IP Library Granted Patent US 11,320,503
Granted Patent B2
US 11,320,503 · App. 17/168,929 · Granted May 3, 2022

MPI imaging device, method for generating a magnetic field with a gradient and a field-free line by means of an MPI imaging device

Inventors: Jochen Franke (Karlsruhe, DE); Volker Niemann (Ispringen, DE)
G01R33/383G01R33/445G01R33/4831
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Quick Facts
Patent No.
US 11,320,503
App. No.
17/168,929
Granted
May 3, 2022
Kind
B2
Abstract

An MPI imaging device for mapping an object to be examined in a sample volume, with a magnet arrangement which is designed to generate an MPI magnetic field with a gradient B1 and a field-free line in the sample volume, the magnet arrangement comprising a first pair of magnet rings with two magnet rings in a Halbach dipole configuration, which are arranged coaxially on a common Z axis that runs through the sample volume, wherein the magnet arrangement comprises a second pair of magnet rings with two further magnet rings in a Halbach dipole configuration, which is arranged coaxially in relation to the first pair of magnet rings, the magnet rings of both pairs being arranged rotatably with respect to one another about the Z axis. As a result, a variable MPI selection field can be generated by means of permanent magnets.

Claims (17)

1. An MPI imaging device for mapping an object to be examined in a sample volume, with a magnet arrangement that generates an MPI magnetic field with a gradient B1 and a field-free line in the sample volume, the magnet arrangement comprising:

a first pair of magnet rings in a Halbach dipole configuration, which are arranged coaxially on a common Z axis that runs through the sample volume; and

a second pair of magnet rings in a Halbach dipole configuration, which is arranged coaxially in relation to the first pair of magnet rings, the magnet rings of both pairs being arranged rotatably with respect to one another about the Z axis.

2. The MPI imaging device as claimed in claim 1 , wherein the magnet rings of each pair of magnet rings can be mechanically coupled, so that the first pair of magnet rings and the second pair of magnet rings are rotatable with respect to one another about the Z axis.

3. The MPI imaging device as claimed in claim 1 , wherein all of the magnet rings of the magnet arrangement can be mechanically coupled, so that the magnet arrangement as a whole is rotatable about the Z axis.

4. The MPI imaging device as claimed in claim 1 , further comprising an MPI excitation coil system for generating at least one excitation magnetic field.

5. The MPI imaging device as claimed in claim 1 , wherein the device comprises a shift-field coil system, which is set up to shift the field-free line along at least one spatial direction quasi-statically or with a shift frequency within the sample volume.

6. The MPI imaging device as claimed in claim 1 , wherein the MPI imaging device is configured to be operated in an MPI mode and in at least one further imaging mode.

7. The MPI imaging device as claimed in claim 6 , wherein said further imaging mode is an MRI mode for recording magnetic resonance imaging images, and wherein the magnet arrangement is configured to generate in the MRI mode a B0 field with a B0 isocenter, suitable for MRI measurements, due to dipole magnetization directions of the magnet rings of one of said pairs of magnet rings being aligned parallel to an XY plane perpendicular to the Z axis.

8. The MPI imaging device as claimed in claim 7 , wherein the first pair of magnet rings and the second pair of magnet rings each have parallel-aligned dipole magnetization directions, and wherein an amplitude of the B0 field may be varied by rotating the two pairs of magnet rings in relation to one another.

9. A method for generating a magnetic field with a gradient B1 and a field-free line in a sample volume by means of an MPI imaging device as claimed in claim 1 , comprising aligning the magnet rings of the first pair of magnet rings with respect to one another such that they have antiparallel dipole magnetization directions.

10. The method as claimed in claim 9 , wherein the magnet rings of the second pair of magnet rings are aligned with respect to one another such that they have parallel dipole magnetization directions.

11. The method as claimed in claim 10 , wherein the pairs of magnet rings are aligned with respect to one another such that the dipole magnetization directions of the magnet rings of the second pair of magnet rings are aligned parallel to the dipole magnetization direction of one of the magnet rings of the first pair of magnet rings.

12. The method as claimed in claim 10 , wherein the pairs of magnet rings are aligned with respect to one another such that the dipole magnetization directions of the magnet rings of the second pair of magnet rings include an angle of 0°<α<180° relative to the dipole magnetization directions of the magnet rings of the first pair of magnet rings.

13. The method as claimed in claim 9 , wherein the magnet rings of the second pair of magnet rings are aligned with respect to one another such that they have antiparallel dipole magnetization directions.

14. The method as claimed in claim 13 , wherein the pairs of magnet rings are aligned with respect to one another such that the dipole magnetization directions of the magnet rings of the second pair of magnet rings are aligned parallel or antiparallel to the dipole magnetization directions of the magnet rings of the first pair of magnet rings.

15. The method as claimed in claim 13 , wherein the pairs of magnet rings are aligned with respect to one another such that the dipole magnetization directions of the magnet rings of the second pair of magnet rings include an angle of 0°<α<180° relative to the dipole magnetization directions of the magnet rings of the first pair of magnet rings.

Assignments (4)
CORRECTIVE ASSIGNMENT TO CORRECT THE THE NATURE OF CONVEYANCE PREVIOUSLY RECORDED AT REEL: 67364 FRAME: 778. ASSIGNOR(S) HEREBY CONFIRMS THE ASSIGNMENT. Recorded Jun 12, 2024
From: BRUKER BIOSPIN MRI GMBH
To: BRUKER BIOSPIN GMBH & CO. KG
Reel/Frame 067884/0303 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded May 9, 2024
From: BRUKER BIOSPIN MRI GMBH
To: BRUKER BIOSPIN GMBH & CO. KG
Reel/Frame 067364/0778 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2021
From: FRANKE, JOCHEN
To: BRUKER BIOSPIN MRI GMBH
Reel/Frame 055166/0588 →
ASSIGNMENT OF ASSIGNOR'S INTEREST Recorded Feb 5, 2021
From: NIEMANN, VOLKER
To: BRUKER BIOSPIN MRI GMBH
Reel/Frame 055166/0693 →
Priority Claims (1)
DE 10 2020 202 097.3 · Feb 19, 2020 · national
Continuity (1)
Related Publication 20210255263A1 · Aug 19, 2021