.S. GOVERNMENT
Reel/Frame 065431/0071 →
Continuity (2)
Provisional Application 62965554 · Jan 24, 2020
Related Publication 20210236773A1 · Aug 5, 2021
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