IP Library › Granted Patent US 12,051,488
Granted Patent B2
US 12,051,488 · App. 17/163,438 · Granted Jul 30, 2024

Interactive trial design platform

Inventors: Jaydeep Bhattacharyya (Acton, MA); James Bolognese (Woodbridge, NJ); Alexandre Buer (Holliston, MA); Eric Edwards (Nolensville, TN); Stanley Y. Huang (Wellesley, MA); Yannis Jemiai (Lexington, MA); Cyrus Mehta (Cambridge, MA); Nitin Patel (Cambridge, MA); Anne Pelz (Arlington, MA); Ajay Prabhakar Sathe (Pune, IN); Joshua A. Schultz (Boston, MA); Pralay Senchaudhuri (Cambridge, MA)
Assignee: Cytel Inc.
G16H10/20G06F30/27G06N5/04G06N20/00G06Q10/067G06Q10/101G16H40/20G16H50/50G06F3/0484G06F2111/06
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Quick Facts
Patent No.
US 12,051,488
App. No.
17/163,438
Granted
Jul 30, 2024
Kind
B2
Abstract

A method for trial design includes presenting on a graphical interface, a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs. The method further includes: monitoring a first set of user interactions with the set of cards; determining a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions; and presenting on the graphical interface a new card that is representative of a trial design consistent with the determined user preference. The method may also include monitoring a second set of user interactions with the new card and refining the determined user preference based at least in part on the second set of user interactions with the new card.

Claims (45)

1. A method comprising:

presenting on a graphical interface, via at least one processor, a set of cards wherein each card in the set is representative of a different trial design from a set of trial designs;

monitoring, via the at least one processor, a first set of user interactions with the set of cards;

determining, via the at least one processor, a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions;

presenting on the graphical interface, via the at least one processor, a new card that is representative of a trial design consistent with the determined user preference;

monitoring, via the at least one processor, a second set of user interactions with the new card; and

refining, via the at least one processor, the determined user preference based at least in part on the second set of user interactions with the new card.

2. The method of claim 1 further comprising:

emphasizing, via the at least one processor, values shown on each card based on a relative value compared to other displayed cards.

3. The method of claim 1 , wherein the interactions include at least one of moving a card, saving a card, or deleting a card.

4. The method of claim 1 , wherein the new card is added to the set of cards.

5. The method of claim 1 , wherein the new card replaces a card from the set of cards.

6. The method of claim 1 , wherein the set of cards is representative of Pareto designs.

7. The method of claim 1 , wherein each card represents a different trial type.

8. The method of claim 1 , wherein the set of cards is representative of convex hull designs.

9. The method of claim 1 further comprising:

saving, via the at least one processor, at least some of the first and the second sets of user interactions; and

training, via the at least one processor, an artificial intelligence model to identify preferences based on interactions.

10. The method of claim 1 further comprising:

determining the user preference for the one or more values of the one or more parameters of the set of trial designs via an artificial intelligence model trained on historical interactions.

11. The method of claim 1 , further comprising:

evaluating historical trial design selections to identify the one or more parameters of the set of trial designs based at least in part on the first set of user interactions;

obtaining trial design simulation results based at least in part on a quick search data structure and the one or more parameters;

generating a substitute for at least some of the trial design simulation results based at least in part on a relationship between the trial design simulation results and supplemental data;

generating a performance surface based at least in part on a set of trial designs corresponding to the trial design simulation results;

evaluating one or more trial designs based at least in part on the performance surface; and

calculating a score based on normalized score component values corresponding to the trial design simulation results.

12. A system comprising:

an electronic device having an electronic display; and

a server in electronic communication with the electronic device and including at least one processor structured to:

present, on the electronic display, a graphical interface having a set of cards, wherein each card in the set is representative of a different trial design from a set of trial designs;

monitor, a first set of user interactions with the set of cards;

determine, a user preference for one or more values of one or more parameters of the set of trial designs from the first set of user interactions;

present, in the graphical interface, a new card that is representative of a trial design consistent with the determined user preference;

monitor a second set of user interactions with the new card; and

refine the determined user preference based at least in part on the second set of user interactions with the new card.

13. The system of claim 12 , wherein the at least one processor refines that determined user preference by storing at least some of the first or the second set of user interactions and determines at least one additional user preference based at least in part on the stored user interactions.

14. The system of claim 12 , wherein the at least one processor is further structured to:

emphasize values shown on each card based on a relative value compared to other displayed cards.

15. The system of claim 12 , wherein the interactions include at least one of moving a card, saving a card, or deleting a card.

16. The system of claim 12 , wherein the new card is added to the set of cards.

17. The system of claim 12 , wherein the new card replaces a card from the set of cards.

18. The system of claim 12 , wherein the set of cards is representative of Pareto designs.

19. The system of claim 12 , wherein each card represents a different trial type.

20. The system of claim 12 , wherein the set of cards is representative of convex hull designs.

Assignments (1)
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 10, 2021
From: BHATTACHARYYA, JAYDEEP; BOLOGNESE, JAMES; BUER, ALEXANDRE; EDWARDS, ERIC; HUANG, STANLEY Y.; JEMIAI, YANNIS; MEHTA, CYRUS; PATEL, NITIN; PELZ, ANNE; SATHE, AJAY PRABHAKAR; SCHULTZ, JOSHUA A.; SENCHAUDHURI, PRALAY
To: CYTEL INC.
Reel/Frame 056186/0679 →
Continuity (8)
Continuation PCTUS2021015954 · Jan 30, 2021
Provisional Application 63086474 · Oct 1, 2020
Provisional Application 63085700 · Sep 30, 2020
Provisional Application 63037977 · Jun 11, 2020
Provisional Application 63002197 · Mar 30, 2020
Provisional Application 63002253 · Mar 30, 2020
Provisional Application 62968874 · Jan 31, 2020
Related Publication 20210241866A1 · Aug 5, 2021
Cited By (3)
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